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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNL3
Full Name:
Guanine nucleotide-binding protein-like 3
Alias:
C77032; E2IG3; E2-induced gene 3 protein; E2-induced gene 3-protein; Guanine nucleotide binding protein-like 3 (nucleolar); MGC800; NNP47; Novel nucleolar protein 47; NS; Nucleolar GTP-binding protein 3; Nucleostemin
Type:
Cell cycle regulation; G protein
Mass (Da):
61975
Number AA:
549
UniProt ID:
Q9BVP2
International Prot ID:
IPI00306380
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0042127
GO:0050789
GO:0050794
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
R
P
K
L
K
K
A
S
K
R
M
T
C
H
K
Site 2
T14
K
K
A
S
K
R
M
T
C
H
K
R
Y
K
I
Site 3
S53
K
D
P
G
V
P
N
S
A
P
F
K
E
A
L
Site 4
S101
T
N
P
D
I
K
P
S
N
V
E
P
M
E
K
Site 5
T115
K
E
F
G
L
C
K
T
E
N
K
A
K
S
G
Site 6
S121
K
T
E
N
K
A
K
S
G
K
Q
N
S
K
K
Site 7
Y130
K
Q
N
S
K
K
L
Y
C
Q
E
L
K
K
V
Site 8
Y194
N
L
E
S
W
L
N
Y
L
K
K
E
L
P
T
Site 9
S207
P
T
V
V
F
R
A
S
T
K
P
K
D
K
G
Site 10
T208
T
V
V
F
R
A
S
T
K
P
K
D
K
G
K
Site 11
T217
P
K
D
K
G
K
I
T
K
R
V
K
A
K
K
Site 12
S252
G
G
F
Q
E
T
C
S
K
A
I
R
V
G
V
Site 13
S268
G
F
P
N
V
G
K
S
S
I
I
N
S
L
K
Site 14
S269
F
P
N
V
G
K
S
S
I
I
N
S
L
K
Q
Site 15
S273
G
K
S
S
I
I
N
S
L
K
Q
E
Q
M
C
Site 16
S312
D
S
P
S
F
I
V
S
P
L
N
S
S
S
A
Site 17
S318
V
S
P
L
N
S
S
S
A
L
A
L
R
S
P
Site 18
S342
E
A
A
S
A
I
L
S
Q
A
D
A
R
Q
V
Site 19
Y353
A
R
Q
V
V
L
K
Y
T
V
P
G
Y
R
N
Site 20
T354
R
Q
V
V
L
K
Y
T
V
P
G
Y
R
N
S
Site 21
Y358
L
K
Y
T
V
P
G
Y
R
N
S
L
E
F
F
Site 22
T366
R
N
S
L
E
F
F
T
V
L
A
Q
R
R
G
Site 23
Y401
W
T
G
A
S
L
A
Y
Y
C
H
P
P
T
S
Site 24
Y402
T
G
A
S
L
A
Y
Y
C
H
P
P
T
S
W
Site 25
Y414
T
S
W
T
P
P
P
Y
F
N
E
S
I
V
V
Site 26
S439
L
E
K
N
N
A
Q
S
I
R
A
I
K
G
P
Site 27
S451
K
G
P
H
L
A
N
S
I
L
F
Q
S
S
G
Site 28
T460
L
F
Q
S
S
G
L
T
N
G
I
I
E
E
K
Site 29
S490
E
R
E
D
D
K
D
S
D
Q
E
T
V
D
E
Site 30
T494
D
K
D
S
D
Q
E
T
V
D
E
E
V
D
E
Site 31
S503
D
E
E
V
D
E
N
S
S
G
M
F
A
A
E
Site 32
T520
G
E
A
L
S
E
E
T
T
A
G
E
Q
S
T
Site 33
T521
E
A
L
S
E
E
T
T
A
G
E
Q
S
T
R
Site 34
S526
E
T
T
A
G
E
Q
S
T
R
S
F
I
L
D
Site 35
S529
A
G
E
Q
S
T
R
S
F
I
L
D
K
I
I
Site 36
Y542
I
I
E
E
D
D
A
Y
D
F
S
T
D
Y
V
Site 37
S545
E
D
D
A
Y
D
F
S
T
D
Y
V
_
_
_
Site 38
Y548
A
Y
D
F
S
T
D
Y
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation