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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPON2
Full Name:
Spondin-2
Alias:
Differentially expressed in cancerous and non-cancerous lung cells 1;Mindin
Type:
Mass (Da):
35830
Number AA:
331
UniProt ID:
Q9BUD6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
E
N
P
S
P
A
A
A
L
G
K
Site 2
S33
G
Q
P
L
G
G
E
S
I
C
S
A
R
A
P
Site 3
S36
L
G
G
E
S
I
C
S
A
R
A
P
A
K
Y
Site 4
Y43
S
A
R
A
P
A
K
Y
S
I
T
F
T
G
K
Site 5
S44
A
R
A
P
A
K
Y
S
I
T
F
T
G
K
W
Site 6
T46
A
P
A
K
Y
S
I
T
F
T
G
K
W
S
Q
Site 7
T48
A
K
Y
S
I
T
F
T
G
K
W
S
Q
T
A
Site 8
Y60
Q
T
A
F
P
K
Q
Y
P
L
F
R
P
P
A
Site 9
S71
R
P
P
A
Q
W
S
S
L
L
G
A
A
H
S
Site 10
S78
S
L
L
G
A
A
H
S
S
D
Y
S
M
W
R
Site 11
Y81
G
A
A
H
S
S
D
Y
S
M
W
R
K
N
Q
Site 12
Y89
S
M
W
R
K
N
Q
Y
V
S
N
G
L
R
D
Site 13
S125
Q
S
V
H
E
V
F
S
A
P
A
V
P
S
G
Site 14
S131
F
S
A
P
A
V
P
S
G
T
G
Q
T
S
A
Site 15
S147
L
E
V
Q
R
R
H
S
L
V
S
F
V
V
R
Site 16
S167
D
W
F
V
G
V
D
S
L
D
L
C
D
G
D
Site 17
Y185
E
Q
A
A
L
D
L
Y
P
Y
D
A
G
T
D
Site 18
Y187
A
A
L
D
L
Y
P
Y
D
A
G
T
D
S
G
Site 19
T191
L
Y
P
Y
D
A
G
T
D
S
G
F
T
F
S
Site 20
S193
P
Y
D
A
G
T
D
S
G
F
T
F
S
S
P
Site 21
T196
A
G
T
D
S
G
F
T
F
S
S
P
N
F
A
Site 22
S198
T
D
S
G
F
T
F
S
S
P
N
F
A
T
I
Site 23
S199
D
S
G
F
T
F
S
S
P
N
F
A
T
I
P
Site 24
T209
F
A
T
I
P
Q
D
T
V
T
E
I
T
S
S
Site 25
T211
T
I
P
Q
D
T
V
T
E
I
T
S
S
S
P
Site 26
S215
D
T
V
T
E
I
T
S
S
S
P
S
H
P
A
Site 27
S216
T
V
T
E
I
T
S
S
S
P
S
H
P
A
N
Site 28
S217
V
T
E
I
T
S
S
S
P
S
H
P
A
N
S
Site 29
S219
E
I
T
S
S
S
P
S
H
P
A
N
S
F
Y
Site 30
S224
S
P
S
H
P
A
N
S
F
Y
Y
P
R
L
K
Site 31
Y226
S
H
P
A
N
S
F
Y
Y
P
R
L
K
A
L
Site 32
Y227
H
P
A
N
S
F
Y
Y
P
R
L
K
A
L
P
Site 33
S247
T
L
V
R
L
R
Q
S
P
R
A
F
I
P
P
Site 34
S268
R
D
N
E
I
V
D
S
A
S
V
P
E
T
P
Site 35
S270
N
E
I
V
D
S
A
S
V
P
E
T
P
L
D
Site 36
T274
D
S
A
S
V
P
E
T
P
L
D
C
E
V
S
Site 37
T298
G
H
C
G
R
L
G
T
K
S
R
T
R
Y
V
Site 38
S300
C
G
R
L
G
T
K
S
R
T
R
Y
V
R
V
Site 39
Y304
G
T
K
S
R
T
R
Y
V
R
V
Q
P
A
N
Site 40
S314
V
Q
P
A
N
N
G
S
P
C
P
E
L
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation