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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBL1Y
Full Name:
F-box-like/WD repeat-containing protein TBL1Y
Alias:
Tbl1; Tbl1y; Transducin (beta)-like 1y-linked; Transducin beta-like 1y
Type:
Nucleus protein
Mass (Da):
56688
Number AA:
522
UniProt ID:
Q9BQ87
International Prot ID:
IPI00020873
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
V
N
F
L
V
Y
R
Y
L
Q
E
S
G
F
S
Site 2
S19
V
Y
R
Y
L
Q
E
S
G
F
S
H
S
A
F
Site 3
S22
Y
L
Q
E
S
G
F
S
H
S
A
F
T
F
G
Site 4
S24
Q
E
S
G
F
S
H
S
A
F
T
F
G
I
E
Site 5
S35
F
G
I
E
S
H
I
S
Q
S
N
I
N
G
T
Site 6
S37
I
E
S
H
I
S
Q
S
N
I
N
G
T
L
V
Site 7
T42
S
Q
S
N
I
N
G
T
L
V
P
P
S
A
L
Site 8
S65
Q
Y
V
E
A
E
I
S
I
N
K
D
G
T
V
Site 9
T71
I
S
I
N
K
D
G
T
V
F
D
S
R
P
I
Site 10
S75
K
D
G
T
V
F
D
S
R
P
I
E
S
L
S
Site 11
T113
Q
Q
A
S
A
A
A
T
E
A
S
A
M
A
K
Site 12
S130
T
M
T
P
A
A
I
S
Q
Q
N
P
P
K
N
Site 13
T141
P
P
K
N
R
E
A
T
V
N
G
E
E
N
G
Site 14
S196
P
V
S
D
L
L
A
S
G
S
G
D
S
T
A
Site 15
S198
S
D
L
L
A
S
G
S
G
D
S
T
A
R
I
Site 16
S201
L
A
S
G
S
G
D
S
T
A
R
I
W
N
L
Site 17
T202
A
S
G
S
G
D
S
T
A
R
I
W
N
L
N
Site 18
S216
N
E
N
S
N
G
G
S
T
Q
L
V
L
R
H
Site 19
S234
E
G
G
H
D
V
P
S
N
K
D
V
T
S
L
Site 20
T239
V
P
S
N
K
D
V
T
S
L
D
W
N
S
D
Site 21
S240
P
S
N
K
D
V
T
S
L
D
W
N
S
D
G
Site 22
T248
L
D
W
N
S
D
G
T
L
L
A
M
G
S
Y
Site 23
T263
D
G
F
A
R
I
W
T
E
N
G
N
L
A
S
Site 24
Y290
K
W
N
K
K
G
N
Y
V
L
S
A
G
V
D
Site 25
S293
K
K
G
N
Y
V
L
S
A
G
V
D
K
T
T
Site 26
T300
S
A
G
V
D
K
T
T
I
I
W
D
A
H
T
Site 27
Y405
Q
A
H
S
K
E
I
Y
T
I
K
W
S
P
T
Site 28
T406
A
H
S
K
E
I
Y
T
I
K
W
S
P
T
G
Site 29
S410
E
I
Y
T
I
K
W
S
P
T
G
P
A
T
S
Site 30
T416
W
S
P
T
G
P
A
T
S
N
P
N
S
S
I
Site 31
S417
S
P
T
G
P
A
T
S
N
P
N
S
S
I
M
Site 32
S421
P
A
T
S
N
P
N
S
S
I
M
L
A
S
A
Site 33
S422
A
T
S
N
P
N
S
S
I
M
L
A
S
A
S
Site 34
T433
A
S
A
S
F
D
S
T
V
R
L
W
D
V
E
Site 35
Y456
M
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Site 36
S457
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
G
Site 37
Y466
A
F
S
P
D
G
K
Y
L
A
S
G
S
F
D
Site 38
S471
G
K
Y
L
A
S
G
S
F
D
K
Y
V
H
I
Site 39
Y475
A
S
G
S
F
D
K
Y
V
H
I
W
N
T
Q
Site 40
S485
I
W
N
T
Q
S
G
S
L
V
H
S
Y
Q
G
Site 41
S489
Q
S
G
S
L
V
H
S
Y
Q
G
T
G
G
I
Site 42
Y490
S
G
S
L
V
H
S
Y
Q
G
T
G
G
I
F
Site 43
S511
R
G
D
K
V
G
A
S
A
S
D
G
S
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation