KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PELO
Full Name:
Protein pelota homolog
Alias:
pelota; pelota homolog
Type:
EC 3.1.-.-; Hydrolase
Mass (Da):
43377
Number AA:
385
UniProt ID:
Q9BRX2
International Prot ID:
IPI00106698
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
GO:0008152
GO:0009058
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
K
D
N
A
G
Q
V
T
L
V
P
E
E
P
E
Site 2
Y30
P
E
D
M
W
H
T
Y
N
L
V
Q
V
G
D
Site 3
S38
N
L
V
Q
V
G
D
S
L
R
A
S
T
I
R
Site 4
S42
V
G
D
S
L
R
A
S
T
I
R
K
V
Q
T
Site 5
T43
G
D
S
L
R
A
S
T
I
R
K
V
Q
T
E
Site 6
T49
S
T
I
R
K
V
Q
T
E
S
S
T
G
S
V
Site 7
S51
I
R
K
V
Q
T
E
S
S
T
G
S
V
G
S
Site 8
S52
R
K
V
Q
T
E
S
S
T
G
S
V
G
S
N
Site 9
T53
K
V
Q
T
E
S
S
T
G
S
V
G
S
N
R
Site 10
S55
Q
T
E
S
S
T
G
S
V
G
S
N
R
V
R
Site 11
S58
S
S
T
G
S
V
G
S
N
R
V
R
T
T
L
Site 12
T64
G
S
N
R
V
R
T
T
L
T
L
C
V
E
A
Site 13
Y93
T
N
I
Q
E
N
E
Y
V
K
M
G
A
Y
H
Site 14
Y99
E
Y
V
K
M
G
A
Y
H
T
I
E
L
E
P
Site 15
T101
V
K
M
G
A
Y
H
T
I
E
L
E
P
N
R
Site 16
T111
L
E
P
N
R
Q
F
T
L
A
K
K
Q
W
D
Site 17
S119
L
A
K
K
Q
W
D
S
V
V
L
E
R
I
E
Site 18
T159
V
T
P
S
M
T
L
T
R
A
K
V
E
V
N
Site 19
S176
R
K
R
K
G
N
C
S
Q
H
D
R
A
L
E
Site 20
Y186
D
R
A
L
E
R
F
Y
E
Q
V
V
Q
A
I
Site 21
Y220
V
R
E
Q
F
C
D
Y
M
F
Q
Q
A
V
K
Site 22
T228
M
F
Q
Q
A
V
K
T
D
N
K
L
L
L
E
Site 23
S238
K
L
L
L
E
N
R
S
K
F
L
Q
V
H
A
Site 24
S246
K
F
L
Q
V
H
A
S
S
G
H
K
Y
S
L
Site 25
Y251
H
A
S
S
G
H
K
Y
S
L
K
E
A
L
C
Site 26
S252
A
S
S
G
H
K
Y
S
L
K
E
A
L
C
D
Site 27
T261
K
E
A
L
C
D
P
T
V
A
S
R
L
S
D
Site 28
S264
L
C
D
P
T
V
A
S
R
L
S
D
T
K
A
Site 29
S267
P
T
V
A
S
R
L
S
D
T
K
A
A
G
E
Site 30
Y282
V
K
A
L
D
D
F
Y
K
M
L
Q
H
E
P
Site 31
Y294
H
E
P
D
R
A
F
Y
G
L
K
Q
V
E
K
Site 32
T325
F
R
H
Q
D
V
A
T
R
S
R
Y
V
R
L
Site 33
S327
H
Q
D
V
A
T
R
S
R
Y
V
R
L
V
D
Site 34
Y329
D
V
A
T
R
S
R
Y
V
R
L
V
D
S
V
Site 35
S335
R
Y
V
R
L
V
D
S
V
K
E
N
A
G
T
Site 36
T342
S
V
K
E
N
A
G
T
V
R
I
F
S
S
L
Site 37
S348
G
T
V
R
I
F
S
S
L
H
V
S
G
E
Q
Site 38
S374
R
F
P
V
P
E
L
S
D
Q
E
G
D
S
S
Site 39
S380
L
S
D
Q
E
G
D
S
S
S
E
E
D
_
_
Site 40
S381
S
D
Q
E
G
D
S
S
S
E
E
D
_
_
_
Site 41
S382
D
Q
E
G
D
S
S
S
E
E
D
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation