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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCF25
Full Name:
Transcription factor 25
Alias:
Hulp1; Nuclear localized protein 1
Type:
Transcription factor
Mass (Da):
76667
Number AA:
676
UniProt ID:
Q9BQ70
International Prot ID:
IPI00007320
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007507
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
R
R
A
L
R
R
L
Site 2
S81
P
V
V
N
G
E
R
S
G
C
A
L
T
D
A
Site 3
T86
E
R
S
G
C
A
L
T
D
A
V
A
P
G
N
Site 4
T102
G
R
G
Q
R
G
N
T
E
S
K
T
D
G
D
Site 5
S104
G
Q
R
G
N
T
E
S
K
T
D
G
D
D
T
Site 6
T106
R
G
N
T
E
S
K
T
D
G
D
D
T
E
T
Site 7
T111
S
K
T
D
G
D
D
T
E
T
V
P
S
E
Q
Site 8
T113
T
D
G
D
D
T
E
T
V
P
S
E
Q
S
H
Site 9
S116
D
D
T
E
T
V
P
S
E
Q
S
H
A
S
G
Site 10
S119
E
T
V
P
S
E
Q
S
H
A
S
G
K
L
R
Site 11
S137
K
K
Q
K
N
K
K
S
S
T
G
E
A
S
E
Site 12
T139
Q
K
N
K
K
S
S
T
G
E
A
S
E
N
G
Site 13
S160
I
L
E
R
I
E
D
S
T
G
L
N
R
P
G
Site 14
T161
L
E
R
I
E
D
S
T
G
L
N
R
P
G
P
Site 15
S172
R
P
G
P
A
P
L
S
S
R
K
H
V
L
Y
Site 16
S173
P
G
P
A
P
L
S
S
R
K
H
V
L
Y
V
Site 17
Y179
S
S
R
K
H
V
L
Y
V
E
H
R
H
L
N
Site 18
T189
H
R
H
L
N
P
D
T
E
L
K
R
Y
F
G
Site 19
Y194
P
D
T
E
L
K
R
Y
F
G
A
R
A
I
L
Site 20
Y213
P
R
Q
R
Q
R
V
Y
P
K
C
T
W
L
T
Site 21
T221
P
K
C
T
W
L
T
T
P
K
S
T
W
P
R
Site 22
T225
W
L
T
T
P
K
S
T
W
P
R
Y
S
K
P
Site 23
Y229
P
K
S
T
W
P
R
Y
S
K
P
G
L
S
M
Site 24
S230
K
S
T
W
P
R
Y
S
K
P
G
L
S
M
R
Site 25
S235
R
Y
S
K
P
G
L
S
M
R
L
L
E
S
K
Site 26
S246
L
E
S
K
K
G
L
S
F
F
A
F
E
H
S
Site 27
S288
T
S
P
Y
H
V
D
S
L
L
Q
L
S
D
A
Site 28
S293
V
D
S
L
L
Q
L
S
D
A
C
R
F
Q
E
Site 29
S328
H
P
L
F
S
L
T
S
G
A
C
R
L
D
Y
Site 30
Y335
S
G
A
C
R
L
D
Y
R
R
P
E
N
R
S
Site 31
S342
Y
R
R
P
E
N
R
S
F
Y
L
A
L
Y
K
Site 32
Y344
R
P
E
N
R
S
F
Y
L
A
L
Y
K
Q
M
Site 33
Y348
R
S
F
Y
L
A
L
Y
K
Q
M
S
F
L
E
Site 34
S352
L
A
L
Y
K
Q
M
S
F
L
E
K
R
G
C
Site 35
T362
E
K
R
G
C
P
R
T
A
L
E
Y
C
K
L
Site 36
S372
E
Y
C
K
L
I
L
S
L
E
P
D
E
D
P
Site 37
Y398
L
R
A
R
N
Y
E
Y
L
I
R
L
F
Q
E
Site 38
S413
W
E
A
H
R
N
L
S
Q
L
P
N
F
A
F
Site 39
S430
P
L
A
Y
F
L
L
S
Q
Q
T
D
L
P
E
Site 40
S441
D
L
P
E
C
E
Q
S
S
A
R
Q
K
A
S
Site 41
S442
L
P
E
C
E
Q
S
S
A
R
Q
K
A
S
L
Site 42
S448
S
S
A
R
Q
K
A
S
L
L
I
Q
Q
A
L
Site 43
S476
C
S
V
R
P
D
A
S
V
S
S
H
R
F
F
Site 44
S478
V
R
P
D
A
S
V
S
S
H
R
F
F
G
P
Site 45
S479
R
P
D
A
S
V
S
S
H
R
F
F
G
P
N
Site 46
S490
F
G
P
N
A
E
I
S
Q
P
P
A
L
S
Q
Site 47
Y548
E
N
R
R
K
V
L
Y
Q
R
A
P
R
N
I
Site 48
S579
P
P
D
V
T
T
Q
S
V
M
G
F
D
P
L
Site 49
S589
G
F
D
P
L
P
P
S
D
T
I
Y
S
Y
V
Site 50
T591
D
P
L
P
P
S
D
T
I
Y
S
Y
V
R
P
Site 51
Y593
L
P
P
S
D
T
I
Y
S
Y
V
R
P
E
R
Site 52
Y595
P
S
D
T
I
Y
S
Y
V
R
P
E
R
L
S
Site 53
S602
Y
V
R
P
E
R
L
S
P
I
S
H
G
N
T
Site 54
S605
P
E
R
L
S
P
I
S
H
G
N
T
I
A
L
Site 55
Y621
F
R
S
L
L
P
N
Y
T
M
E
G
E
R
P
Site 56
T622
R
S
L
L
P
N
Y
T
M
E
G
E
R
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation