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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF291
Full Name:
S phase cyclin A-associated protein in the endoplasmic reticulum
Alias:
SCAPE; S-phase cyclin A-associated protein in the ER; Zfp291
Type:
Unknown function
Mass (Da):
158156
Number AA:
1399
UniProt ID:
Q9BY12
International Prot ID:
IPI00307114
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
S
F
Q
R
S
N
S
H
D
K
V
R
Site 2
S9
A
S
F
Q
R
S
N
S
H
D
K
V
R
R
I
Site 3
S31
A
R
N
L
I
A
W
S
V
P
L
E
S
K
D
Site 4
S51
K
C
Q
T
G
G
K
S
K
R
T
I
Q
G
T
Site 5
T58
S
K
R
T
I
Q
G
T
H
K
T
T
K
Q
S
Site 6
T61
T
I
Q
G
T
H
K
T
T
K
Q
S
T
A
V
Site 7
S75
V
D
C
K
I
T
S
S
T
T
G
D
K
H
F
Site 8
S85
G
D
K
H
F
D
K
S
P
T
K
T
R
H
P
Site 9
T87
K
H
F
D
K
S
P
T
K
T
R
H
P
R
K
Site 10
T89
F
D
K
S
P
T
K
T
R
H
P
R
K
I
D
Site 11
Y101
K
I
D
L
R
A
R
Y
W
A
F
L
F
D
N
Site 12
Y117
R
R
A
V
D
E
I
Y
V
T
C
E
S
D
Q
Site 13
T119
A
V
D
E
I
Y
V
T
C
E
S
D
Q
S
V
Site 14
S125
V
T
C
E
S
D
Q
S
V
V
E
C
K
E
V
Site 15
T159
L
Q
E
K
L
E
K
T
D
A
Q
S
R
P
T
Site 16
S163
L
E
K
T
D
A
Q
S
R
P
T
S
L
A
W
Site 17
T166
T
D
A
Q
S
R
P
T
S
L
A
W
E
V
K
Site 18
S167
D
A
Q
S
R
P
T
S
L
A
W
E
V
K
K
Site 19
S176
A
W
E
V
K
K
M
S
P
G
R
H
V
I
P
Site 20
S184
P
G
R
H
V
I
P
S
P
S
T
D
R
I
N
Site 21
T187
H
V
I
P
S
P
S
T
D
R
I
N
V
T
S
Site 22
S194
T
D
R
I
N
V
T
S
N
A
R
R
S
L
N
Site 23
S199
V
T
S
N
A
R
R
S
L
N
F
G
G
S
T
Site 24
S232
V
K
A
H
H
T
G
S
T
A
S
S
E
I
T
Site 25
S236
H
T
G
S
T
A
S
S
E
I
T
P
A
Q
S
Site 26
T239
S
T
A
S
S
E
I
T
P
A
Q
S
C
P
P
Site 27
S243
S
E
I
T
P
A
Q
S
C
P
P
M
T
V
Q
Site 28
T248
A
Q
S
C
P
P
M
T
V
Q
K
A
S
R
K
Site 29
T266
K
D
A
E
G
W
E
T
V
Q
R
G
R
P
I
Site 30
S277
G
R
P
I
R
S
R
S
T
A
V
M
P
K
V
Site 31
T278
R
P
I
R
S
R
S
T
A
V
M
P
K
V
S
Site 32
S293
L
A
T
E
A
T
R
S
K
D
D
S
D
K
E
Site 33
S297
A
T
R
S
K
D
D
S
D
K
E
N
V
C
L
Site 34
T320
G
Q
F
V
G
D
G
T
S
N
T
I
E
S
H
Site 35
S321
Q
F
V
G
D
G
T
S
N
T
I
E
S
H
P
Site 36
S326
G
T
S
N
T
I
E
S
H
P
K
D
S
L
H
Site 37
S331
I
E
S
H
P
K
D
S
L
H
S
C
D
H
P
Site 38
T343
D
H
P
L
A
E
K
T
Q
F
T
V
S
T
L
Site 39
T346
L
A
E
K
T
Q
F
T
V
S
T
L
D
D
V
Site 40
S356
T
L
D
D
V
K
N
S
G
S
I
R
D
N
Y
Site 41
S358
D
D
V
K
N
S
G
S
I
R
D
N
Y
V
R
Site 42
Y363
S
G
S
I
R
D
N
Y
V
R
T
S
E
I
S
Site 43
S367
R
D
N
Y
V
R
T
S
E
I
S
A
V
H
I
Site 44
S370
Y
V
R
T
S
E
I
S
A
V
H
I
D
T
E
Site 45
T387
S
V
M
L
Q
A
G
T
P
P
L
Q
V
N
E
Site 46
S411
I
E
N
E
M
D
P
S
D
I
S
N
S
M
A
Site 47
S414
E
M
D
P
S
D
I
S
N
S
M
A
E
V
L
Site 48
S416
D
P
S
D
I
S
N
S
M
A
E
V
L
A
K
Site 49
S441
A
N
E
E
A
I
A
S
A
I
A
E
E
E
Q
Site 50
T450
I
A
E
E
E
Q
L
T
R
E
I
E
A
E
E
Site 51
T465
N
N
D
I
N
I
E
T
D
N
D
S
D
F
S
Site 52
S469
N
I
E
T
D
N
D
S
D
F
S
A
S
M
G
Site 53
S472
T
D
N
D
S
D
F
S
A
S
M
G
S
G
S
Site 54
S474
N
D
S
D
F
S
A
S
M
G
S
G
S
V
S
Site 55
Y496
W
N
D
V
L
A
D
Y
E
A
R
E
S
W
R
Site 56
T506
R
E
S
W
R
Q
N
T
S
W
G
D
I
V
E
Site 57
S531
I
H
M
H
E
K
L
S
S
P
S
R
K
R
T
Site 58
S532
H
M
H
E
K
L
S
S
P
S
R
K
R
T
I
Site 59
T538
S
S
P
S
R
K
R
T
I
A
E
S
K
K
K
Site 60
S542
R
K
R
T
I
A
E
S
K
K
K
H
E
E
K
Site 61
T565
E
K
L
R
E
E
K
T
L
K
L
Q
K
L
L
Site 62
S642
N
K
R
H
D
V
L
S
K
L
K
E
Y
E
Q
Site 63
T731
E
E
R
L
A
A
L
T
A
A
Q
Q
E
A
M
Site 64
S772
E
K
A
A
E
L
S
S
G
R
H
A
N
T
D
Site 65
T778
S
S
G
R
H
A
N
T
D
Y
A
P
K
L
T
Site 66
Y780
G
R
H
A
N
T
D
Y
A
P
K
L
T
P
Y
Site 67
T785
T
D
Y
A
P
K
L
T
P
Y
E
R
K
K
Q
Site 68
Y787
Y
A
P
K
L
T
P
Y
E
R
K
K
Q
C
S
Site 69
S794
Y
E
R
K
K
Q
C
S
L
C
N
V
L
I
S
Site 70
S808
S
S
E
V
Y
L
F
S
H
V
K
G
R
K
H
Site 71
T823
Q
Q
A
V
R
E
N
T
S
I
Q
G
R
E
L
Site 72
S831
S
I
Q
G
R
E
L
S
D
E
E
V
E
H
L
Site 73
S887
F
R
A
K
E
Y
E
S
L
M
E
T
K
N
S
Site 74
T891
E
Y
E
S
L
M
E
T
K
N
S
G
S
D
S
Site 75
S894
S
L
M
E
T
K
N
S
G
S
D
S
P
Y
K
Site 76
S896
M
E
T
K
N
S
G
S
D
S
P
Y
K
A
K
Site 77
S898
T
K
N
S
G
S
D
S
P
Y
K
A
K
L
Q
Site 78
Y900
N
S
G
S
D
S
P
Y
K
A
K
L
Q
R
L
Site 79
S920
K
Q
V
Q
V
Q
D
S
G
S
W
A
N
N
K
Site 80
S922
V
Q
V
Q
D
S
G
S
W
A
N
N
K
V
S
Site 81
S985
V
L
R
I
P
P
K
S
L
C
N
A
I
N
V
Site 82
Y993
L
C
N
A
I
N
V
Y
N
L
T
C
N
N
C
Site 83
T996
A
I
N
V
Y
N
L
T
C
N
N
C
S
E
N
Site 84
T1014
V
L
F
S
N
K
I
T
F
L
M
D
L
L
I
Site 85
T1025
D
L
L
I
H
Q
L
T
V
Y
V
P
D
E
N
Site 86
Y1027
L
I
H
Q
L
T
V
Y
V
P
D
E
N
N
T
Site 87
T1040
N
T
I
L
G
R
N
T
N
K
Q
V
F
E
G
Site 88
T1076
D
G
N
C
Q
P
A
T
P
K
I
P
T
Q
E
Site 89
S1089
Q
E
M
K
N
K
P
S
Q
G
D
P
F
N
N
Site 90
Y1157
F
A
V
T
G
R
S
Y
S
I
F
D
N
N
R
Site 91
S1158
A
V
T
G
R
S
Y
S
I
F
D
N
N
R
Q
Site 92
S1199
H
G
T
I
L
D
P
S
T
A
S
P
K
E
N
Site 93
T1200
G
T
I
L
D
P
S
T
A
S
P
K
E
N
Y
Site 94
S1202
I
L
D
P
S
T
A
S
P
K
E
N
Y
T
Q
Site 95
Y1207
T
A
S
P
K
E
N
Y
T
Q
N
T
I
Q
V
Site 96
S1252
A
F
R
H
M
A
S
S
L
L
G
H
C
S
Q
Site 97
S1261
L
G
H
C
S
Q
V
S
C
E
S
L
L
H
E
Site 98
S1289
D
N
Q
V
I
V
Q
S
G
R
H
P
T
V
L
Site 99
T1294
V
Q
S
G
R
H
P
T
V
L
Q
K
L
C
Q
Site 100
Y1325
P
S
L
I
A
A
C
Y
N
N
H
Q
N
K
I
Site 101
T1353
F
I
Q
D
L
A
Q
T
P
G
Q
A
E
N
Q
Site 102
Y1362
G
Q
A
E
N
Q
P
Y
Q
P
K
G
K
C
L
Site 103
S1371
P
K
G
K
C
L
G
S
Q
D
Y
L
E
L
A
Site 104
Y1374
K
C
L
G
S
Q
D
Y
L
E
L
A
N
R
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation