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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARHGAP9
Full Name:
Rho GTPase-activating protein 9
Alias:
10C; MGC1295; RGL1; RHG09; Rho GTPase activating 9; Rho GTPase activating protein 9
Type:
Adhesion
Mass (Da):
83260
Number AA:
750
UniProt ID:
Q9BRR9
International Prot ID:
IPI00747804
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
L
S
S
R
W
W
P
S
S
W
G
I
L
G
L
Site 2
S10
S
S
R
W
W
P
S
S
W
G
I
L
G
L
G
Site 3
S20
I
L
G
L
G
P
R
S
P
P
R
G
S
Q
L
Site 4
S25
P
R
S
P
P
R
G
S
Q
L
C
A
L
Y
A
Site 5
S44
G
A
D
G
Q
Q
V
S
L
A
E
G
D
R
F
Site 6
T57
R
F
L
L
L
R
K
T
N
S
D
W
W
L
A
Site 7
S59
L
L
L
R
K
T
N
S
D
W
W
L
A
R
R
Site 8
S71
A
R
R
L
E
A
P
S
T
S
R
P
I
F
V
Site 9
T72
R
R
L
E
A
P
S
T
S
R
P
I
F
V
P
Site 10
S73
R
L
E
A
P
S
T
S
R
P
I
F
V
P
A
Site 11
S87
A
A
Y
M
I
E
E
S
I
P
S
Q
S
P
T
Site 12
S90
M
I
E
E
S
I
P
S
Q
S
P
T
T
V
I
Site 13
S92
E
E
S
I
P
S
Q
S
P
T
T
V
I
P
G
Site 14
T94
S
I
P
S
Q
S
P
T
T
V
I
P
G
Q
L
Site 15
S113
G
P
K
L
F
H
G
S
L
E
E
L
S
Q
A
Site 16
S118
H
G
S
L
E
E
L
S
Q
A
L
P
S
R
A
Site 17
S123
E
L
S
Q
A
L
P
S
R
A
Q
A
S
S
E
Site 18
S129
P
S
R
A
Q
A
S
S
E
Q
P
P
P
L
P
Site 19
S142
L
P
R
K
M
C
R
S
V
S
T
D
N
L
S
Site 20
S144
R
K
M
C
R
S
V
S
T
D
N
L
S
P
S
Site 21
T145
K
M
C
R
S
V
S
T
D
N
L
S
P
S
L
Site 22
S149
S
V
S
T
D
N
L
S
P
S
L
L
K
P
F
Site 23
S151
S
T
D
N
L
S
P
S
L
L
K
P
F
Q
E
Site 24
S161
K
P
F
Q
E
G
P
S
G
R
S
L
S
Q
E
Site 25
S164
Q
E
G
P
S
G
R
S
L
S
Q
E
D
L
P
Site 26
S166
G
P
S
G
R
S
L
S
Q
E
D
L
P
S
E
Site 27
S172
L
S
Q
E
D
L
P
S
E
A
S
A
S
T
A
Site 28
S175
E
D
L
P
S
E
A
S
A
S
T
A
G
P
Q
Site 29
S177
L
P
S
E
A
S
A
S
T
A
G
P
Q
P
L
Site 30
T178
P
S
E
A
S
A
S
T
A
G
P
Q
P
L
M
Site 31
S186
A
G
P
Q
P
L
M
S
E
P
P
V
Y
C
N
Site 32
Y191
L
M
S
E
P
P
V
Y
C
N
L
V
D
L
R
Site 33
S203
D
L
R
R
C
P
R
S
P
P
P
G
P
A
C
Site 34
Y232
P
N
S
G
R
C
F
Y
I
N
S
L
T
G
C
Site 35
S241
N
S
L
T
G
C
K
S
W
K
P
P
R
R
S
Site 36
S248
S
W
K
P
P
R
R
S
R
S
E
T
N
P
G
Site 37
S250
K
P
P
R
R
S
R
S
E
T
N
P
G
S
M
Site 38
T252
P
R
R
S
R
S
E
T
N
P
G
S
M
E
G
Site 39
S256
R
S
E
T
N
P
G
S
M
E
G
T
Q
T
L
Site 40
T260
N
P
G
S
M
E
G
T
Q
T
L
K
R
N
N
Site 41
T262
G
S
M
E
G
T
Q
T
L
K
R
N
N
D
V
Site 42
S279
P
Q
A
K
G
F
R
S
D
T
G
T
P
E
P
Site 43
T281
A
K
G
F
R
S
D
T
G
T
P
E
P
L
D
Site 44
T283
G
F
R
S
D
T
G
T
P
E
P
L
D
P
Q
Site 45
S292
E
P
L
D
P
Q
G
S
L
S
L
S
Q
R
T
Site 46
S294
L
D
P
Q
G
S
L
S
L
S
Q
R
T
S
Q
Site 47
S296
P
Q
G
S
L
S
L
S
Q
R
T
S
Q
L
D
Site 48
S300
L
S
L
S
Q
R
T
S
Q
L
D
P
P
A
L
Site 49
S326
D
P
H
E
V
E
K
S
G
L
L
N
M
T
K
Site 50
Y360
T
G
N
S
L
V
F
Y
R
E
P
P
P
T
A
Site 51
T366
F
Y
R
E
P
P
P
T
A
P
S
S
G
W
G
Site 52
S369
E
P
P
P
T
A
P
S
S
G
W
G
P
A
G
Site 53
S370
P
P
P
T
A
P
S
S
G
W
G
P
A
G
S
Site 54
S377
S
G
W
G
P
A
G
S
R
P
E
S
S
V
D
Site 55
S381
P
A
G
S
R
P
E
S
S
V
D
L
R
G
A
Site 56
S382
A
G
S
R
P
E
S
S
V
D
L
R
G
A
A
Site 57
S397
L
A
H
G
R
H
L
S
S
R
R
N
V
L
H
Site 58
S398
A
H
G
R
H
L
S
S
R
R
N
V
L
H
I
Site 59
S417
G
H
E
F
L
L
Q
S
D
H
E
T
E
L
R
Site 60
T421
L
L
Q
S
D
H
E
T
E
L
R
A
W
H
R
Site 61
T432
A
W
H
R
A
L
R
T
V
I
E
R
L
V
R
Site 62
T449
E
A
R
R
E
A
P
T
G
R
D
Q
G
S
G
Site 63
S455
P
T
G
R
D
Q
G
S
G
D
R
E
N
P
L
Site 64
S467
N
P
L
E
L
R
L
S
G
S
G
P
A
E
L
Site 65
S469
L
E
L
R
L
S
G
S
G
P
A
E
L
S
A
Site 66
S475
G
S
G
P
A
E
L
S
A
G
E
D
E
E
E
Site 67
S484
G
E
D
E
E
E
E
S
E
L
V
S
K
P
L
Site 68
S488
E
E
E
S
E
L
V
S
K
P
L
L
R
L
S
Site 69
S495
S
K
P
L
L
R
L
S
S
R
R
S
S
I
R
Site 70
S496
K
P
L
L
R
L
S
S
R
R
S
S
I
R
G
Site 71
S499
L
R
L
S
S
R
R
S
S
I
R
G
P
E
G
Site 72
S500
R
L
S
S
R
R
S
S
I
R
G
P
E
G
T
Site 73
T507
S
I
R
G
P
E
G
T
E
Q
N
R
V
R
N
Site 74
S528
A
K
R
P
P
L
Q
S
L
Q
E
R
G
L
L
Site 75
S546
V
F
G
C
Q
L
E
S
L
C
Q
R
E
G
D
Site 76
T554
L
C
Q
R
E
G
D
T
V
P
S
F
L
R
L
Site 77
T600
V
D
R
E
R
A
V
T
S
D
G
R
Y
V
F
Site 78
Y605
A
V
T
S
D
G
R
Y
V
F
P
E
Q
P
G
Site 79
S621
E
G
R
L
D
L
D
S
T
E
W
D
D
I
H
Site 80
T622
G
R
L
D
L
D
S
T
E
W
D
D
I
H
V
Site 81
S668
S
E
S
E
Q
C
L
S
Q
I
Q
E
L
I
G
Site 82
S676
Q
I
Q
E
L
I
G
S
M
P
K
P
N
H
D
Site 83
T684
M
P
K
P
N
H
D
T
L
R
Y
L
L
E
H
Site 84
Y687
P
N
H
D
T
L
R
Y
L
L
E
H
L
C
R
Site 85
S699
L
C
R
V
I
A
H
S
D
K
N
R
M
T
P
Site 86
T705
H
S
D
K
N
R
M
T
P
H
N
L
G
I
V
Site 87
T724
L
F
R
P
E
Q
E
T
S
D
P
A
A
H
A
Site 88
S725
F
R
P
E
Q
E
T
S
D
P
A
A
H
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation