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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BBS2
Full Name:
Bardet-Biedl syndrome 2 protein
Alias:
Bardet-Biedl syndrome 2; BBS
Type:
Cell development/differentiation
Mass (Da):
79852
Number AA:
721
UniProt ID:
Q9BXC9
International Prot ID:
IPI00306961
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034464
GO:0060170
GO:0005932
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030534
GO:0048854
GO:0021987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
R
M
V
A
I
G
R
Y
D
G
T
H
P
C
L
Site 2
S53
H
T
R
N
Q
H
V
S
A
S
R
V
F
Q
S
Site 3
S55
R
N
Q
H
V
S
A
S
R
V
F
Q
S
P
L
Site 4
S60
S
A
S
R
V
F
Q
S
P
L
E
S
D
V
S
Site 5
S67
S
P
L
E
S
D
V
S
L
L
N
I
N
Q
A
Site 6
Y106
N
L
L
A
Y
D
V
Y
N
N
S
D
L
F
Y
Site 7
Y113
Y
N
N
S
D
L
F
Y
R
E
V
A
D
G
A
Site 8
T157
E
G
S
D
L
F
W
T
V
T
G
D
N
V
N
Site 9
T159
S
D
L
F
W
T
V
T
G
D
N
V
N
S
L
Site 10
Y219
M
Y
G
S
R
F
G
Y
A
L
S
N
G
T
V
Site 11
Y229
S
N
G
T
V
G
V
Y
D
K
T
S
R
Y
W
Site 12
T232
T
V
G
V
Y
D
K
T
S
R
Y
W
R
I
K
Site 13
Y235
V
Y
D
K
T
S
R
Y
W
R
I
K
S
K
N
Site 14
S246
K
S
K
N
H
A
M
S
I
H
A
F
D
L
N
Site 15
T262
D
G
V
N
E
L
I
T
G
W
S
N
G
K
V
Site 16
S273
N
G
K
V
D
A
R
S
D
R
T
G
E
V
I
Site 17
Y297
A
G
V
V
E
G
D
Y
R
M
D
G
H
I
Q
Site 18
Y317
V
D
G
E
I
R
G
Y
L
P
G
T
A
E
M
Site 19
T321
I
R
G
Y
L
P
G
T
A
E
M
R
G
N
L
Site 20
S332
R
G
N
L
M
D
T
S
A
E
Q
D
L
I
R
Site 21
S342
Q
D
L
I
R
E
L
S
Q
K
K
Q
N
L
L
Site 22
Y355
L
L
L
E
L
R
N
Y
E
E
N
A
K
A
E
Site 23
S365
N
A
K
A
E
L
A
S
P
L
N
E
A
D
G
Site 24
T385
P
A
N
T
R
L
H
T
T
L
S
V
S
L
G
Site 25
T386
A
N
T
R
L
H
T
T
L
S
V
S
L
G
N
Site 26
S388
T
R
L
H
T
T
L
S
V
S
L
G
N
E
T
Site 27
S390
L
H
T
T
L
S
V
S
L
G
N
E
T
Q
T
Site 28
S405
A
H
T
E
L
R
I
S
T
S
N
D
T
I
I
Site 29
T406
H
T
E
L
R
I
S
T
S
N
D
T
I
I
R
Site 30
S407
T
E
L
R
I
S
T
S
N
D
T
I
I
R
A
Site 31
S427
E
G
I
F
T
G
E
S
H
V
V
H
P
S
I
Site 32
S433
E
S
H
V
V
H
P
S
I
H
N
L
S
S
S
Site 33
S466
A
F
V
G
Y
R
S
S
T
Q
F
H
V
F
E
Site 34
T467
F
V
G
Y
R
S
S
T
Q
F
H
V
F
E
S
Site 35
S474
T
Q
F
H
V
F
E
S
T
R
Q
L
P
R
F
Site 36
S482
T
R
Q
L
P
R
F
S
M
Y
A
L
T
S
L
Site 37
Y484
Q
L
P
R
F
S
M
Y
A
L
T
S
L
D
P
Site 38
S488
F
S
M
Y
A
L
T
S
L
D
P
A
S
E
P
Site 39
S493
L
T
S
L
D
P
A
S
E
P
I
S
Y
V
N
Site 40
T524
N
F
L
L
P
E
D
T
H
I
Q
N
A
P
F
Site 41
T555
I
K
L
S
G
E
I
T
I
N
T
D
D
I
D
Site 42
T558
S
G
E
I
T
I
N
T
D
D
I
D
L
A
G
Site 43
Y589
V
E
A
D
F
P
V
Y
F
E
E
L
R
K
V
Site 44
Y603
V
L
V
K
V
D
E
Y
H
S
V
H
Q
K
L
Site 45
S605
V
K
V
D
E
Y
H
S
V
H
Q
K
L
S
A
Site 46
S611
H
S
V
H
Q
K
L
S
A
D
M
A
D
H
S
Site 47
S618
S
A
D
M
A
D
H
S
N
L
I
R
S
L
L
Site 48
T639
R
L
M
R
D
M
K
T
M
K
S
R
Y
M
E
Site 49
Y644
M
K
T
M
K
S
R
Y
M
E
L
Y
D
L
N
Site 50
Y648
K
S
R
Y
M
E
L
Y
D
L
N
R
D
L
L
Site 51
Y658
N
R
D
L
L
N
G
Y
K
I
R
C
N
N
H
Site 52
T666
K
I
R
C
N
N
H
T
E
L
L
G
N
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation