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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGPD5
Full Name:
RANBP2-like and GRIP domain-containing protein 5/6
Alias:
BS-63; DKFZp686I1842; Ran-binding protein 2-like 1; RANBP2L1; RANBP2-like and GRIP domain-containing protein 8; RGP5; Sperm membrane protein BS-63
Type:
Uncharacterized
Mass (Da):
198924
Number AA:
1765
UniProt ID:
Q99666
International Prot ID:
IPI00655887
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0046907
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
V
A
S
V
L
G
L
T
P
S
P
R
Q
K
S
Site 2
S21
S
V
L
G
L
T
P
S
P
R
Q
K
S
M
K
Site 3
Y36
G
F
Y
F
A
K
L
Y
Y
E
A
K
E
Y
D
Site 4
Y42
L
Y
Y
E
A
K
E
Y
D
L
A
K
K
Y
I
Site 5
Y48
E
Y
D
L
A
K
K
Y
I
C
T
Y
I
N
V
Site 6
S86
A
V
E
C
Y
R
R
S
V
E
L
N
P
T
Q
Site 7
T92
R
S
V
E
L
N
P
T
Q
K
D
L
V
L
K
Site 8
S177
R
L
V
E
L
Y
R
S
T
K
R
L
K
D
A
Site 9
S217
T
L
K
E
Y
L
E
S
L
Q
C
L
E
S
D
Site 10
S248
N
L
M
L
L
T
L
S
T
R
D
V
Q
E
N
Site 11
S264
E
L
L
E
S
F
D
S
A
L
Q
S
A
K
S
Site 12
S268
S
F
D
S
A
L
Q
S
A
K
S
S
L
G
G
Site 13
S272
A
L
Q
S
A
K
S
S
L
G
G
N
D
E
L
Site 14
S361
Q
S
G
H
M
L
L
S
L
S
R
G
K
Q
D
Site 15
S363
G
H
M
L
L
S
L
S
R
G
K
Q
D
F
L
Site 16
Y387
K
I
G
Q
S
A
L
Y
D
A
L
F
S
S
Q
Site 17
S393
L
Y
D
A
L
F
S
S
Q
S
P
K
D
T
S
Site 18
S404
K
D
T
S
F
L
G
S
D
D
I
G
K
I
D
Site 19
T469
F
H
R
L
P
H
E
T
S
R
L
E
T
N
A
Site 20
S588
K
Y
L
Q
K
T
G
S
G
L
N
S
F
Y
G
Site 21
Y594
G
S
G
L
N
S
F
Y
G
Q
L
E
Y
I
G
Site 22
T669
G
N
I
E
D
A
V
T
A
F
E
S
I
K
S
Site 23
S700
D
I
E
N
D
A
L
S
P
E
E
Q
E
E
C
Site 24
S741
K
L
P
V
P
L
E
S
V
K
Q
M
L
N
S
Site 25
Y763
Y
S
E
G
G
P
L
Y
K
N
G
S
L
R
N
Site 26
S767
G
P
L
Y
K
N
G
S
L
R
N
A
D
S
E
Site 27
S773
G
S
L
R
N
A
D
S
E
I
K
H
S
T
P
Site 28
S781
E
I
K
H
S
T
P
S
P
T
K
Y
S
L
S
Site 29
Y785
S
T
P
S
P
T
K
Y
S
L
S
P
S
K
S
Site 30
S788
S
P
T
R
Y
S
L
S
P
S
K
S
Y
K
Y
Site 31
S796
P
S
K
S
Y
K
Y
S
P
E
T
P
P
R
W
Site 32
S833
Q
E
L
K
L
N
S
S
K
S
A
S
R
H
R
Site 33
Y846
H
R
W
P
T
E
N
Y
G
P
D
S
V
P
D
Site 34
Y855
P
D
S
V
P
D
G
Y
Q
G
S
Q
T
F
H
Site 35
T860
D
G
Y
Q
G
S
Q
T
F
H
G
A
P
L
T
Site 36
S874
T
V
A
T
T
G
P
S
V
Y
Y
S
Q
S
P
Site 37
S878
T
G
P
S
V
Y
Y
S
Q
S
P
A
Y
N
S
Site 38
S880
P
S
V
Y
Y
S
Q
S
P
A
Y
N
S
Q
Y
Site 39
Y883
Y
Y
S
Q
S
P
A
Y
N
S
Q
Y
L
L
R
Site 40
S914
K
S
T
K
E
G
F
S
I
P
V
S
A
D
G
Site 41
S927
D
G
F
K
F
G
I
S
E
P
G
N
Q
E
K
Site 42
S979
A
D
V
A
K
S
T
S
G
E
G
F
Q
F
G
Site 43
S1004
G
A
G
E
K
L
F
S
S
R
Y
G
K
M
A
Site 44
S1005
A
G
E
K
L
F
S
S
R
Y
G
K
M
A
N
Site 45
T1029
K
D
D
D
A
Y
K
T
E
D
S
D
D
I
H
Site 46
Y1060
E
E
G
E
K
V
L
Y
S
Q
G
V
K
L
F
Site 47
S1061
E
G
E
K
V
L
Y
S
Q
G
V
K
L
F
R
Site 48
S1125
N
L
K
P
L
S
G
S
D
R
A
W
M
W
S
Site 49
S1132
S
D
R
A
W
M
W
S
A
S
D
F
S
D
G
Site 50
S1134
R
A
W
M
W
S
A
S
D
F
S
D
G
D
A
Site 51
T1152
R
L
A
A
K
F
K
T
P
E
L
A
E
E
F
Site 52
T1177
L
L
D
I
P
L
Q
T
P
H
K
L
V
D
T
Site 53
S1199
Q
R
A
E
E
M
K
S
G
L
K
D
F
K
T
Site 54
T1206
S
G
L
K
D
F
K
T
F
L
T
N
D
Q
T
Site 55
T1234
A
A
G
A
S
D
T
T
I
K
P
N
A
E
N
Site 56
Y1251
P
T
L
E
W
D
N
Y
D
L
R
E
D
A
L
Site 57
S1263
D
A
L
D
D
S
V
S
S
S
S
V
H
A
S
Site 58
S1264
A
L
D
D
S
V
S
S
S
S
V
H
A
S
P
Site 59
S1266
D
D
S
V
S
S
S
S
V
H
A
S
P
L
A
Site 60
S1275
H
A
S
P
L
A
S
S
P
V
R
K
N
L
F
Site 61
S1287
N
L
F
R
F
D
E
S
T
T
G
S
N
F
S
Site 62
T1288
L
F
R
F
D
E
S
T
T
G
S
N
F
S
F
Site 63
S1291
F
D
E
S
T
T
G
S
N
F
S
F
K
S
A
Site 64
S1294
S
T
T
G
S
N
F
S
F
K
S
A
L
S
L
Site 65
S1297
G
S
N
F
S
F
K
S
A
L
S
L
S
K
S
Site 66
S1302
F
K
S
A
L
S
L
S
K
S
P
A
K
L
N
Site 67
S1304
S
A
L
S
L
S
K
S
P
A
K
L
N
Q
S
Site 68
T1324
T
D
E
E
S
V
V
T
Q
E
E
E
R
D
G
Site 69
S1358
E
N
E
Q
V
V
F
S
H
R
A
E
I
Y
R
Site 70
Y1366
H
R
A
E
I
Y
R
Y
D
K
D
V
G
Q
W
Site 71
Y1387
D
I
K
I
L
Q
N
Y
D
N
K
Q
V
R
I
Site 72
S1415
H
R
I
T
P
D
M
S
L
Q
N
M
K
G
T
Site 73
S1455
K
L
Q
D
V
A
D
S
F
K
K
I
F
D
E
Site 74
S1471
K
T
A
Q
E
K
D
S
L
I
T
P
H
V
S
Site 75
T1474
Q
E
K
D
S
L
I
T
P
H
V
S
R
S
S
Site 76
S1478
S
L
I
T
P
H
V
S
R
S
S
T
P
R
E
Site 77
S1480
I
T
P
H
V
S
R
S
S
T
P
R
E
S
P
Site 78
S1486
R
S
S
T
P
R
E
S
P
C
G
K
I
A
V
Site 79
T1504
E
E
T
T
R
E
R
T
D
V
I
Q
G
D
D
Site 80
S1522
A
A
S
E
V
E
V
S
S
T
S
E
T
T
T
Site 81
T1529
S
S
T
S
E
T
T
T
K
A
V
V
S
P
P
Site 82
S1550
E
S
V
K
R
I
F
S
S
E
K
S
K
P
F
Site 83
S1551
S
V
K
R
I
F
S
S
E
K
S
K
P
F
V
Site 84
S1554
R
I
F
S
S
E
K
S
K
P
F
V
F
G
N
Site 85
S1579
S
F
N
A
P
L
K
S
N
N
S
E
T
S
S
Site 86
S1582
A
P
L
K
S
N
N
S
E
T
S
S
V
A
Q
Site 87
S1590
E
T
S
S
V
A
Q
S
G
S
E
S
K
V
E
Site 88
S1592
S
S
V
A
Q
S
G
S
E
S
K
V
E
P
K
Site 89
S1594
V
A
Q
S
G
S
E
S
K
V
E
P
K
K
C
Site 90
S1607
K
C
E
L
S
K
N
S
D
I
E
Q
S
S
D
Site 91
S1615
D
I
E
Q
S
S
D
S
K
V
K
N
L
S
A
Site 92
S1621
D
S
K
V
K
N
L
S
A
S
F
P
T
E
E
Site 93
Y1633
T
E
E
S
S
I
N
Y
T
F
K
T
P
E
K
Site 94
T1637
S
I
N
Y
T
F
K
T
P
E
K
E
P
P
L
Site 95
S1660
E
L
V
Q
K
L
R
S
T
T
K
S
A
D
H
Site 96
T1661
L
V
Q
K
L
R
S
T
T
K
S
A
D
H
L
Site 97
S1664
K
L
R
S
T
T
K
S
A
D
H
L
N
G
L
Site 98
Y1711
K
S
A
A
N
L
E
Y
L
K
N
V
L
L
Q
Site 99
S1742
I
N
T
M
L
Q
L
S
P
E
E
K
G
K
L
Site 100
S1761
Q
D
E
E
E
N
A
S
R
S
S
G
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation