KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TEX15
Full Name:
Testis-expressed sequence 15 protein
Alias:
Cancer/testis antigen 42
Type:
Mass (Da):
315362
Number AA:
2789
UniProt ID:
Q9BXT5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
P
S
D
A
K
D
S
V
N
Site 2
S8
M
P
S
D
A
K
D
S
V
N
G
D
L
L
L
Site 3
T18
G
D
L
L
L
N
W
T
S
L
K
N
I
L
S
Site 4
S19
D
L
L
L
N
W
T
S
L
K
N
I
L
S
G
Site 5
T37
S
F
P
L
H
N
N
T
G
S
S
T
V
T
T
Site 6
S39
P
L
H
N
N
T
G
S
S
T
V
T
T
S
K
Site 7
T41
H
N
N
T
G
S
S
T
V
T
T
S
K
S
I
Site 8
T43
N
T
G
S
S
T
V
T
T
S
K
S
I
K
D
Site 9
T44
T
G
S
S
T
V
T
T
S
K
S
I
K
D
P
Site 10
S45
G
S
S
T
V
T
T
S
K
S
I
K
D
P
R
Site 11
S47
S
T
V
T
T
S
K
S
I
K
D
P
R
L
M
Site 12
S59
R
L
M
R
R
E
E
S
M
G
E
Q
S
S
T
Site 13
S65
E
S
M
G
E
Q
S
S
T
A
G
L
N
E
V
Site 14
T66
S
M
G
E
Q
S
S
T
A
G
L
N
E
V
L
Site 15
S78
E
V
L
Q
F
E
K
S
S
D
N
V
N
S
E
Site 16
S79
V
L
Q
F
E
K
S
S
D
N
V
N
S
E
I
Site 17
S84
K
S
S
D
N
V
N
S
E
I
K
S
T
P
S
Site 18
S88
N
V
N
S
E
I
K
S
T
P
S
N
S
A
S
Site 19
T89
V
N
S
E
I
K
S
T
P
S
N
S
A
S
S
Site 20
S91
S
E
I
K
S
T
P
S
N
S
A
S
S
S
E
Site 21
S93
I
K
S
T
P
S
N
S
A
S
S
S
E
V
V
Site 22
S95
S
T
P
S
N
S
A
S
S
S
E
V
V
P
G
Site 23
S97
P
S
N
S
A
S
S
S
E
V
V
P
G
D
R
Site 24
T108
P
G
D
R
A
V
L
T
N
G
L
D
T
P
C
Site 25
T118
L
D
T
P
C
F
K
T
S
V
N
D
S
Q
S
Site 26
S125
T
S
V
N
D
S
Q
S
W
A
H
N
M
G
S
Site 27
Y135
H
N
M
G
S
E
D
Y
D
C
I
P
P
N
K
Site 28
S156
C
K
D
Q
G
N
F
S
F
P
I
S
V
S
N
Site 29
S166
I
S
V
S
N
V
V
S
E
V
E
N
Q
N
H
Site 30
S185
A
Q
R
A
Q
Q
E
S
G
N
A
Y
T
K
E
Site 31
Y189
Q
Q
E
S
G
N
A
Y
T
K
E
Y
S
S
H
Site 32
T190
Q
E
S
G
N
A
Y
T
K
E
Y
S
S
H
I
Site 33
S194
N
A
Y
T
K
E
Y
S
S
H
I
F
Q
D
S
Site 34
S201
S
S
H
I
F
Q
D
S
Q
S
S
D
L
K
T
Site 35
S203
H
I
F
Q
D
S
Q
S
S
D
L
K
T
I
Y
Site 36
T208
S
Q
S
S
D
L
K
T
I
Y
Q
T
G
C
Q
Site 37
Y210
S
S
D
L
K
T
I
Y
Q
T
G
C
Q
T
S
Site 38
S217
Y
Q
T
G
C
Q
T
S
T
V
F
P
L
K
K
Site 39
T218
Q
T
G
C
Q
T
S
T
V
F
P
L
K
K
K
Site 40
S227
F
P
L
K
K
K
V
S
I
D
E
Y
L
Q
N
Site 41
Y231
K
K
V
S
I
D
E
Y
L
Q
N
T
G
K
M
Site 42
S247
N
F
A
D
L
E
D
S
S
K
H
E
E
K
Q
Site 43
S248
F
A
D
L
E
D
S
S
K
H
E
E
K
Q
T
Site 44
T255
S
K
H
E
E
K
Q
T
S
W
K
E
I
D
N
Site 45
S256
K
H
E
E
K
Q
T
S
W
K
E
I
D
N
D
Site 46
T265
K
E
I
D
N
D
F
T
N
E
T
K
I
S
P
Site 47
S271
F
T
N
E
T
K
I
S
P
I
D
N
Y
I
V
Site 48
Y276
K
I
S
P
I
D
N
Y
I
V
L
H
Q
E
Y
Site 49
Y283
Y
I
V
L
H
Q
E
Y
K
E
S
E
S
H
N
Site 50
S286
L
H
Q
E
Y
K
E
S
E
S
H
N
S
F
G
Site 51
S288
Q
E
Y
K
E
S
E
S
H
N
S
F
G
K
S
Site 52
S291
K
E
S
E
S
H
N
S
F
G
K
S
C
D
K
Site 53
S295
S
H
N
S
F
G
K
S
C
D
K
I
L
I
T
Site 54
T302
S
C
D
K
I
L
I
T
Q
E
L
E
I
T
K
Site 55
T308
I
T
Q
E
L
E
I
T
K
S
S
T
S
T
I
Site 56
S310
Q
E
L
E
I
T
K
S
S
T
S
T
I
K
D
Site 57
S333
L
E
W
Q
I
T
P
S
F
E
S
L
S
Q
K
Site 58
S336
Q
I
T
P
S
F
E
S
L
S
Q
K
H
P
Q
Site 59
S338
T
P
S
F
E
S
L
S
Q
K
H
P
Q
H
S
Site 60
S345
S
Q
K
H
P
Q
H
S
V
E
Y
E
G
N
I
Site 61
S355
Y
E
G
N
I
H
T
S
L
A
I
A
Q
K
L
Site 62
Y374
L
G
K
I
N
Q
N
Y
A
S
I
I
T
E
A
Site 63
Y403
I
D
T
V
I
S
S
Y
N
I
E
T
A
H
D
Site 64
T407
I
S
S
Y
N
I
E
T
A
H
D
S
S
N
C
Site 65
S411
N
I
E
T
A
H
D
S
S
N
C
S
I
T
R
Site 66
S412
I
E
T
A
H
D
S
S
N
C
S
I
T
R
E
Site 67
S433
K
N
E
N
E
P
V
S
L
E
N
I
Q
R
D
Site 68
Y441
L
E
N
I
Q
R
D
Y
K
E
T
A
Y
V
E
Site 69
T444
I
Q
R
D
Y
K
E
T
A
Y
V
E
D
R
G
Site 70
Y446
R
D
Y
K
E
T
A
Y
V
E
D
R
G
Q
D
Site 71
S490
E
A
K
E
N
S
A
S
C
V
E
N
N
I
E
Site 72
S507
Y
G
D
K
K
Q
D
S
H
T
N
E
N
F
S
Site 73
T509
D
K
K
Q
D
S
H
T
N
E
N
F
S
N
I
Site 74
Y524
D
E
K
E
D
K
N
Y
H
N
I
E
I
L
S
Site 75
S531
Y
H
N
I
E
I
L
S
S
E
E
F
S
T
K
Site 76
S532
H
N
I
E
I
L
S
S
E
E
F
S
T
K
F
Site 77
T562
L
L
E
S
E
E
D
T
I
S
A
V
K
Q
K
Site 78
S564
E
S
E
E
D
T
I
S
A
V
K
Q
K
D
T
Site 79
T571
S
A
V
K
Q
K
D
T
E
N
T
G
R
S
V
Site 80
S583
R
S
V
E
H
L
A
S
T
T
F
P
K
T
A
Site 81
T584
S
V
E
H
L
A
S
T
T
F
P
K
T
A
S
Site 82
T585
V
E
H
L
A
S
T
T
F
P
K
T
A
S
S
Site 83
S592
T
F
P
K
T
A
S
S
S
V
C
V
A
S
N
Site 84
S613
S
A
T
M
P
A
L
S
L
N
N
D
D
H
Q
Site 85
Y622
N
N
D
D
H
Q
I
Y
Q
F
K
E
T
C
S
Site 86
T627
Q
I
Y
Q
F
K
E
T
C
S
S
E
S
P
D
Site 87
S630
Q
F
K
E
T
C
S
S
E
S
P
D
F
G
L
Site 88
S632
K
E
T
C
S
S
E
S
P
D
F
G
L
L
V
Site 89
S644
L
L
V
K
H
R
V
S
D
C
E
I
D
T
D
Site 90
T650
V
S
D
C
E
I
D
T
D
K
N
K
S
Q
E
Site 91
S655
I
D
T
D
K
N
K
S
Q
E
S
F
H
Q
S
Site 92
S658
D
K
N
K
S
Q
E
S
F
H
Q
S
I
N
E
Site 93
S662
S
Q
E
S
F
H
Q
S
I
N
E
N
L
V
L
Site 94
S671
N
E
N
L
V
L
Q
S
I
E
L
E
S
E
I
Site 95
S709
L
C
E
E
F
V
T
S
Y
K
A
L
K
S
R
Site 96
S715
T
S
Y
K
A
L
K
S
R
I
S
W
E
G
L
Site 97
S735
G
E
M
E
V
L
E
S
T
T
G
R
E
N
S
Site 98
S742
S
T
T
G
R
E
N
S
D
Q
H
Y
S
K
E
Site 99
Y746
R
E
N
S
D
Q
H
Y
S
K
E
S
N
Y
F
Site 100
Y752
H
Y
S
K
E
S
N
Y
F
Y
S
S
T
Q
N
Site 101
Y754
S
K
E
S
N
Y
F
Y
S
S
T
Q
N
N
E
Site 102
T757
S
N
Y
F
Y
S
S
T
Q
N
N
E
T
E
L
Site 103
T762
S
S
T
Q
N
N
E
T
E
L
T
S
P
I
L
Site 104
T765
Q
N
N
E
T
E
L
T
S
P
I
L
L
P
D
Site 105
S766
N
N
E
T
E
L
T
S
P
I
L
L
P
D
L
Site 106
T778
P
D
L
Q
I
K
I
T
N
I
F
R
P
G
F
Site 107
S786
N
I
F
R
P
G
F
S
P
T
A
D
S
L
A
Site 108
S791
G
F
S
P
T
A
D
S
L
A
L
K
D
S
F
Site 109
S797
D
S
L
A
L
K
D
S
F
C
T
H
V
T
E
Site 110
Y823
E
I
L
G
F
D
I
Y
S
Q
P
F
G
E
N
Site 111
Y833
P
F
G
E
N
A
D
Y
P
C
E
D
K
V
D
Site 112
S846
V
D
N
I
R
Q
E
S
G
P
V
S
N
S
E
Site 113
S850
R
Q
E
S
G
P
V
S
N
S
E
I
S
L
S
Site 114
S852
E
S
G
P
V
S
N
S
E
I
S
L
S
F
D
Site 115
S855
P
V
S
N
S
E
I
S
L
S
F
D
L
S
R
Site 116
S857
S
N
S
E
I
S
L
S
F
D
L
S
R
N
T
Site 117
S861
I
S
L
S
F
D
L
S
R
N
T
D
V
N
H
Site 118
T864
S
F
D
L
S
R
N
T
D
V
N
H
T
S
E
Site 119
S870
N
T
D
V
N
H
T
S
E
N
Q
N
S
E
S
Site 120
S875
H
T
S
E
N
Q
N
S
E
S
L
F
T
E
P
Site 121
S877
S
E
N
Q
N
S
E
S
L
F
T
E
P
S
N
Site 122
T880
Q
N
S
E
S
L
F
T
E
P
S
N
V
T
T
Site 123
S883
E
S
L
F
T
E
P
S
N
V
T
T
I
D
D
Site 124
T887
T
E
P
S
N
V
T
T
I
D
D
G
S
R
C
Site 125
S892
V
T
T
I
D
D
G
S
R
C
F
F
T
K
S
Site 126
Y903
F
T
K
S
K
T
D
Y
N
D
T
K
N
K
K
Site 127
S917
K
E
V
E
S
R
I
S
K
R
K
L
H
I
S
Site 128
S924
S
K
R
K
L
H
I
S
S
R
D
Q
N
I
P
Site 129
Y941
D
L
R
R
H
K
I
Y
G
R
K
R
R
L
T
Site 130
T948
Y
G
R
K
R
R
L
T
S
Q
D
S
S
E
C
Site 131
S949
G
R
K
R
R
L
T
S
Q
D
S
S
E
C
F
Site 132
S952
R
R
L
T
S
Q
D
S
S
E
C
F
S
S
L
Site 133
S953
R
L
T
S
Q
D
S
S
E
C
F
S
S
L
S
Site 134
S957
Q
D
S
S
E
C
F
S
S
L
S
Q
G
R
I
Site 135
S958
D
S
S
E
C
F
S
S
L
S
Q
G
R
I
K
Site 136
S960
S
E
C
F
S
S
L
S
Q
G
R
I
K
T
F
Site 137
T966
L
S
Q
G
R
I
K
T
F
S
Q
S
E
K
H
Site 138
S968
Q
G
R
I
K
T
F
S
Q
S
E
K
H
I
K
Site 139
S970
R
I
K
T
F
S
Q
S
E
K
H
I
K
S
V
Site 140
S976
Q
S
E
K
H
I
K
S
V
L
N
I
L
S
D
Site 141
S986
N
I
L
S
D
E
A
S
L
C
K
S
K
C
L
Site 142
S990
D
E
A
S
L
C
K
S
K
C
L
S
R
K
L
Site 143
S994
L
C
K
S
K
C
L
S
R
K
L
D
K
A
V
Site 144
T1013
K
A
H
R
R
V
H
T
S
L
Q
L
I
T
K
Site 145
S1014
A
H
R
R
V
H
T
S
L
Q
L
I
T
K
V
Site 146
T1019
H
T
S
L
Q
L
I
T
K
V
G
E
E
R
K
Site 147
S1032
R
K
G
P
L
P
K
S
Y
A
V
I
C
N
N
Site 148
Y1033
K
G
P
L
P
K
S
Y
A
V
I
C
N
N
F
Site 149
Y1049
E
S
C
D
L
Q
G
Y
S
S
V
S
Q
R
K
Site 150
S1051
C
D
L
Q
G
Y
S
S
V
S
Q
R
K
Y
Y
Site 151
S1053
L
Q
G
Y
S
S
V
S
Q
R
K
Y
Y
S
T
Site 152
Y1057
S
S
V
S
Q
R
K
Y
Y
S
T
K
H
F
S
Site 153
Y1058
S
V
S
Q
R
K
Y
Y
S
T
K
H
F
S
S
Site 154
S1059
V
S
Q
R
K
Y
Y
S
T
K
H
F
S
S
K
Site 155
T1060
S
Q
R
K
Y
Y
S
T
K
H
F
S
S
K
R
Site 156
S1064
Y
Y
S
T
K
H
F
S
S
K
R
K
Y
D
K
Site 157
S1065
Y
S
T
K
H
F
S
S
K
R
K
Y
D
K
R
Site 158
Y1069
H
F
S
S
K
R
K
Y
D
K
R
R
K
K
R
Site 159
S1083
R
A
P
K
A
D
I
S
K
S
L
T
H
V
S
Site 160
S1085
P
K
A
D
I
S
K
S
L
T
H
V
S
K
H
Site 161
T1087
A
D
I
S
K
S
L
T
H
V
S
K
H
K
S
Site 162
S1090
S
K
S
L
T
H
V
S
K
H
K
S
Y
K
T
Site 163
S1094
T
H
V
S
K
H
K
S
Y
K
T
S
G
E
K
Site 164
S1098
K
H
K
S
Y
K
T
S
G
E
K
K
C
L
S
Site 165
S1105
S
G
E
K
K
C
L
S
R
K
S
M
A
S
S
Site 166
S1108
K
K
C
L
S
R
K
S
M
A
S
S
V
S
K
Site 167
S1111
L
S
R
K
S
M
A
S
S
V
S
K
S
H
P
Site 168
S1112
S
R
K
S
M
A
S
S
V
S
K
S
H
P
T
Site 169
S1114
K
S
M
A
S
S
V
S
K
S
H
P
T
T
S
Site 170
S1116
M
A
S
S
V
S
K
S
H
P
T
T
S
H
M
Site 171
T1120
V
S
K
S
H
P
T
T
S
H
M
G
E
F
C
Site 172
S1134
C
N
Q
E
H
P
E
S
Q
L
P
V
S
S
T
Site 173
S1139
P
E
S
Q
L
P
V
S
S
T
S
Q
S
T
S
Site 174
S1140
E
S
Q
L
P
V
S
S
T
S
Q
S
T
S
Q
Site 175
T1141
S
Q
L
P
V
S
S
T
S
Q
S
T
S
Q
S
Site 176
S1142
Q
L
P
V
S
S
T
S
Q
S
T
S
Q
S
V
Site 177
S1144
P
V
S
S
T
S
Q
S
T
S
Q
S
V
Y
Y
Site 178
S1146
S
S
T
S
Q
S
T
S
Q
S
V
Y
Y
N
S
Site 179
S1148
T
S
Q
S
T
S
Q
S
V
Y
Y
N
S
S
V
Site 180
Y1150
Q
S
T
S
Q
S
V
Y
Y
N
S
S
V
S
N
Site 181
Y1151
S
T
S
Q
S
V
Y
Y
N
S
S
V
S
N
P
Site 182
S1153
S
Q
S
V
Y
Y
N
S
S
V
S
N
P
S
L
Site 183
S1154
Q
S
V
Y
Y
N
S
S
V
S
N
P
S
L
S
Site 184
S1156
V
Y
Y
N
S
S
V
S
N
P
S
L
S
E
E
Site 185
S1159
N
S
S
V
S
N
P
S
L
S
E
E
H
Q
P
Site 186
S1161
S
V
S
N
P
S
L
S
E
E
H
Q
P
F
S
Site 187
S1168
S
E
E
H
Q
P
F
S
G
K
T
A
Y
L
F
Site 188
Y1173
P
F
S
G
K
T
A
Y
L
F
S
P
D
H
S
Site 189
S1176
G
K
T
A
Y
L
F
S
P
D
H
S
D
E
K
Site 190
S1180
Y
L
F
S
P
D
H
S
D
E
K
L
I
E
K
Site 191
T1193
E
K
E
N
Q
I
D
T
A
F
L
S
S
T
S
Site 192
S1197
Q
I
D
T
A
F
L
S
S
T
S
K
Y
E
K
Site 193
Y1202
F
L
S
S
T
S
K
Y
E
K
L
E
K
H
S
Site 194
S1232
A
N
E
V
I
N
E
S
N
S
V
S
L
S
C
Site 195
S1234
E
V
I
N
E
S
N
S
V
S
L
S
C
I
K
Site 196
S1236
I
N
E
S
N
S
V
S
L
S
C
I
K
E
N
Site 197
S1238
E
S
N
S
V
S
L
S
C
I
K
E
N
I
N
Site 198
Y1283
K
H
F
L
N
D
L
Y
Q
Q
G
N
L
I
L
Site 199
S1291
Q
Q
G
N
L
I
L
S
D
C
K
R
N
L
E
Site 200
T1302
R
N
L
E
V
K
W
T
D
P
I
E
R
P
K
Site 201
S1345
S
A
A
A
V
T
D
S
E
G
E
S
S
K
S
Site 202
S1349
V
T
D
S
E
G
E
S
S
K
S
Y
L
D
K
Site 203
S1350
T
D
S
E
G
E
S
S
K
S
Y
L
D
K
Q
Site 204
S1352
S
E
G
E
S
S
K
S
Y
L
D
K
Q
R
I
Site 205
Y1353
E
G
E
S
S
K
S
Y
L
D
K
Q
R
I
L
Site 206
T1361
L
D
K
Q
R
I
L
T
V
D
S
F
A
A
S
Site 207
S1368
T
V
D
S
F
A
A
S
S
T
V
P
H
C
E
Site 208
T1370
D
S
F
A
A
S
S
T
V
P
H
C
E
Q
S
Site 209
S1377
T
V
P
H
C
E
Q
S
C
R
E
K
E
L
L
Site 210
T1386
R
E
K
E
L
L
K
T
E
Q
C
S
S
G
N
Site 211
S1391
L
K
T
E
Q
C
S
S
G
N
C
L
H
T
D
Site 212
T1397
S
S
G
N
C
L
H
T
D
G
N
E
T
N
V
Site 213
T1405
D
G
N
E
T
N
V
T
E
N
Y
E
L
D
V
Site 214
S1421
S
G
T
E
E
D
K
S
Y
G
E
N
I
V
E
Site 215
Y1422
G
T
E
E
D
K
S
Y
G
E
N
I
V
E
L
Site 216
S1430
G
E
N
I
V
E
L
S
S
S
D
S
S
L
L
Site 217
S1434
V
E
L
S
S
S
D
S
S
L
L
L
R
D
N
Site 218
S1435
E
L
S
S
S
D
S
S
L
L
L
R
D
N
V
Site 219
S1447
D
N
V
K
G
S
S
S
E
T
C
I
V
K
K
Site 220
T1449
V
K
G
S
S
S
E
T
C
I
V
K
K
D
T
Site 221
T1456
T
C
I
V
K
K
D
T
E
D
R
I
T
W
K
Site 222
T1461
K
D
T
E
D
R
I
T
W
K
V
K
Q
A
E
Site 223
S1473
Q
A
E
K
A
K
D
S
V
Y
K
R
S
M
T
Site 224
Y1475
E
K
A
K
D
S
V
Y
K
R
S
M
T
E
G
Site 225
S1478
K
D
S
V
Y
K
R
S
M
T
E
G
S
T
V
Site 226
T1480
S
V
Y
K
R
S
M
T
E
G
S
T
V
N
T
Site 227
T1484
R
S
M
T
E
G
S
T
V
N
T
E
Y
K
N
Site 228
T1487
T
E
G
S
T
V
N
T
E
Y
K
N
Q
K
N
Site 229
Y1489
G
S
T
V
N
T
E
Y
K
N
Q
K
N
Q
I
Site 230
T1508
C
L
N
E
K
I
I
T
T
N
L
I
D
S
H
Site 231
T1509
L
N
E
K
I
I
T
T
N
L
I
D
S
H
L
Site 232
S1514
I
T
T
N
L
I
D
S
H
L
S
T
K
N
T
Site 233
S1517
N
L
I
D
S
H
L
S
T
K
N
T
T
T
E
Site 234
T1518
L
I
D
S
H
L
S
T
K
N
T
T
T
E
S
Site 235
T1521
S
H
L
S
T
K
N
T
T
T
E
S
V
P
L
Site 236
T1522
H
L
S
T
K
N
T
T
T
E
S
V
P
L
K
Site 237
S1525
T
K
N
T
T
T
E
S
V
P
L
K
N
T
V
Site 238
T1531
E
S
V
P
L
K
N
T
V
S
N
P
L
N
K
Site 239
S1548
K
K
G
E
I
K
V
S
K
D
S
Q
S
D
L
Site 240
S1551
E
I
K
V
S
K
D
S
Q
S
D
L
T
L
H
Site 241
S1553
K
V
S
K
D
S
Q
S
D
L
T
L
H
S
E
Site 242
T1556
K
D
S
Q
S
D
L
T
L
H
S
E
I
A
Y
Site 243
S1559
Q
S
D
L
T
L
H
S
E
I
A
Y
I
S
K
Site 244
T1589
S
E
T
C
K
V
P
T
L
L
K
K
P
A
S
Site 245
S1596
T
L
L
K
K
P
A
S
Y
V
S
D
F
K
E
Site 246
Y1597
L
L
K
K
P
A
S
Y
V
S
D
F
K
E
K
Site 247
S1599
K
K
P
A
S
Y
V
S
D
F
K
E
K
H
C
Site 248
S1628
L
Q
R
A
D
E
A
S
S
L
Q
I
L
Q
E
Site 249
S1658
F
E
R
K
Q
E
C
S
V
E
Q
I
L
I
S
Site 250
T1715
R
H
L
E
G
E
P
T
L
R
S
L
L
W
Y
Site 251
Y1722
T
L
R
S
L
L
W
Y
D
E
T
L
Y
A
E
Site 252
Y1727
L
W
Y
D
E
T
L
Y
A
E
L
L
G
K
P
Site 253
Y1744
F
Q
Q
Q
S
N
F
Y
P
G
F
Q
G
R
L
Site 254
Y1753
G
F
Q
G
R
L
K
Y
N
A
F
C
E
L
Q
Site 255
Y1762
A
F
C
E
L
Q
T
Y
H
D
Q
L
V
E
L
Site 256
S1779
E
T
K
R
E
K
N
S
Y
Y
V
F
L
K
Y
Site 257
Y1780
T
K
R
E
K
N
S
Y
Y
V
F
L
K
Y
K
Site 258
Y1781
K
R
E
K
N
S
Y
Y
V
F
L
K
Y
K
R
Site 259
Y1786
S
Y
Y
V
F
L
K
Y
K
R
Q
V
N
E
C
Site 260
S1842
L
I
N
V
C
G
D
S
P
K
V
H
S
Y
P
Site 261
S1847
G
D
S
P
K
V
H
S
Y
P
G
K
Q
D
H
Site 262
Y1848
D
S
P
K
V
H
S
Y
P
G
K
Q
D
H
L
Site 263
T1901
N
L
V
W
K
E
R
T
Q
S
F
S
K
K
Y
Site 264
S1903
V
W
K
E
R
T
Q
S
F
S
K
K
Y
S
Q
Site 265
S1905
K
E
R
T
Q
S
F
S
K
K
Y
S
Q
K
K
Site 266
S1909
Q
S
F
S
K
K
Y
S
Q
K
K
D
E
E
R
Site 267
T1934
K
L
Q
K
I
Y
D
T
L
S
K
D
L
N
N
Site 268
S1936
Q
K
I
Y
D
T
L
S
K
D
L
N
N
E
P
Site 269
S1945
D
L
N
N
E
P
I
S
P
I
G
L
E
E
D
Site 270
T1953
P
I
G
L
E
E
D
T
I
I
A
S
R
K
S
Site 271
S1960
T
I
I
A
S
R
K
S
D
H
P
I
N
E
A
Site 272
S1970
P
I
N
E
A
T
I
S
I
E
N
S
K
F
N
Site 273
S1974
A
T
I
S
I
E
N
S
K
F
N
S
N
L
L
Site 274
S1978
I
E
N
S
K
F
N
S
N
L
L
A
H
P
D
Site 275
T2008
L
K
K
L
Q
D
L
T
L
R
C
T
D
H
L
Site 276
T2012
Q
D
L
T
L
R
C
T
D
H
L
E
I
L
K
Site 277
Y2021
H
L
E
I
L
K
K
Y
F
Q
M
L
Q
D
N
Site 278
S2078
T
I
H
F
L
K
N
S
I
A
K
K
L
D
K
Site 279
S2111
Q
C
Q
E
K
M
A
S
F
S
F
L
K
D
N
Site 280
S2113
Q
E
K
M
A
S
F
S
F
L
K
D
N
S
T
Site 281
T2120
S
F
L
K
D
N
S
T
D
V
C
L
W
K
V
Site 282
S2133
K
V
I
E
T
A
V
S
E
L
K
K
D
L
D
Site 283
Y2145
D
L
D
I
I
C
K
Y
N
E
A
V
N
C
S
Site 284
S2159
S
Y
A
I
H
L
L
S
R
E
L
Q
E
L
S
Site 285
S2166
S
R
E
L
Q
E
L
S
E
I
K
K
L
L
K
Site 286
S2175
I
K
K
L
L
K
K
S
K
Y
F
I
S
T
Y
Site 287
Y2177
K
L
L
K
K
S
K
Y
F
I
S
T
Y
I
D
Site 288
S2180
K
K
S
K
Y
F
I
S
T
Y
I
D
F
V
P
Site 289
T2181
K
S
K
Y
F
I
S
T
Y
I
D
F
V
P
Y
Site 290
T2197
A
S
I
N
Y
G
S
T
V
T
E
L
E
Y
N
Site 291
Y2203
S
T
V
T
E
L
E
Y
N
Y
N
Q
F
S
T
Site 292
Y2205
V
T
E
L
E
Y
N
Y
N
Q
F
S
T
L
L
Site 293
S2217
T
L
L
K
N
V
M
S
A
P
R
K
D
L
G
Site 294
S2289
G
E
N
N
N
K
F
S
I
S
T
M
L
P
P
Site 295
S2291
N
N
N
K
F
S
I
S
T
M
L
P
P
V
S
Site 296
S2298
S
T
M
L
P
P
V
S
E
C
I
N
K
N
I
Site 297
S2306
E
C
I
N
K
N
I
S
N
S
S
K
K
R
P
Site 298
S2308
I
N
K
N
I
S
N
S
S
K
K
R
P
S
T
Site 299
S2309
N
K
N
I
S
N
S
S
K
K
R
P
S
T
V
Site 300
S2314
N
S
S
K
K
R
P
S
T
V
D
K
C
E
D
Site 301
T2315
S
S
K
K
R
P
S
T
V
D
K
C
E
D
S
Site 302
S2322
T
V
D
K
C
E
D
S
Q
E
Q
Q
Q
D
T
Site 303
T2329
S
Q
E
Q
Q
Q
D
T
T
V
S
S
C
K
K
Site 304
T2330
Q
E
Q
Q
Q
D
T
T
V
S
S
C
K
K
L
Site 305
S2332
Q
Q
Q
D
T
T
V
S
S
C
K
K
L
K
V
Site 306
T2345
K
V
D
M
K
D
V
T
K
I
N
R
E
K
A
Site 307
T2359
A
T
F
K
H
P
R
T
T
G
S
H
P
K
S
Site 308
T2360
T
F
K
H
P
R
T
T
G
S
H
P
K
S
E
Site 309
S2362
K
H
P
R
T
T
G
S
H
P
K
S
E
N
K
Site 310
S2366
T
T
G
S
H
P
K
S
E
N
K
I
V
P
S
Site 311
S2373
S
E
N
K
I
V
P
S
S
C
D
S
L
K
R
Site 312
S2374
E
N
K
I
V
P
S
S
C
D
S
L
K
R
N
Site 313
S2377
I
V
P
S
S
C
D
S
L
K
R
N
H
L
T
Site 314
T2384
S
L
K
R
N
H
L
T
P
K
K
V
E
M
Q
Site 315
S2393
K
K
V
E
M
Q
R
S
L
P
G
S
L
L
P
Site 316
S2397
M
Q
R
S
L
P
G
S
L
L
P
L
E
N
P
Site 317
T2407
P
L
E
N
P
K
D
T
C
A
S
K
S
E
S
Site 318
S2410
N
P
K
D
T
C
A
S
K
S
E
S
K
I
D
Site 319
S2412
K
D
T
C
A
S
K
S
E
S
K
I
D
L
T
Site 320
S2414
T
C
A
S
K
S
E
S
K
I
D
L
T
V
S
Site 321
T2419
S
E
S
K
I
D
L
T
V
S
S
D
H
F
S
Site 322
S2421
S
K
I
D
L
T
V
S
S
D
H
F
S
G
Q
Site 323
S2422
K
I
D
L
T
V
S
S
D
H
F
S
G
Q
Q
Site 324
S2426
T
V
S
S
D
H
F
S
G
Q
Q
E
N
L
N
Site 325
S2434
G
Q
Q
E
N
L
N
S
M
K
K
R
N
V
N
Site 326
S2443
K
K
R
N
V
N
F
S
A
A
E
T
K
S
D
Site 327
T2447
V
N
F
S
A
A
E
T
K
S
D
K
K
D
C
Site 328
S2449
F
S
A
A
E
T
K
S
D
K
K
D
C
A
A
Site 329
T2468
D
Q
K
S
V
H
G
T
F
S
P
D
H
G
T
Site 330
S2470
K
S
V
H
G
T
F
S
P
D
H
G
T
L
L
Site 331
T2475
T
F
S
P
D
H
G
T
L
L
Q
K
F
L
K
Site 332
S2484
L
Q
K
F
L
K
N
S
P
D
P
T
Q
K
S
Site 333
T2488
L
K
N
S
P
D
P
T
Q
K
S
C
L
S
D
Site 334
S2491
S
P
D
P
T
Q
K
S
C
L
S
D
I
N
P
Site 335
S2494
P
T
Q
K
S
C
L
S
D
I
N
P
E
T
D
Site 336
T2500
L
S
D
I
N
P
E
T
D
V
S
L
V
P
D
Site 337
T2531
P
D
L
E
M
N
D
T
V
F
E
L
Q
D
N
Site 338
S2543
Q
D
N
D
I
V
N
S
S
I
K
N
S
S
C
Site 339
S2544
D
N
D
I
V
N
S
S
I
K
N
S
S
C
M
Site 340
S2548
V
N
S
S
I
K
N
S
S
C
M
T
S
P
E
Site 341
S2549
N
S
S
I
K
N
S
S
C
M
T
S
P
E
P
Site 342
S2553
K
N
S
S
C
M
T
S
P
E
P
I
C
I
Q
Site 343
Y2582
E
T
E
S
E
D
K
Y
M
K
D
T
L
N
P
Site 344
T2586
E
D
K
Y
M
K
D
T
L
N
P
N
T
V
H
Site 345
T2591
K
D
T
L
N
P
N
T
V
H
T
F
G
A
S
Site 346
T2594
L
N
P
N
T
V
H
T
F
G
A
S
G
H
I
Site 347
S2612
V
N
Q
G
A
E
Y
S
L
S
E
Q
Q
N
D
Site 348
S2614
Q
G
A
E
Y
S
L
S
E
Q
Q
N
D
K
N
Site 349
T2644
P
Q
S
A
C
N
P
T
Y
N
S
S
E
H
L
Site 350
Y2645
Q
S
A
C
N
P
T
Y
N
S
S
E
H
L
F
Site 351
S2647
A
C
N
P
T
Y
N
S
S
E
H
L
F
G
T
Site 352
S2648
C
N
P
T
Y
N
S
S
E
H
L
F
G
T
S
Site 353
T2654
S
S
E
H
L
F
G
T
S
Y
P
Y
S
A
W
Site 354
Y2656
E
H
L
F
G
T
S
Y
P
Y
S
A
W
C
V
Site 355
Y2664
P
Y
S
A
W
C
V
Y
Q
Y
S
N
S
N
G
Site 356
Y2666
S
A
W
C
V
Y
Q
Y
S
N
S
N
G
N
A
Site 357
T2677
N
G
N
A
I
T
Q
T
Y
Q
G
I
T
S
Y
Site 358
Y2678
G
N
A
I
T
Q
T
Y
Q
G
I
T
S
Y
E
Site 359
S2683
Q
T
Y
Q
G
I
T
S
Y
E
V
Q
P
S
P
Site 360
Y2684
T
Y
Q
G
I
T
S
Y
E
V
Q
P
S
P
S
Site 361
S2689
T
S
Y
E
V
Q
P
S
P
S
G
L
L
T
T
Site 362
S2706
S
T
A
Q
G
T
H
S
N
L
L
Y
S
Q
Y
Site 363
Y2710
G
T
H
S
N
L
L
Y
S
Q
Y
F
T
Y
F
Site 364
Y2713
S
N
L
L
Y
S
Q
Y
F
T
Y
F
A
G
E
Site 365
T2715
L
L
Y
S
Q
Y
F
T
Y
F
A
G
E
P
Q
Site 366
Y2716
L
Y
S
Q
Y
F
T
Y
F
A
G
E
P
Q
A
Site 367
S2735
P
V
N
G
Y
F
Q
S
Q
I
P
A
S
N
F
Site 368
S2740
F
Q
S
Q
I
P
A
S
N
F
R
Q
P
I
F
Site 369
S2748
N
F
R
Q
P
I
F
S
Q
Y
A
S
H
Q
P
Site 370
Y2750
R
Q
P
I
F
S
Q
Y
A
S
H
Q
P
L
P
Site 371
S2752
P
I
F
S
Q
Y
A
S
H
Q
P
L
P
Q
A
Site 372
Y2761
Q
P
L
P
Q
A
T
Y
P
Y
L
P
N
R
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation