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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FEM1A
Full Name:
Protein fem-1 homolog A
Alias:
FEM1-alpha;Prostaglandin E receptor 4-associated protein
Type:
Mass (Da):
73639
Number AA:
669
UniProt ID:
Q9BSK4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
D
L
R
T
A
V
Y
N
A
A
R
D
G
K
Site 2
S24
Q
L
L
Q
K
L
L
S
G
R
S
R
E
E
L
Site 3
T35
R
E
E
L
D
E
L
T
G
E
V
A
G
G
G
Site 4
S73
A
S
V
E
A
G
G
S
V
H
F
D
G
E
T
Site 5
T80
S
V
H
F
D
G
E
T
I
E
G
A
P
P
L
Site 6
S101
G
H
L
D
V
V
R
S
L
L
R
R
G
A
S
Site 7
S108
S
L
L
R
R
G
A
S
V
N
R
T
T
R
T
Site 8
T112
R
G
A
S
V
N
R
T
T
R
T
N
S
T
P
Site 9
T113
G
A
S
V
N
R
T
T
R
T
N
S
T
P
L
Site 10
T115
S
V
N
R
T
T
R
T
N
S
T
P
L
R
A
Site 11
S117
N
R
T
T
R
T
N
S
T
P
L
R
A
A
C
Site 12
T118
R
T
T
R
T
N
S
T
P
L
R
A
A
C
F
Site 13
Y134
G
H
L
E
V
V
R
Y
L
V
G
E
H
Q
A
Site 14
Y168
G
H
R
E
I
A
R
Y
L
L
E
Q
G
A
Q
Site 15
S180
G
A
Q
V
N
R
R
S
A
K
G
N
T
A
L
Site 16
Y214
A
R
M
E
R
D
G
Y
G
M
T
P
L
L
A
Site 17
T217
E
R
D
G
Y
G
M
T
P
L
L
A
A
S
V
Site 18
Y233
G
H
T
N
I
V
E
Y
L
I
Q
E
Q
P
G
Site 19
S259
G
L
P
Q
E
D
P
S
T
S
Q
G
C
A
Q
Site 20
T260
L
P
Q
E
D
P
S
T
S
Q
G
C
A
Q
P
Site 21
S261
P
Q
E
D
P
S
T
S
Q
G
C
A
Q
P
Q
Site 22
S274
P
Q
G
A
P
C
C
S
S
S
P
E
E
P
L
Site 23
S276
G
A
P
C
C
S
S
S
P
E
E
P
L
N
G
Site 24
Y286
E
P
L
N
G
E
S
Y
E
S
C
C
P
T
S
Site 25
S288
L
N
G
E
S
Y
E
S
C
C
P
T
S
R
E
Site 26
T292
S
Y
E
S
C
C
P
T
S
R
E
A
A
V
E
Site 27
Y308
L
E
L
L
G
A
T
Y
V
D
K
K
R
D
L
Site 28
Y335
L
R
H
Q
G
G
E
Y
L
P
K
P
E
P
P
Site 29
Y350
Q
L
V
L
A
Y
D
Y
S
R
E
V
N
T
T
Site 30
S351
L
V
L
A
Y
D
Y
S
R
E
V
N
T
T
E
Site 31
T357
Y
S
R
E
V
N
T
T
E
E
L
E
A
L
I
Site 32
T365
E
E
L
E
A
L
I
T
D
P
D
E
M
R
M
Site 33
S385
R
E
R
I
L
G
P
S
H
P
D
T
S
Y
Y
Site 34
T389
L
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
Site 35
S390
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
Site 36
Y391
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
A
Site 37
Y392
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
A
V
Site 38
S403
R
G
A
V
Y
A
D
S
G
N
F
E
R
C
I
Site 39
Y415
R
C
I
R
L
W
K
Y
A
L
D
M
Q
Q
S
Site 40
S422
Y
A
L
D
M
Q
Q
S
N
L
E
P
L
S
P
Site 41
S428
Q
S
N
L
E
P
L
S
P
M
T
A
S
S
F
Site 42
S454
Q
D
R
A
A
K
G
S
L
G
T
Q
I
G
F
Site 43
S488
L
P
R
E
P
G
D
S
A
Q
F
T
K
A
L
Site 44
T511
L
L
E
K
V
E
C
T
P
S
Q
E
H
L
K
Site 45
S513
E
K
V
E
C
T
P
S
Q
E
H
L
K
H
Q
Site 46
T521
Q
E
H
L
K
H
Q
T
V
Y
R
L
L
K
C
Site 47
T537
P
R
G
K
N
G
F
T
P
L
H
M
A
V
D
Site 48
T547
H
M
A
V
D
K
D
T
T
N
V
G
R
Y
P
Site 49
T548
M
A
V
D
K
D
T
T
N
V
G
R
Y
P
V
Site 50
Y553
D
T
T
N
V
G
R
Y
P
V
G
R
F
P
S
Site 51
S576
D
C
G
A
D
P
D
S
R
D
F
D
N
N
T
Site 52
T583
S
R
D
F
D
N
N
T
P
L
H
I
A
A
Q
Site 53
T610
A
G
A
H
M
D
A
T
N
A
F
K
K
T
A
Site 54
T630
E
K
L
L
A
R
G
T
M
Q
P
F
N
Y
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation