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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIFC1
Full Name:
Kinesin-like protein KIFC1
Alias:
HSET; Kinesin family member C1; Kinesin-like protein 2; Kinesin-related protein HSET; KNSL2
Type:
Motor protein; Microtubule binding protein
Mass (Da):
73748
Number AA:
673
UniProt ID:
Q9BW19
International Prot ID:
IPI00306400
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005769
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007018
GO:0000070
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
D
P
Q
R
S
P
L
L
E
V
K
G
Site 2
S26
R
P
L
I
K
A
P
S
Q
L
P
L
S
G
S
Site 3
S31
A
P
S
Q
L
P
L
S
G
S
R
L
K
R
R
Site 4
S33
S
Q
L
P
L
S
G
S
R
L
K
R
R
P
D
Site 5
T59
R
T
R
G
L
G
A
T
T
K
I
T
T
S
H
Site 6
S65
A
T
T
K
I
T
T
S
H
P
R
V
P
S
L
Site 7
S71
T
S
H
P
R
V
P
S
L
T
T
V
P
Q
T
Site 8
T73
H
P
R
V
P
S
L
T
T
V
P
Q
T
Q
G
Site 9
T74
P
R
V
P
S
L
T
T
V
P
Q
T
Q
G
Q
Site 10
T91
A
Q
K
V
S
K
K
T
G
P
R
C
S
T
A
Site 11
S96
K
K
T
G
P
R
C
S
T
A
I
A
T
G
L
Site 12
T97
K
T
G
P
R
C
S
T
A
I
A
T
G
L
K
Site 13
S117
P
A
V
P
V
Q
K
S
G
T
S
G
V
P
P
Site 14
S120
P
V
Q
K
S
G
T
S
G
V
P
P
M
A
G
Site 15
S132
M
A
G
G
K
K
P
S
K
R
P
A
W
D
L
Site 16
T157
L
K
R
C
R
E
R
T
Q
T
L
D
Q
E
N
Site 17
T159
R
C
R
E
R
T
Q
T
L
D
Q
E
N
Q
Q
Site 18
T183
Q
Q
V
K
A
L
G
T
E
R
T
T
L
E
G
Site 19
T187
A
L
G
T
E
R
T
T
L
E
G
H
L
A
K
Site 20
S221
L
E
L
E
E
R
L
S
T
Q
E
G
L
V
Q
Site 21
T222
E
L
E
E
R
L
S
T
Q
E
G
L
V
Q
E
Site 22
S246
E
E
R
R
G
L
M
S
Q
L
E
E
K
E
R
Site 23
T257
E
K
E
R
R
L
Q
T
S
E
A
A
L
S
S
Site 24
S258
K
E
R
R
L
Q
T
S
E
A
A
L
S
S
S
Site 25
S263
Q
T
S
E
A
A
L
S
S
S
Q
A
E
V
A
Site 26
S265
S
E
A
A
L
S
S
S
Q
A
E
V
A
S
L
Site 27
S271
S
S
Q
A
E
V
A
S
L
R
Q
E
T
V
A
Site 28
T284
V
A
Q
A
A
L
L
T
E
R
E
E
R
L
H
Site 29
S336
P
G
L
L
L
F
P
S
G
P
G
G
P
S
D
Site 30
S342
P
S
G
P
G
G
P
S
D
P
P
T
R
L
S
Site 31
T346
G
G
P
S
D
P
P
T
R
L
S
L
S
R
S
Site 32
S349
S
D
P
P
T
R
L
S
L
S
R
S
D
E
R
Site 33
S351
P
P
T
R
L
S
L
S
R
S
D
E
R
R
G
Site 34
S353
T
R
L
S
L
S
R
S
D
E
R
R
G
T
L
Site 35
T359
R
S
D
E
R
R
G
T
L
S
G
A
P
A
P
Site 36
S361
D
E
R
R
G
T
L
S
G
A
P
A
P
P
T
Site 37
T368
S
G
A
P
A
P
P
T
R
H
D
F
S
F
D
Site 38
S373
P
P
T
R
H
D
F
S
F
D
R
V
F
P
P
Site 39
S382
D
R
V
F
P
P
G
S
G
Q
D
E
V
F
E
Site 40
S414
F
A
Y
G
Q
T
G
S
G
K
T
F
T
M
E
Site 41
T417
G
Q
T
G
S
G
K
T
F
T
M
E
G
G
P
Site 42
T419
T
G
S
G
K
T
F
T
M
E
G
G
P
G
G
Site 43
S443
R
A
L
R
H
L
F
S
V
A
Q
E
L
S
G
Site 44
S449
F
S
V
A
Q
E
L
S
G
Q
G
W
T
Y
S
Site 45
S456
S
G
Q
G
W
T
Y
S
F
V
A
S
Y
V
E
Site 46
Y461
T
Y
S
F
V
A
S
Y
V
E
I
Y
N
E
T
Site 47
T468
Y
V
E
I
Y
N
E
T
V
R
D
L
L
A
T
Site 48
T475
T
V
R
D
L
L
A
T
G
T
R
K
G
Q
G
Site 49
S494
I
R
R
A
G
P
G
S
E
E
L
T
V
T
N
Site 50
T498
G
P
G
S
E
E
L
T
V
T
N
A
R
Y
V
Site 51
T500
G
S
E
E
L
T
V
T
N
A
R
Y
V
P
V
Site 52
Y504
L
T
V
T
N
A
R
Y
V
P
V
S
C
E
K
Site 53
S508
N
A
R
Y
V
P
V
S
C
E
K
E
V
D
A
Site 54
T529
Q
N
R
A
V
A
R
T
A
Q
N
E
R
S
S
Site 55
S535
R
T
A
Q
N
E
R
S
S
R
S
H
S
V
F
Site 56
S536
T
A
Q
N
E
R
S
S
R
S
H
S
V
F
Q
Site 57
S538
Q
N
E
R
S
S
R
S
H
S
V
F
Q
L
Q
Site 58
S540
E
R
S
S
R
S
H
S
V
F
Q
L
Q
I
S
Site 59
S547
S
V
F
Q
L
Q
I
S
G
E
H
S
S
R
G
Site 60
S551
L
Q
I
S
G
E
H
S
S
R
G
L
Q
C
G
Site 61
T589
E
R
E
R
L
R
E
T
Q
A
I
N
S
S
L
Site 62
S611
M
A
L
S
N
K
E
S
H
V
P
Y
R
N
S
Site 63
Y615
N
K
E
S
H
V
P
Y
R
N
S
K
L
T
Y
Site 64
S618
S
H
V
P
Y
R
N
S
K
L
T
Y
L
L
Q
Site 65
T621
P
Y
R
N
S
K
L
T
Y
L
L
Q
N
S
L
Site 66
Y622
Y
R
N
S
K
L
T
Y
L
L
Q
N
S
L
G
Site 67
S648
S
P
L
E
E
N
V
S
E
S
L
N
S
L
R
Site 68
S650
L
E
E
N
V
S
E
S
L
N
S
L
R
F
A
Site 69
S653
N
V
S
E
S
L
N
S
L
R
F
A
S
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation