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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTC1
Full Name:
Tetratricopeptide repeat protein 1
Alias:
Tetratricopeptide repeat 1; Tetratricopeptide repeat domain 1; TPR repeat 1; TPR repeat protein 1; TPR1
Type:
Adaptor/scaffold
Mass (Da):
33526
Number AA:
292
UniProt ID:
Q99614
International Prot ID:
IPI00016912
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
N
G
L
K
V
T
D
T
Q
E
A
E
C
A
G
Site 2
S41
P
D
P
K
N
Q
H
S
Q
S
K
L
L
R
D
Site 3
S67
E
E
C
F
H
D
C
S
A
S
F
E
E
E
P
Site 4
S69
C
F
H
D
C
S
A
S
F
E
E
E
P
G
A
Site 5
S83
A
D
K
V
E
N
K
S
N
E
D
V
N
S
S
Site 6
S89
K
S
N
E
D
V
N
S
S
E
L
D
E
E
Y
Site 7
S90
S
N
E
D
V
N
S
S
E
L
D
E
E
Y
L
Site 8
Y96
S
S
E
L
D
E
E
Y
L
I
E
L
E
K
N
Site 9
S105
I
E
L
E
K
N
M
S
D
E
E
K
Q
K
R
Site 10
S116
K
Q
K
R
R
E
E
S
T
R
L
K
E
E
G
Site 11
T117
Q
K
R
R
E
E
S
T
R
L
K
E
E
G
N
Site 12
Y132
E
Q
F
K
K
G
D
Y
I
E
A
E
S
S
Y
Site 13
S138
D
Y
I
E
A
E
S
S
Y
S
R
A
L
E
M
Site 14
S140
I
E
A
E
S
S
Y
S
R
A
L
E
M
C
P
Site 15
S148
R
A
L
E
M
C
P
S
C
F
Q
K
E
R
S
Site 16
S155
S
C
F
Q
K
E
R
S
I
L
F
S
N
R
A
Site 17
S159
K
E
R
S
I
L
F
S
N
R
A
A
A
R
M
Site 18
Y188
A
I
Q
L
N
P
S
Y
I
R
A
I
L
R
R
Site 19
Y199
I
L
R
R
A
E
L
Y
E
K
T
D
K
L
D
Site 20
Y212
L
D
E
A
L
E
D
Y
K
S
I
L
E
K
D
Site 21
S214
E
A
L
E
D
Y
K
S
I
L
E
K
D
P
S
Site 22
S221
S
I
L
E
K
D
P
S
I
H
Q
A
R
E
A
Site 23
S265
V
L
R
P
F
G
L
S
T
E
N
F
Q
I
K
Site 24
S275
N
F
Q
I
K
Q
D
S
S
T
G
S
Y
S
I
Site 25
S276
F
Q
I
K
Q
D
S
S
T
G
S
Y
S
I
N
Site 26
T277
Q
I
K
Q
D
S
S
T
G
S
Y
S
I
N
F
Site 27
S279
K
Q
D
S
S
T
G
S
Y
S
I
N
F
V
Q
Site 28
Y280
Q
D
S
S
T
G
S
Y
S
I
N
F
V
Q
N
Site 29
S281
D
S
S
T
G
S
Y
S
I
N
F
V
Q
N
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation