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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OSBPL10
Full Name:
Oxysterol-binding protein-related protein 10
Alias:
ORP10; ORP-10; OSB10; OSBP9; OSBP-related protein 10; Oxysterol binding protein-like 10
Type:
Lipid binding protein
Mass (Da):
83970
Number AA:
764
UniProt ID:
Q9BXB5
International Prot ID:
IPI00032971
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006869
GO:0008202
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
E
R
A
V
Q
G
T
D
G
G
G
G
S
N
Site 2
S14
G
T
D
G
G
G
G
S
N
S
S
S
R
S
S
Site 3
S16
D
G
G
G
G
S
N
S
S
S
R
S
S
S
R
Site 4
S17
G
G
G
G
S
N
S
S
S
R
S
S
S
R
A
Site 5
S18
G
G
G
S
N
S
S
S
R
S
S
S
R
A
T
Site 6
S20
G
S
N
S
S
S
R
S
S
S
R
A
T
S
A
Site 7
S21
S
N
S
S
S
R
S
S
S
R
A
T
S
A
G
Site 8
S22
N
S
S
S
R
S
S
S
R
A
T
S
A
G
S
Site 9
T25
S
R
S
S
S
R
A
T
S
A
G
S
S
P
S
Site 10
S26
R
S
S
S
R
A
T
S
A
G
S
S
P
S
C
Site 11
S29
S
R
A
T
S
A
G
S
S
P
S
C
S
L
A
Site 12
S30
R
A
T
S
A
G
S
S
P
S
C
S
L
A
G
Site 13
S32
T
S
A
G
S
S
P
S
C
S
L
A
G
R
G
Site 14
S34
A
G
S
S
P
S
C
S
L
A
G
R
G
V
S
Site 15
S41
S
L
A
G
R
G
V
S
S
R
S
A
A
A
G
Site 16
S44
G
R
G
V
S
S
R
S
A
A
A
G
L
G
G
Site 17
S54
A
G
L
G
G
G
G
S
R
S
S
P
G
S
V
Site 18
S56
L
G
G
G
G
S
R
S
S
P
G
S
V
A
A
Site 19
S57
G
G
G
G
S
R
S
S
P
G
S
V
A
A
S
Site 20
S60
G
S
R
S
S
P
G
S
V
A
A
S
P
S
G
Site 21
S64
S
P
G
S
V
A
A
S
P
S
G
G
G
G
R
Site 22
S66
G
S
V
A
A
S
P
S
G
G
G
G
R
R
R
Site 23
Y84
L
E
G
V
L
S
K
Y
T
N
L
L
Q
G
W
Site 24
Y95
L
Q
G
W
Q
N
R
Y
F
V
L
D
F
E
A
Site 25
Y107
F
E
A
G
I
L
Q
Y
F
V
N
E
Q
S
K
Site 26
Y172
Q
L
R
A
C
A
K
Y
H
M
E
M
N
S
K
Site 27
S178
K
Y
H
M
E
M
N
S
K
S
A
P
S
S
R
Site 28
S180
H
M
E
M
N
S
K
S
A
P
S
S
R
S
R
Site 29
S183
M
N
S
K
S
A
P
S
S
R
S
R
S
L
T
Site 30
S184
N
S
K
S
A
P
S
S
R
S
R
S
L
T
L
Site 31
S186
K
S
A
P
S
S
R
S
R
S
L
T
L
L
P
Site 32
S188
A
P
S
S
R
S
R
S
L
T
L
L
P
H
G
Site 33
T190
S
S
R
S
R
S
L
T
L
L
P
H
G
T
P
Site 34
T196
L
T
L
L
P
H
G
T
P
N
S
A
S
P
C
Site 35
S199
L
P
H
G
T
P
N
S
A
S
P
C
S
Q
R
Site 36
S201
H
G
T
P
N
S
A
S
P
C
S
Q
R
H
L
Site 37
S204
P
N
S
A
S
P
C
S
Q
R
H
L
S
V
G
Site 38
S209
P
C
S
Q
R
H
L
S
V
G
A
P
G
V
V
Site 39
T219
A
P
G
V
V
T
I
T
H
H
K
S
P
A
A
Site 40
S223
V
T
I
T
H
H
K
S
P
A
A
A
R
R
A
Site 41
S232
A
A
A
R
R
A
K
S
Q
Y
S
G
Q
L
H
Site 42
Y234
A
R
R
A
K
S
Q
Y
S
G
Q
L
H
E
V
Site 43
S307
V
H
Q
A
G
Q
P
S
Q
K
P
G
A
S
E
Site 44
S322
N
I
L
G
W
H
G
S
K
S
H
S
T
E
Q
Site 45
S324
L
G
W
H
G
S
K
S
H
S
T
E
Q
L
K
Site 46
S326
W
H
G
S
K
S
H
S
T
E
Q
L
K
N
G
Site 47
S337
L
K
N
G
T
L
G
S
L
P
S
A
S
A
N
Site 48
S353
T
W
A
I
L
P
N
S
A
E
D
E
Q
T
S
Site 49
T359
N
S
A
E
D
E
Q
T
S
Q
P
E
P
E
P
Site 50
S368
Q
P
E
P
E
P
N
S
G
S
E
L
V
L
S
Site 51
S370
E
P
E
P
N
S
G
S
E
L
V
L
S
E
D
Site 52
S375
S
G
S
E
L
V
L
S
E
D
E
K
S
D
N
Site 53
S380
V
L
S
E
D
E
K
S
D
N
E
D
K
E
E
Site 54
Y479
G
A
L
A
K
K
P
Y
N
P
I
I
G
E
T
Site 55
T503
D
R
V
K
P
K
R
T
A
S
R
S
P
A
S
Site 56
S505
V
K
P
K
R
T
A
S
R
S
P
A
S
C
H
Site 57
S507
P
K
R
T
A
S
R
S
P
A
S
C
H
E
H
Site 58
S510
T
A
S
R
S
P
A
S
C
H
E
H
P
M
A
Site 59
S521
H
P
M
A
D
D
P
S
K
S
Y
K
L
R
F
Site 60
S523
M
A
D
D
P
S
K
S
Y
K
L
R
F
V
A
Site 61
S534
R
F
V
A
E
Q
V
S
H
H
P
P
I
S
C
Site 62
T555
E
K
R
L
C
V
N
T
H
V
W
T
K
S
K
Site 63
S561
N
T
H
V
W
T
K
S
K
F
M
G
M
S
V
Site 64
T590
H
G
E
E
Y
V
F
T
L
P
S
A
Y
A
R
Site 65
T623
A
K
T
G
Y
S
A
T
V
I
F
H
T
K
P
Site 66
Y632
I
F
H
T
K
P
F
Y
G
G
K
V
H
R
V
Site 67
T640
G
G
K
V
H
R
V
T
A
E
V
K
H
N
P
Site 68
T650
V
K
H
N
P
T
N
T
I
V
C
K
A
H
G
Site 69
T662
A
H
G
E
W
N
G
T
L
E
F
T
Y
N
N
Site 70
Y667
N
G
T
L
E
F
T
Y
N
N
G
E
T
K
V
Site 71
T678
E
T
K
V
I
D
T
T
T
L
P
V
Y
P
K
Site 72
T679
T
K
V
I
D
T
T
T
L
P
V
Y
P
K
K
Site 73
Y683
D
T
T
T
L
P
V
Y
P
K
K
I
R
P
L
Site 74
T706
R
N
L
W
R
E
V
T
R
Y
L
R
L
G
D
Site 75
Y708
L
W
R
E
V
T
R
Y
L
R
L
G
D
I
D
Site 76
T718
L
G
D
I
D
A
A
T
E
Q
K
R
H
L
E
Site 77
T740
R
K
R
E
N
L
R
T
P
W
K
P
K
Y
F
Site 78
Y746
R
T
P
W
K
P
K
Y
F
I
Q
E
G
D
G
Site 79
Y756
Q
E
G
D
G
W
V
Y
F
N
P
L
W
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation