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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHB2
Full Name:
Prohibitin-2
Alias:
B-cell receptor associated protein; B-cell receptor-associated protein 37; B-cell receptor-associated protein BAP37; D-prohibitin; HBAP; REA; Repressor of estrogen receptor activity
Type:
Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Mass (Da):
33296
Number AA:
299
UniProt ID:
Q99623
International Prot ID:
IPI00027252
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0004872
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
A
G
P
R
G
M
G
T
A
L
K
L
L
L
G
Site 2
Y34
L
G
A
G
A
V
A
Y
G
V
R
E
S
V
F
Site 3
T42
G
V
R
E
S
V
F
T
V
E
G
G
H
R
A
Site 4
Y77
F
R
I
P
W
F
Q
Y
P
I
I
Y
D
I
R
Site 5
Y81
W
F
Q
Y
P
I
I
Y
D
I
R
A
R
P
R
Site 6
S91
R
A
R
P
R
K
I
S
S
P
T
G
S
K
D
Site 7
S92
A
R
P
R
K
I
S
S
P
T
G
S
K
D
L
Site 8
S96
K
I
S
S
P
T
G
S
K
D
L
Q
M
V
N
Site 9
S110
N
I
S
L
R
V
L
S
R
P
N
A
Q
E
L
Site 10
S119
P
N
A
Q
E
L
P
S
M
Y
Q
R
L
G
L
Site 11
Y121
A
Q
E
L
P
S
M
Y
Q
R
L
G
L
D
Y
Site 12
Y128
Y
Q
R
L
G
L
D
Y
E
E
R
V
L
P
S
Site 13
S135
Y
E
E
R
V
L
P
S
I
V
N
E
V
L
K
Site 14
S151
V
V
A
K
F
N
A
S
Q
L
I
T
Q
R
A
Site 15
T155
F
N
A
S
Q
L
I
T
Q
R
A
Q
V
S
L
Site 16
S161
I
T
Q
R
A
Q
V
S
L
L
I
R
R
E
L
Site 17
T169
L
L
I
R
R
E
L
T
E
R
A
K
D
F
S
Site 18
S176
T
E
R
A
K
D
F
S
L
I
L
D
D
V
A
Site 19
S188
D
V
A
I
T
E
L
S
F
S
R
E
Y
T
A
Site 20
Y193
E
L
S
F
S
R
E
Y
T
A
A
V
E
A
K
Site 21
T194
L
S
F
S
R
E
Y
T
A
A
V
E
A
K
Q
Site 22
S243
K
M
L
G
E
A
L
S
K
N
P
G
Y
I
K
Site 23
Y248
A
L
S
K
N
P
G
Y
I
K
L
R
K
I
R
Site 24
T263
A
A
Q
N
I
S
K
T
I
A
T
S
Q
N
R
Site 25
S267
I
S
K
T
I
A
T
S
Q
N
R
I
Y
L
T
Site 26
Y272
A
T
S
Q
N
R
I
Y
L
T
A
D
N
L
V
Site 27
S286
V
L
N
L
Q
D
E
S
F
T
R
G
S
D
S
Site 28
T288
N
L
Q
D
E
S
F
T
R
G
S
D
S
L
I
Site 29
S291
D
E
S
F
T
R
G
S
D
S
L
I
K
G
K
Site 30
S293
S
F
T
R
G
S
D
S
L
I
K
G
K
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation