PhosphoNET

           
Protein Info 
   
Short Name:  SPSB2
Full Name:  SPRY domain-containing SOCS box protein 2
Alias:  Gene-rich cluster protein C9
Type: 
Mass (Da):  28630
Number AA:  263
UniProt ID:  Q99619
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11TALAGGSSSTPTPQA
Site 2S12ALAGGSSSTPTPQAL
Site 3T13LAGGSSSTPTPQALY
Site 4T15GGSSSTPTPQALYPD
Site 5Y20TPTPQALYPDLSCPE
Site 6S24QALYPDLSCPEGLEE
Site 7S34EGLEELLSAPPPDLG
Site 8S54GWNPKDCSENIEVKE
Site 9Y65EVKEGGLYFERRPVA
Site 10S74ERRPVAQSTDGARGK
Site 11Y84GARGKRGYSRGLHAW
Site 12S85ARGKRGYSRGLHAWE
Site 13Y120APLQTDHYAALLGSN
Site 14S126HYAALLGSNSESWGW
Site 15S128AALLGSNSESWGWDI
Site 16S130LLGSNSESWGWDIGR
Site 17Y141DIGRGKLYHQSKGPG
Site 18S144RGKLYHQSKGPGAPQ
Site 19Y152KGPGAPQYPAGTQGE
Site 20T198FRGLKGRTLYPAVSA
Site 21Y216QCQVRIRYLGERRAE
Site 22S226ERRAEPHSLLHLSRL
Site 23S231PHSLLHLSRLCVRHN
Site 24S248DTRLGQVSALPLPPA
Site 25Y259LPPAMKRYLLYQ___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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