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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM56
Full Name:
Tripartite motif-containing protein 56
Alias:
RING finger protein 109; RNF109; TRI56; Tripartite motif-containing 56
Type:
Unknown function
Mass (Da):
81488
Number AA:
755
UniProt ID:
Q9BRZ2
International Prot ID:
IPI00514832
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
V
S
H
G
S
S
P
S
L
L
E
A
Site 2
S7
_
M
V
S
H
G
S
S
P
S
L
L
E
A
L
Site 3
S9
V
S
H
G
S
S
P
S
L
L
E
A
L
S
S
Site 4
T33
E
Q
L
R
A
P
K
T
L
P
C
L
H
T
Y
Site 5
T62
R
C
P
E
C
R
E
T
V
P
V
P
P
E
G
Site 6
T117
T
S
T
G
G
P
A
T
A
R
C
L
D
C
A
Site 7
T143
R
C
T
R
Q
T
H
T
H
R
V
V
D
L
V
Site 8
Y157
V
G
Y
R
A
G
W
Y
D
E
E
A
R
E
R
Site 9
T253
E
Q
A
A
R
V
G
T
Q
V
E
E
A
A
E
Site 10
S314
A
F
A
R
R
V
L
S
L
G
R
E
A
E
I
Site 11
S369
N
C
H
L
L
R
L
S
F
E
E
Q
Q
P
Q
Site 12
S392
G
T
Q
G
G
E
E
S
Q
S
R
R
E
D
E
Site 13
S394
Q
G
G
E
E
S
Q
S
R
R
E
D
E
P
K
Site 14
T402
R
R
E
D
E
P
K
T
E
R
Q
G
G
V
Q
Site 15
T418
Q
A
G
D
G
A
Q
T
P
K
E
E
K
A
Q
Site 16
T426
P
K
E
E
K
A
Q
T
T
R
E
E
G
A
Q
Site 17
T434
T
R
E
E
G
A
Q
T
L
E
E
D
R
A
Q
Site 18
T442
L
E
E
D
R
A
Q
T
P
H
E
D
G
G
P
Site 19
S469
K
F
K
G
R
L
K
S
I
S
R
E
P
S
P
Site 20
S471
K
G
R
L
K
S
I
S
R
E
P
S
P
A
L
Site 21
S475
K
S
I
S
R
E
P
S
P
A
L
G
P
N
L
Site 22
S507
R
M
P
G
D
K
R
S
P
R
I
T
G
L
C
Site 23
T511
D
K
R
S
P
R
I
T
G
L
C
P
F
G
P
Site 24
S535
N
R
A
L
K
R
F
S
L
N
G
D
Y
K
G
Site 25
Y540
R
F
S
L
N
G
D
Y
K
G
T
V
P
V
P
Site 26
T543
L
N
G
D
Y
K
G
T
V
P
V
P
E
G
C
Site 27
Y571
F
S
A
S
A
R
L
Y
L
I
N
P
N
G
E
Site 28
S586
V
Q
W
R
R
A
L
S
L
S
Q
A
S
H
A
Site 29
S588
W
R
R
A
L
S
L
S
Q
A
S
H
A
V
A
Site 30
S619
E
V
Y
N
M
E
G
S
L
A
T
R
F
I
P
Site 31
Y671
L
G
Q
V
V
G
E
Y
K
G
P
G
L
H
G
Site 32
S683
L
H
G
C
Q
P
G
S
V
S
V
D
K
K
G
Site 33
S685
G
C
Q
P
G
S
V
S
V
D
K
K
G
Y
I
Site 34
T695
K
K
G
Y
I
F
L
T
L
R
E
V
N
K
V
Site 35
S710
V
I
L
D
P
K
G
S
L
L
G
D
F
L
T
Site 36
Y719
L
G
D
F
L
T
A
Y
H
G
L
E
K
P
R
Site 37
T728
G
L
E
K
P
R
V
T
T
M
V
D
G
R
Y
Site 38
T729
L
E
K
P
R
V
T
T
M
V
D
G
R
Y
L
Site 39
S739
D
G
R
Y
L
V
V
S
L
S
N
G
T
I
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation