PhosphoNET

           
Protein Info 
   
Short Name:  VAT1
Full Name:  Synaptic vesicle membrane protein VAT-1 homolog
Alias:  Chromosome 17q21 mRNA clone 694:2.; Synaptic vesicle membrane protein VAT-1
Type:  Enzyme - Oxidoreductase. Zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Mass (Da):  41920
Number AA:  393
UniProt ID:  Q99536
International Prot ID:  IPI00156689
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0016491  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0055114     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S17AATGEDASSPPPKTE
Site 2S18ATGEDASSPPPKTEA
Site 3T23ASSPPPKTEAASDPQ
Site 4S27PPKTEAASDPQHPAA
Site 5S44GAAAAAASPPLLRCL
Site 6Y59VLTGFGGYDKVKLQS
Site 7T80APGPGQLTLRLRACG
Site 8Y100LMARQGLYDRLPPLP
Site 9T109RLPPLPVTPGMEGAG
Site 10S126IAVGEGVSDRKAGDR
Site 11T211AAVQLCRTVENVTVF
Site 12T220ENVTVFGTASASKHE
Site 13T235ALKENGVTHPIDYHT
Site 14Y240GVTHPIDYHTTDYVD
Site 15Y245IDYHTTDYVDEIKKI
Site 16S253VDEIKKISPKGVDIV
Site 17S267VMDPLGGSDTAKGYN
Site 18T269DPLGGSDTAKGYNLL
Site 19Y273GSDTAKGYNLLKPMG
Site 20T292YGMANLLTGPKRNLM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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