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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NDFIP1
Full Name:
NEDD4 family-interacting protein 1
Alias:
Breast cancer-associated protein SGA-1M; MAPK-activating protein PM13; NEDD4 WW domain-binding 5; NEDD4 WW domain-binding protein 5; NFIP1; NF-kappa-B-activating 164
Type:
Adaptor/scaffold
Mass (Da):
24899
Number AA:
221
UniProt ID:
Q9BT67
International Prot ID:
IPI00012235
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0005794
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0009966
GO:0009967
GO:0043122
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
E
P
A
C
G
S
R
Y
Q
Q
L
Q
N
E
E
Site 2
Y42
A
G
D
A
P
P
P
Y
S
S
I
S
A
E
S
Site 3
S43
G
D
A
P
P
P
Y
S
S
I
S
A
E
S
A
Site 4
S44
D
A
P
P
P
Y
S
S
I
S
A
E
S
A
A
Site 5
S46
P
P
P
Y
S
S
I
S
A
E
S
A
A
Y
F
Site 6
Y52
I
S
A
E
S
A
A
Y
F
D
Y
K
D
E
S
Site 7
Y55
E
S
A
A
Y
F
D
Y
K
D
E
S
G
F
P
Site 8
S59
Y
F
D
Y
K
D
E
S
G
F
P
K
P
P
S
Site 9
S66
S
G
F
P
K
P
P
S
Y
N
V
A
T
T
L
Site 10
Y67
G
F
P
K
P
P
S
Y
N
V
A
T
T
L
P
Site 11
T71
P
P
S
Y
N
V
A
T
T
L
P
S
Y
D
E
Site 12
Y76
V
A
T
T
L
P
S
Y
D
E
A
E
R
T
K
Site 13
T82
S
Y
D
E
A
E
R
T
K
A
E
A
T
I
P
Site 14
Y147
T
T
S
A
A
G
R
Y
G
A
I
S
G
F
G
Site 15
S151
A
G
R
Y
G
A
I
S
G
F
G
L
S
L
I
Site 16
S156
A
I
S
G
F
G
L
S
L
I
K
W
I
L
I
Site 17
Y173
F
S
T
Y
F
P
G
Y
F
D
G
Q
Y
W
L
Site 18
Y199
F
L
R
G
F
I
N
Y
A
K
V
R
K
M
P
Site 19
T208
K
V
R
K
M
P
E
T
F
S
N
L
P
R
T
Site 20
S210
R
K
M
P
E
T
F
S
N
L
P
R
T
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation