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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MMP19
Full Name:
Matrix metalloproteinase-19
Alias:
Matrix metalloproteinase RASI;Matrix metalloproteinase-18
Type:
Mass (Da):
57357
Number AA:
508
UniProt ID:
Q99542
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
V
A
P
V
D
Y
L
S
Q
Y
G
Y
L
Q
K
Site 2
Y35
P
V
D
Y
L
S
Q
Y
G
Y
L
Q
K
P
L
Site 3
Y37
D
Y
L
S
Q
Y
G
Y
L
Q
K
P
L
E
G
Site 4
T54
N
F
K
P
E
D
I
T
E
A
L
R
A
F
Q
Site 5
S64
L
R
A
F
Q
E
A
S
E
L
P
V
S
G
Q
Site 6
S69
E
A
S
E
L
P
V
S
G
Q
L
D
D
A
T
Site 7
T76
S
G
Q
L
D
D
A
T
R
A
R
M
R
Q
P
Site 8
T95
E
D
P
F
N
Q
K
T
L
K
Y
L
L
L
G
Site 9
Y98
F
N
Q
K
T
L
K
Y
L
L
L
G
R
W
R
Site 10
T110
R
W
R
K
K
H
L
T
F
R
I
L
N
L
P
Site 11
T119
R
I
L
N
L
P
S
T
L
P
P
H
T
A
R
Site 12
T124
P
S
T
L
P
P
H
T
A
R
A
A
L
R
Q
Site 13
T143
W
S
N
V
A
P
L
T
F
Q
E
V
Q
A
G
Site 14
S157
G
A
A
D
I
R
L
S
F
H
G
R
Q
S
S
Site 15
S163
L
S
F
H
G
R
Q
S
S
Y
C
S
N
T
F
Site 16
S164
S
F
H
G
R
Q
S
S
Y
C
S
N
T
F
D
Site 17
S167
G
R
Q
S
S
Y
C
S
N
T
F
D
G
P
G
Site 18
T169
Q
S
S
Y
C
S
N
T
F
D
G
P
G
R
V
Site 19
T200
D
E
F
W
T
E
G
T
Y
R
G
V
N
L
R
Site 20
S223
H
A
L
G
L
G
H
S
R
Y
S
Q
A
L
M
Site 21
Y225
L
G
L
G
H
S
R
Y
S
Q
A
L
M
A
P
Site 22
S226
G
L
G
H
S
R
Y
S
Q
A
L
M
A
P
V
Site 23
Y234
Q
A
L
M
A
P
V
Y
E
G
Y
R
P
H
F
Site 24
S259
Q
A
L
Y
G
K
K
S
P
V
I
R
D
E
E
Site 25
T270
R
D
E
E
E
E
E
T
E
L
P
T
V
P
P
Site 26
T274
E
E
E
T
E
L
P
T
V
P
P
V
P
T
E
Site 27
S283
P
P
V
P
T
E
P
S
P
M
P
D
P
C
S
Site 28
S290
S
P
M
P
D
P
C
S
S
E
L
D
A
M
M
Site 29
T304
M
L
G
P
R
G
K
T
Y
A
F
K
G
D
Y
Site 30
Y305
L
G
P
R
G
K
T
Y
A
F
K
G
D
Y
V
Site 31
Y311
T
Y
A
F
K
G
D
Y
V
W
T
V
S
D
S
Site 32
T314
F
K
G
D
Y
V
W
T
V
S
D
S
G
P
G
Site 33
S316
G
D
Y
V
W
T
V
S
D
S
G
P
G
P
L
Site 34
S318
Y
V
W
T
V
S
D
S
G
P
G
P
L
F
R
Site 35
Y342
G
N
L
D
A
A
V
Y
S
P
R
T
Q
W
I
Site 36
Y360
K
G
D
K
V
W
R
Y
I
N
F
K
M
S
P
Site 37
S366
R
Y
I
N
F
K
M
S
P
G
F
P
K
K
L
Site 38
Y385
P
N
L
D
A
A
L
Y
W
P
L
N
Q
K
V
Site 39
T409
Q
W
D
E
L
A
R
T
D
F
S
S
Y
P
K
Site 40
S412
E
L
A
R
T
D
F
S
S
Y
P
K
P
I
K
Site 41
S413
L
A
R
T
D
F
S
S
Y
P
K
P
I
K
G
Site 42
Y414
A
R
T
D
F
S
S
Y
P
K
P
I
K
G
L
Site 43
T423
K
P
I
K
G
L
F
T
G
V
P
N
Q
P
S
Site 44
S430
T
G
V
P
N
Q
P
S
A
A
M
S
W
Q
D
Site 45
S434
N
Q
P
S
A
A
M
S
W
Q
D
G
R
V
Y
Site 46
Y441
S
W
Q
D
G
R
V
Y
F
F
K
G
K
V
Y
Site 47
Y448
Y
F
F
K
G
K
V
Y
W
R
L
N
Q
Q
L
Site 48
Y461
Q
L
R
V
E
K
G
Y
P
R
N
I
S
H
N
Site 49
T476
W
M
H
C
R
P
R
T
I
D
T
T
P
S
G
Site 50
T479
C
R
P
R
T
I
D
T
T
P
S
G
G
N
T
Site 51
T480
R
P
R
T
I
D
T
T
P
S
G
G
N
T
T
Site 52
S482
R
T
I
D
T
T
P
S
G
G
N
T
T
P
S
Site 53
T486
T
T
P
S
G
G
N
T
T
P
S
G
T
G
I
Site 54
T487
T
P
S
G
G
N
T
T
P
S
G
T
G
I
T
Site 55
S489
S
G
G
N
T
T
P
S
G
T
G
I
T
L
D
Site 56
T498
T
G
I
T
L
D
T
T
L
S
A
T
E
T
T
Site 57
S500
I
T
L
D
T
T
L
S
A
T
E
T
T
F
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation