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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPATCH1
Full Name:
G patch domain-containing protein 1
Alias:
Evolutionarily conserved G-patch domain-containing protein
Type:
Mass (Da):
103327
Number AA:
931
UniProt ID:
Q9BRR8
International Prot ID:
IPI00550477
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
A
R
D
S
D
S
E
E
D
L
V
Site 2
S8
M
A
A
R
D
S
D
S
E
E
D
L
V
S
Y
Site 3
S14
D
S
E
E
D
L
V
S
Y
G
T
G
L
E
P
Site 4
T38
P
I
P
L
Q
D
Q
T
V
R
D
E
K
G
R
Site 5
Y46
V
R
D
E
K
G
R
Y
K
R
F
H
G
A
F
Site 6
S54
K
R
F
H
G
A
F
S
G
G
F
S
A
G
Y
Site 7
Y61
S
G
G
F
S
A
G
Y
F
N
T
V
G
S
K
Site 8
T64
F
S
A
G
Y
F
N
T
V
G
S
K
E
G
W
Site 9
S67
G
Y
F
N
T
V
G
S
K
E
G
W
T
P
S
Site 10
T72
V
G
S
K
E
G
W
T
P
S
T
F
V
S
S
Site 11
S74
S
K
E
G
W
T
P
S
T
F
V
S
S
R
Q
Site 12
T75
K
E
G
W
T
P
S
T
F
V
S
S
R
Q
N
Site 13
S78
W
T
P
S
T
F
V
S
S
R
Q
N
R
A
D
Site 14
S87
R
Q
N
R
A
D
K
S
V
L
G
P
E
D
F
Site 15
S101
F
M
D
E
E
D
L
S
E
F
G
I
A
P
K
Site 16
S118
V
T
T
D
D
F
A
S
K
T
K
D
R
I
R
Site 17
T120
T
D
D
F
A
S
K
T
K
D
R
I
R
E
K
Site 18
T135
A
R
Q
L
A
A
A
T
A
P
I
P
G
A
T
Site 19
S154
L
I
T
P
A
K
L
S
V
G
F
E
L
L
R
Site 20
Y191
P
D
P
G
V
K
I
Y
G
C
A
L
P
P
G
Site 21
S199
G
C
A
L
P
P
G
S
S
E
G
S
E
G
E
Site 22
S200
C
A
L
P
P
G
S
S
E
G
S
E
G
E
D
Site 23
S203
P
P
G
S
S
E
G
S
E
G
E
D
D
D
Y
Site 24
Y210
S
E
G
E
D
D
D
Y
L
P
D
N
V
T
F
Site 25
T216
D
Y
L
P
D
N
V
T
F
A
P
K
D
V
T
Site 26
T223
T
F
A
P
K
D
V
T
P
V
D
F
T
P
K
Site 27
T228
D
V
T
P
V
D
F
T
P
K
D
N
V
H
G
Site 28
S259
G
E
H
F
N
L
F
S
G
G
S
E
R
A
G
Site 29
S262
F
N
L
F
S
G
G
S
E
R
A
G
D
L
G
Site 30
S282
K
G
R
K
L
G
I
S
G
Q
A
F
G
V
G
Site 31
Y299
E
E
E
D
D
D
I
Y
A
T
E
T
L
S
K
Site 32
T301
E
D
D
D
I
Y
A
T
E
T
L
S
K
Y
D
Site 33
Y307
A
T
E
T
L
S
K
Y
D
T
V
L
K
D
E
Site 34
T309
E
T
L
S
K
Y
D
T
V
L
K
D
E
E
P
Site 35
Y321
E
E
P
G
D
G
L
Y
G
W
T
A
P
R
Q
Site 36
Y329
G
W
T
A
P
R
Q
Y
K
N
Q
K
E
S
E
Site 37
Y341
E
S
E
K
D
L
R
Y
V
G
K
I
L
D
G
Site 38
S353
L
D
G
F
S
L
A
S
K
P
L
S
S
K
K
Site 39
S357
S
L
A
S
K
P
L
S
S
K
K
I
Y
P
P
Site 40
S358
L
A
S
K
P
L
S
S
K
K
I
Y
P
P
P
Site 41
Y362
P
L
S
S
K
K
I
Y
P
P
P
E
L
P
R
Site 42
Y371
P
P
E
L
P
R
D
Y
R
P
V
H
Y
F
R
Site 43
Y376
R
D
Y
R
P
V
H
Y
F
R
P
M
V
A
A
Site 44
S385
R
P
M
V
A
A
T
S
E
N
S
H
L
L
Q
Site 45
S395
S
H
L
L
Q
V
L
S
E
S
A
G
K
A
T
Site 46
T402
S
E
S
A
G
K
A
T
P
D
P
G
T
H
S
Site 47
T407
K
A
T
P
D
P
G
T
H
S
K
H
Q
L
N
Site 48
S409
T
P
D
P
G
T
H
S
K
H
Q
L
N
A
S
Site 49
S416
S
K
H
Q
L
N
A
S
K
R
A
E
L
L
G
Site 50
T425
R
A
E
L
L
G
E
T
P
I
Q
G
S
A
T
Site 51
S430
G
E
T
P
I
Q
G
S
A
T
S
V
L
E
F
Site 52
S439
T
S
V
L
E
F
L
S
Q
K
D
K
E
R
I
Site 53
S471
S
L
A
Q
N
A
Q
S
S
R
A
Q
L
S
P
Site 54
S472
L
A
Q
N
A
Q
S
S
R
A
Q
L
S
P
A
Site 55
S477
Q
S
S
R
A
Q
L
S
P
A
A
A
A
G
H
Site 56
T497
A
L
G
G
G
T
A
T
L
K
A
S
N
F
K
Site 57
Y516
D
P
E
K
Q
K
R
Y
D
E
F
L
V
H
M
Site 58
S538
L
E
R
C
L
D
P
S
M
T
E
W
E
R
G
Site 59
T540
R
C
L
D
P
S
M
T
E
W
E
R
G
R
E
Site 60
S560
R
A
A
L
L
Y
A
S
S
H
S
T
L
S
S
Site 61
S561
A
A
L
L
Y
A
S
S
H
S
T
L
S
S
R
Site 62
S563
L
L
Y
A
S
S
H
S
T
L
S
S
R
F
T
Site 63
T564
L
Y
A
S
S
H
S
T
L
S
S
R
F
T
H
Site 64
S566
A
S
S
H
S
T
L
S
S
R
F
T
H
A
K
Site 65
S567
S
S
H
S
T
L
S
S
R
F
T
H
A
K
E
Site 66
T570
S
T
L
S
S
R
F
T
H
A
K
E
E
D
D
Site 67
S578
H
A
K
E
E
D
D
S
D
Q
V
E
V
P
R
Site 68
T610
F
G
K
L
T
R
D
T
F
E
W
H
P
D
K
Site 69
Y629
R
F
N
V
P
D
P
Y
P
D
S
T
L
V
G
Site 70
S632
V
P
D
P
Y
P
D
S
T
L
V
G
L
P
R
Site 71
T633
P
D
P
Y
P
D
S
T
L
V
G
L
P
R
V
Site 72
Y645
P
R
V
K
R
D
K
Y
S
V
F
N
F
L
T
Site 73
S646
R
V
K
R
D
K
Y
S
V
F
N
F
L
T
L
Site 74
T656
N
F
L
T
L
P
E
T
A
S
L
P
T
T
Q
Site 75
S658
L
T
L
P
E
T
A
S
L
P
T
T
Q
A
S
Site 76
T662
E
T
A
S
L
P
T
T
Q
A
S
S
E
K
V
Site 77
S665
S
L
P
T
T
Q
A
S
S
E
K
V
S
Q
H
Site 78
S666
L
P
T
T
Q
A
S
S
E
K
V
S
Q
H
R
Site 79
S670
Q
A
S
S
E
K
V
S
Q
H
R
G
P
D
K
Site 80
S678
Q
H
R
G
P
D
K
S
R
K
P
S
R
W
D
Site 81
S682
P
D
K
S
R
K
P
S
R
W
D
T
S
K
H
Site 82
T686
R
K
P
S
R
W
D
T
S
K
H
E
K
K
E
Site 83
S687
K
P
S
R
W
D
T
S
K
H
E
K
K
E
D
Site 84
S695
K
H
E
K
K
E
D
S
I
S
E
F
L
S
L
Site 85
S697
E
K
K
E
D
S
I
S
E
F
L
S
L
A
R
Site 86
S701
D
S
I
S
E
F
L
S
L
A
R
S
K
A
E
Site 87
S705
E
F
L
S
L
A
R
S
K
A
E
P
P
K
Q
Site 88
S715
E
P
P
K
Q
Q
S
S
P
L
V
N
K
E
E
Site 89
T733
P
E
L
S
A
N
Q
T
V
N
K
D
V
D
A
Site 90
S747
A
Q
A
E
G
E
G
S
R
P
S
M
D
L
F
Site 91
S750
E
G
E
G
S
R
P
S
M
D
L
F
R
A
I
Site 92
S760
L
F
R
A
I
F
A
S
S
S
D
E
K
S
S
Site 93
S761
F
R
A
I
F
A
S
S
S
D
E
K
S
S
S
Site 94
S762
R
A
I
F
A
S
S
S
D
E
K
S
S
S
S
Site 95
S766
A
S
S
S
D
E
K
S
S
S
S
E
D
E
Q
Site 96
S767
S
S
S
D
E
K
S
S
S
S
E
D
E
Q
G
Site 97
S768
S
S
D
E
K
S
S
S
S
E
D
E
Q
G
D
Site 98
S769
S
D
E
K
S
S
S
S
E
D
E
Q
G
D
S
Site 99
S776
S
E
D
E
Q
G
D
S
E
D
D
Q
A
G
S
Site 100
S783
S
E
D
D
Q
A
G
S
G
E
A
N
F
Q
S
Site 101
S790
S
G
E
A
N
F
Q
S
S
Q
D
T
D
L
G
Site 102
S791
G
E
A
N
F
Q
S
S
Q
D
T
D
L
G
E
Site 103
T794
N
F
Q
S
S
Q
D
T
D
L
G
E
T
S
S
Site 104
S816
A
P
Q
E
P
P
P
S
F
P
I
Q
K
M
Q
Site 105
T845
F
C
P
N
A
R
Q
T
L
E
V
P
Q
K
E
Site 106
S894
K
N
K
K
P
E
K
S
S
S
S
E
S
S
D
Site 107
S895
N
K
K
P
E
K
S
S
S
S
E
S
S
D
S
Site 108
S896
K
K
P
E
K
S
S
S
S
E
S
S
D
S
S
Site 109
S897
K
P
E
K
S
S
S
S
E
S
S
D
S
S
D
Site 110
S899
E
K
S
S
S
S
E
S
S
D
S
S
D
S
Q
Site 111
S900
K
S
S
S
S
E
S
S
D
S
S
D
S
Q
S
Site 112
S902
S
S
S
E
S
S
D
S
S
D
S
Q
S
D
E
Site 113
S903
S
S
E
S
S
D
S
S
D
S
Q
S
D
E
E
Site 114
S905
E
S
S
D
S
S
D
S
Q
S
D
E
E
T
A
Site 115
S907
S
D
S
S
D
S
Q
S
D
E
E
T
A
D
V
Site 116
T911
D
S
Q
S
D
E
E
T
A
D
V
S
P
Q
E
Site 117
S915
D
E
E
T
A
D
V
S
P
Q
E
L
L
R
R
Site 118
S925
E
L
L
R
R
L
K
S
L
P
L
R
R
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation