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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RTKN
Full Name:
Rhotekin
Alias:
B5
Type:
G protein regulator, misc.
Mass (Da):
62670
Number AA:
UniProt ID:
Q9BST9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0017049
GO:0005095
PhosphoSite+
KinaseNET
Biological Process:
GO:0007266
GO:0006915
GO:0045767
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
R
N
H
R
S
R
V
T
V
A
R
G
S
A
L
Site 2
S16
R
V
T
V
A
R
G
S
A
L
E
M
E
F
K
Site 3
S30
K
R
G
R
F
R
L
S
L
F
S
D
L
P
E
Site 4
S33
R
F
R
L
S
L
F
S
D
L
P
E
D
T
E
Site 5
S63
C
K
L
L
A
A
C
S
Q
R
E
Q
A
L
E
Site 6
S74
Q
A
L
E
A
T
K
S
L
L
V
C
N
S
R
Site 7
S84
V
C
N
S
R
I
L
S
Y
M
G
E
L
Q
R
Site 8
T101
E
A
Q
V
L
G
K
T
S
R
R
P
S
D
S
Site 9
S102
A
Q
V
L
G
K
T
S
R
R
P
S
D
S
G
Site 10
S106
G
K
T
S
R
R
P
S
D
S
G
P
P
A
E
Site 11
S108
T
S
R
R
P
S
D
S
G
P
P
A
E
R
S
Site 12
S115
S
G
P
P
A
E
R
S
P
C
R
G
R
V
C
Site 13
Y137
L
M
W
K
D
T
E
Y
F
K
N
K
G
D
L
Site 14
T162
L
G
E
H
I
Q
D
T
E
M
I
L
V
D
R
Site 15
T172
I
L
V
D
R
T
L
T
D
I
S
F
Q
S
N
Site 16
S175
D
R
T
L
T
D
I
S
F
Q
S
N
V
L
F
Site 17
Y196
F
E
L
R
L
E
L
Y
G
A
C
V
E
E
E
Site 18
T207
V
E
E
E
G
A
L
T
G
G
P
K
R
L
A
Site 19
T215
G
G
P
K
R
L
A
T
K
L
S
S
S
L
G
Site 20
S218
K
R
L
A
T
K
L
S
S
S
L
G
R
S
S
Site 21
S219
R
L
A
T
K
L
S
S
S
L
G
R
S
S
G
Site 22
S220
L
A
T
K
L
S
S
S
L
G
R
S
S
G
R
Site 23
S224
L
S
S
S
L
G
R
S
S
G
R
R
V
R
A
Site 24
S225
S
S
S
L
G
R
S
S
G
R
R
V
R
A
S
Site 25
S232
S
G
R
R
V
R
A
S
L
D
S
A
G
G
S
Site 26
S235
R
V
R
A
S
L
D
S
A
G
G
S
G
S
S
Site 27
S239
S
L
D
S
A
G
G
S
G
S
S
P
I
L
L
Site 28
S241
D
S
A
G
G
S
G
S
S
P
I
L
L
P
T
Site 29
S242
S
A
G
G
S
G
S
S
P
I
L
L
P
T
P
Site 30
Y256
P
V
V
G
G
P
R
Y
H
L
L
A
H
T
T
Site 31
T279
G
F
R
T
H
D
L
T
L
A
S
H
E
E
N
Site 32
S282
T
H
D
L
T
L
A
S
H
E
E
N
P
A
W
Site 33
T315
T
Q
P
T
A
S
G
T
L
R
V
Q
Q
A
G
Site 34
Y342
K
G
T
N
L
F
C
Y
R
Q
P
E
D
A
D
Site 35
T350
R
Q
P
E
D
A
D
T
G
E
E
P
L
L
T
Site 36
T357
T
G
E
E
P
L
L
T
I
A
V
N
K
E
T
Site 37
T380
Q
A
L
G
R
P
F
T
L
S
I
S
N
Q
Y
Site 38
S382
L
G
R
P
F
T
L
S
I
S
N
Q
Y
G
D
Site 39
S384
R
P
F
T
L
S
I
S
N
Q
Y
G
D
D
E
Site 40
T395
G
D
D
E
V
T
H
T
L
Q
T
E
S
R
E
Site 41
S406
E
S
R
E
A
L
Q
S
W
M
E
A
L
W
Q
Site 42
T433
D
E
I
M
K
I
E
T
P
A
P
R
K
P
P
Site 43
S448
Q
A
L
A
K
Q
G
S
L
Y
H
E
M
A
I
Site 44
Y450
L
A
K
Q
G
S
L
Y
H
E
M
A
I
E
P
Site 45
T469
A
A
V
T
D
I
L
T
Q
R
E
G
A
R
L
Site 46
T478
R
E
G
A
R
L
E
T
P
P
P
W
L
A
M
Site 47
T487
P
P
W
L
A
M
F
T
D
Q
P
A
L
P
N
Site 48
S500
P
N
P
C
S
P
A
S
V
A
P
A
P
D
W
Site 49
T508
V
A
P
A
P
D
W
T
H
P
L
P
W
G
R
Site 50
T518
L
P
W
G
R
P
R
T
F
S
L
D
A
V
P
Site 51
S520
W
G
R
P
R
T
F
S
L
D
A
V
P
P
D
Site 52
S529
D
A
V
P
P
D
H
S
P
R
A
R
S
V
A
Site 53
S534
D
H
S
P
R
A
R
S
V
A
P
L
P
P
Q
Site 54
S543
A
P
L
P
P
Q
R
S
P
R
T
R
G
L
C
Site 55
T557
C
S
K
G
Q
P
R
T
W
L
Q
S
P
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation