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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM112B
Full Name:
Lipase maturation factor 2
Alias:
TMEM153; Transmembrane protein 112B; Transmembrane protein 153
Type:
Mass (Da):
79700
Number AA:
UniProt ID:
Q9BU23
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T45
G
I
L
P
A
R
R
T
L
R
P
Q
G
K
G
Site 2
T60
R
W
Q
Q
L
W
E
T
P
T
L
L
W
E
A
Site 3
S147
V
A
P
L
R
P
A
S
H
R
K
E
A
P
Q
Site 4
Y202
W
G
L
T
A
L
T
Y
H
Y
E
T
Q
C
L
Site 5
T303
G
H
G
S
R
K
K
T
A
T
S
W
P
K
A
Site 6
T305
G
S
R
K
K
T
A
T
S
W
P
K
A
L
L
Site 7
T351
R
T
I
H
S
R
T
T
F
T
F
H
Q
F
S
Site 8
T363
Q
F
S
Q
W
L
K
T
L
T
L
P
T
V
W
Site 9
Y423
I
S
L
V
P
Y
S
Y
V
E
P
G
T
H
G
Site 10
T428
Y
S
Y
V
E
P
G
T
H
G
R
L
W
T
G
Site 11
T434
G
T
H
G
R
L
W
T
G
A
H
R
L
F
G
Site 12
S451
E
H
L
Q
L
A
N
S
Y
G
L
F
R
R
M
Site 13
T459
Y
G
L
F
R
R
M
T
G
L
G
G
R
P
E
Site 14
Y485
W
T
E
I
E
F
M
Y
K
P
G
N
L
S
R
Site 15
S491
M
Y
K
P
G
N
L
S
R
P
P
P
V
V
V
Site 16
T517
F
A
A
L
G
P
H
T
H
S
P
W
F
T
S
Site 17
Y547
V
Q
S
Q
V
A
R
Y
P
F
H
K
Q
P
P
Site 18
T555
P
F
H
K
Q
P
P
T
Y
V
R
A
Q
R
Y
Site 19
Y556
F
H
K
Q
P
P
T
Y
V
R
A
Q
R
Y
K
Site 20
Y562
T
Y
V
R
A
Q
R
Y
K
Y
W
F
S
Q
P
Site 21
Y564
V
R
A
Q
R
Y
K
Y
W
F
S
Q
P
G
E
Site 22
S587
W
V
E
E
F
F
P
S
V
S
L
G
D
P
T
Site 23
S589
E
E
F
F
P
S
V
S
L
G
D
P
T
L
E
Site 24
T594
S
V
S
L
G
D
P
T
L
E
T
L
L
R
Q
Site 25
S608
Q
F
G
L
Q
E
K
S
P
P
R
T
R
S
A
Site 26
T612
Q
E
K
S
P
P
R
T
R
S
A
N
S
T
L
Site 27
S614
K
S
P
P
R
T
R
S
A
N
S
T
L
A
Q
Site 28
S617
P
R
T
R
S
A
N
S
T
L
A
Q
A
L
H
Site 29
T618
R
T
R
S
A
N
S
T
L
A
Q
A
L
H
W
Site 30
S628
Q
A
L
H
W
T
R
S
Q
L
S
P
L
E
A
Site 31
S631
H
W
T
R
S
Q
L
S
P
L
E
A
P
A
L
Site 32
S670
S
S
P
L
A
P
V
S
G
E
K
R
R
P
A
Site 33
S678
G
E
K
R
R
P
A
S
Q
K
D
S
G
A
A
Site 34
S682
R
P
A
S
Q
K
D
S
G
A
A
S
E
Q
A
Site 35
S686
Q
K
D
S
G
A
A
S
E
Q
A
T
A
A
P
Site 36
T690
G
A
A
S
E
Q
A
T
A
A
P
N
P
C
S
Site 37
S697
T
A
A
P
N
P
C
S
S
S
S
R
T
T
R
Site 38
S698
A
A
P
N
P
C
S
S
S
S
R
T
T
R
R
Site 39
S699
A
P
N
P
C
S
S
S
S
R
T
T
R
R
K
Site 40
S700
P
N
P
C
S
S
S
S
R
T
T
R
R
K
K
Site 41
T702
P
C
S
S
S
S
R
T
T
R
R
K
K
_
_
Site 42
T703
C
S
S
S
S
R
T
T
R
R
K
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation