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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
REPIN1
Full Name:
Replication initiator 1
Alias:
AP4; H_DJ0584D14.12; REPI1; Replication initiation region protein (60kD); RIP60; Zfp464; Zinc finger protein 464 (RIP60); Zinc finger proten AP4; ZNF464
Type:
Mass (Da):
63570
Number AA:
UniProt ID:
Q9BWE0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005664
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
A
Q
P
R
L
L
S
G
P
S
Q
E
S
P
Site 2
S24
P
R
L
L
S
G
P
S
Q
E
S
P
Q
T
L
Site 3
S27
L
S
G
P
S
Q
E
S
P
Q
T
L
G
K
E
Site 4
T30
P
S
Q
E
S
P
Q
T
L
G
K
E
S
R
G
Site 5
T43
R
G
L
R
Q
Q
G
T
S
V
A
Q
S
G
A
Site 6
S44
G
L
R
Q
Q
G
T
S
V
A
Q
S
G
A
Q
Site 7
S48
Q
G
T
S
V
A
Q
S
G
A
Q
A
P
G
R
Site 8
T223
P
R
G
R
P
A
V
T
A
P
R
P
G
G
D
Site 9
T259
I
A
H
R
R
V
H
T
G
E
R
P
H
Q
C
Site 10
T274
P
E
C
G
K
R
F
T
N
K
P
Y
L
T
S
Site 11
Y278
K
R
F
T
N
K
P
Y
L
T
S
H
R
R
I
Site 12
T280
F
T
N
K
P
Y
L
T
S
H
R
R
I
H
T
Site 13
S281
T
N
K
P
Y
L
T
S
H
R
R
I
H
T
G
Site 14
T287
T
S
H
R
R
I
H
T
G
E
K
P
Y
P
C
Site 15
Y292
I
H
T
G
E
K
P
Y
P
C
K
E
C
G
R
Site 16
S309
R
H
K
P
N
L
L
S
H
S
K
I
H
K
R
Site 17
S329
Q
A
A
P
G
P
G
S
P
Q
L
P
A
G
P
Site 18
T344
Q
E
S
A
A
E
P
T
P
A
V
P
L
K
P
Site 19
S373
D
P
I
E
A
P
P
S
L
Y
S
C
D
D
C
Site 20
Y375
I
E
A
P
P
S
L
Y
S
C
D
D
C
G
R
Site 21
S376
E
A
P
P
S
L
Y
S
C
D
D
C
G
R
S
Site 22
S383
S
C
D
D
C
G
R
S
F
R
L
E
R
F
L
Site 23
T398
R
A
H
Q
R
Q
H
T
G
E
R
P
F
T
C
Site 24
T404
H
T
G
E
R
P
F
T
C
A
E
C
G
K
N
Site 25
T416
G
K
N
F
G
K
K
T
H
L
V
A
H
S
R
Site 26
S426
V
A
H
S
R
V
H
S
G
E
R
P
F
A
C
Site 27
S441
E
E
C
G
R
R
F
S
Q
G
S
H
L
A
A
Site 28
S444
G
R
R
F
S
Q
G
S
H
L
A
A
H
R
R
Site 29
T482
A
A
H
R
R
I
H
T
G
E
K
P
Y
V
C
Site 30
Y487
I
H
T
G
E
K
P
Y
V
C
P
D
C
G
K
Site 31
S497
P
D
C
G
K
A
F
S
Q
K
S
N
L
V
S
Site 32
S500
G
K
A
F
S
Q
K
S
N
L
V
S
H
R
R
Site 33
S504
S
Q
K
S
N
L
V
S
H
R
R
I
H
T
G
Site 34
T510
V
S
H
R
R
I
H
T
G
E
R
P
Y
A
C
Site 35
Y515
I
H
T
G
E
R
P
Y
A
C
P
D
C
D
R
Site 36
S523
A
C
P
D
C
D
R
S
F
S
Q
K
S
N
L
Site 37
S525
P
D
C
D
R
S
F
S
Q
K
S
N
L
I
T
Site 38
S528
D
R
S
F
S
Q
K
S
N
L
I
T
H
R
K
Site 39
T532
S
Q
K
S
N
L
I
T
H
R
K
S
H
I
R
Site 40
S536
N
L
I
T
H
R
K
S
H
I
R
D
G
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation