PhosphoNET

           
Protein Info 
   
Short Name:  RPAP1
Full Name:  RNA polymerase II-associated protein 1
Alias:  DKFZp727M111; FLJ12732; KIAA1403; MGC858; RNA polymerase II associated protein 1
Type: 
Mass (Da):  152755
Number AA:  1393
UniProt ID:  Q9BWH6
International Prot ID:  IPI00402657
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003676  GO:0003677  GO:0003824 PhosphoSite+ KinaseNET
Biological Process:  GO:0006139  GO:0006350  GO:0008152 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S3_____MLSRPKPGES
Site 2S10SRPKPGESEVDLLHF
Site 3S45RGGGDANSDRPPLQD
Site 4S72LPPALVPSPPKRARP
Site 5S80PPKRARPSPGHCLPE
Site 6T114TKIIERDTSSVAVNL
Site 7S115KIIERDTSSVAVNLP
Site 8T139VFLRSRDTQGKSATS
Site 9S143SRDTQGKSATSGKRS
Site 10S146TQGKSATSGKRSIFA
Site 11S150SATSGKRSIFAQEIA
Site 12T184GPPEGAVTCETPTPR
Site 13T187EGAVTCETPTPRNQG
Site 14T189AVTCETPTPRNQGCQ
Site 15S200QGCQLPGSSHSFQGP
Site 16S201GCQLPGSSHSFQGPN
Site 17S203QLPGSSHSFQGPNLV
Site 18S264SLVAFLRSHSHTQEQ
Site 19S266VAFLRSHSHTQEQTG
Site 20T268FLRSHSHTQEQTGET
Site 21S277EQTGETASEEQRPGG
Site 22S286EQRPGGPSANVTKEE
Site 23T290GGPSANVTKEEPLMS
Site 24S297TKEEPLMSAFASEPR
Site 25S301PLMSAFASEPRKRDK
Site 26T321PALALPVTPQKEWLH
Site 27T331KEWLHMDTVELEKLH
Site 28T351PPVRRQQTQERMQAR
Site 29S360ERMQARFSLQGELLA
Site 30T374APDVDLPTHLGLHHH
Site 31Y390EEAERAGYSLQELFH
Site 32S391EAERAGYSLQELFHL
Site 33S401ELFHLTRSQVSQQRA
Site 34S404HLTRSQVSQQRALAL
Site 35S481GDEELLDSTFSWYHG
Site 36T482DEELLDSTFSWYHGA
Site 37T491SWYHGALTFPLMPSQ
Site 38S497LTFPLMPSQEDKEDE
Site 39S519AGKAKRKSPEEESRP
Site 40S524RKSPEEESRPPPDLA
Site 41S576LIRLARHSLESATRV
Site 42S579LARHSLESATRVLEC
Site 43S601VREFLPTSWSPVGAG
Site 44S603EFLPTSWSPVGAGPT
Site 45T610SPVGAGPTPSLYKVP
Site 46S641NIAARLLSSFDLRSR
Site 47T672EEAEMLSTEALRLWA
Site 48Y689ASYGQGGYLYRELYP
Site 49Y691YGQGGYLYRELYPVL
Site 50S710QVVPRELSTHPPQPL
Site 51T711VVPRELSTHPPQPLS
Site 52S718THPPQPLSMQRIASL
Site 53T743AGSTPAETISDSAEA
Site 54S745STPAETISDSAEASL
Site 55S747PAETISDSAEASLSA
Site 56S751ISDSAEASLSATPSL
Site 57T778VEPCLRQTLKLLSRP
Site 58S783RQTLKLLSRPEMWRA
Site 59Y806LLFLGAYYQAWSQQP
Site 60S814QAWSQQPSSCPEDWL
Site 61S815AWSQQPSSCPEDWLQ
Site 62S828LQDMERLSEELLLPL
Site 63S843LSQPTLGSLWDSLRH
Site 64S852WDSLRHCSLLCNPLS
Site 65S883SGGCPRLSLAGSASP
Site 66S944APHLTPFSAWALRHE
Site 67Y952AWALRHEYHLQYLAL
Site 68Y956RHEYHLQYLALALAQ
Site 69S994LSRLLPGSEYLTHEL
Site 70S1017EFLPERTSGGPEAAD
Site 71S1026GPEAADFSDQLSLGS
Site 72S1030ADFSDQLSLGSSRVP
Site 73S1033SDQLSLGSSRVPRCG
Site 74S1034DQLSLGSSRVPRCGQ
Site 75Y1059LPSIRNCYLTHCSPA
Site 76T1061SIRNCYLTHCSPARA
Site 77S1073ARASLLASQALHRGE
Site 78T1086GELQRVPTLLLPMPT
Site 79T1093TLLLPMPTEPLLPTD
Site 80Y1110FLPLIRLYHRASDTP
Site 81S1114IRLYHRASDTPSGLS
Site 82T1116LYHRASDTPSGLSPT
Site 83S1118HRASDTPSGLSPTDT
Site 84S1121SDTPSGLSPTDTMGT
Site 85T1125SGLSPTDTMGTAMRV
Site 86S1173DSELFRESPVQHLVA
Site 87T1205DCRLPGLTSFPDLYA
Site 88S1206CRLPGLTSFPDLYAN
Site 89Y1273LPVSLECYTVPPEDN
Site 90T1274PVSLECYTVPPEDNL
Site 91S1318HVNSFIFSQDPQSSD
Site 92S1323IFSQDPQSSDEVKAA
Site 93S1324FSQDPQSSDEVKAAR
Site 94S1333EVKAARRSMLQKTWL
Site 95Y1353LRQHLLHYKLPNSTL
Site 96S1358LHYKLPNSTLPEGFE
Site 97Y1367LPEGFELYSQLPPLR
Site 98S1368PEGFELYSQLPPLRQ
Site 99Y1377LPPLRQHYLQRLTST
Site 100T1382QHYLQRLTSTVLQNG
Site 101S1383HYLQRLTSTVLQNGV
Site 102T1384YLQRLTSTVLQNGVS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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