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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R16B
Full Name:
Protein phosphatase 1 regulatory inhibitor subunit 16B
Alias:
ANKRD4; Ankyrin repeat domain 4; Ankyrin repeat domain protein 4; CAAX box TIMAP; KIAA0823; PP16B; Protein phosphatase 1 regulatory inhibitor 16B; Protein phosphatase 1, regulatory (inhibitor) subunit 16B; TGF-beta-inhibited membrane-associated; TGF-beta-inhibited membrane-associated protein; TIMAP
Type:
Protein phosphatase, regulatory subunit
Mass (Da):
63551
Number AA:
567
UniProt ID:
Q96T49
International Prot ID:
IPI00045904
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0019903
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
Q
L
L
E
K
V
P
T
L
E
R
L
R
A
A
Site 2
Y40
Q
L
K
K
W
A
Q
Y
E
Q
D
L
Q
H
R
Site 3
S56
R
K
H
E
R
K
R
S
T
G
G
R
R
K
K
Site 4
T57
K
H
E
R
K
R
S
T
G
G
R
R
K
K
V
Site 5
S65
G
G
R
R
K
K
V
S
F
E
A
S
V
A
L
Site 6
S69
K
K
V
S
F
E
A
S
V
A
L
L
E
A
S
Site 7
S76
S
V
A
L
L
E
A
S
L
R
N
D
A
E
E
Site 8
Y86
N
D
A
E
E
V
R
Y
F
L
K
N
K
V
S
Site 9
S93
Y
F
L
K
N
K
V
S
P
D
L
C
N
E
D
Site 10
T136
A
K
D
N
E
L
W
T
P
L
H
A
A
A
T
Site 11
S165
A
D
L
L
A
V
N
S
D
G
N
M
P
Y
D
Site 12
T179
D
L
C
E
D
E
P
T
L
D
V
I
E
T
C
Site 13
S289
V
S
H
G
A
S
L
S
A
R
T
S
M
D
E
Site 14
S293
A
S
L
S
A
R
T
S
M
D
E
M
P
I
D
Site 15
S324
K
H
D
V
I
M
K
S
Q
L
R
H
K
S
S
Site 16
S330
K
S
Q
L
R
H
K
S
S
L
S
R
R
T
S
Site 17
S331
S
Q
L
R
H
K
S
S
L
S
R
R
T
S
S
Site 18
S333
L
R
H
K
S
S
L
S
R
R
T
S
S
A
G
Site 19
T336
K
S
S
L
S
R
R
T
S
S
A
G
S
R
G
Site 20
S337
S
S
L
S
R
R
T
S
S
A
G
S
R
G
K
Site 21
S338
S
L
S
R
R
T
S
S
A
G
S
R
G
K
V
Site 22
S341
R
R
T
S
S
A
G
S
R
G
K
V
V
R
R
Site 23
S350
G
K
V
V
R
R
A
S
L
S
D
R
T
N
L
Site 24
S352
V
V
R
R
A
S
L
S
D
R
T
N
L
Y
R
Site 25
Y358
L
S
D
R
T
N
L
Y
R
K
E
Y
E
G
E
Site 26
Y362
T
N
L
Y
R
K
E
Y
E
G
E
A
I
L
W
Site 27
T379
S
A
A
E
D
Q
R
T
S
T
Y
N
G
D
I
Site 28
S380
A
A
E
D
Q
R
T
S
T
Y
N
G
D
I
R
Site 29
T381
A
E
D
Q
R
T
S
T
Y
N
G
D
I
R
E
Site 30
Y382
E
D
Q
R
T
S
T
Y
N
G
D
I
R
E
T
Site 31
T389
Y
N
G
D
I
R
E
T
R
T
D
Q
E
N
K
Site 32
Y435
L
R
A
P
V
S
A
Y
Q
Y
A
L
A
N
G
Site 33
Y437
A
P
V
S
A
Y
Q
Y
A
L
A
N
G
D
V
Site 34
Y453
K
V
H
E
V
P
D
Y
S
M
A
Y
G
N
P
Site 35
Y457
V
P
D
Y
S
M
A
Y
G
N
P
G
V
A
D
Site 36
T466
N
P
G
V
A
D
A
T
P
P
W
S
S
Y
K
Site 37
S470
A
D
A
T
P
P
W
S
S
Y
K
E
Q
S
P
Site 38
Y472
A
T
P
P
W
S
S
Y
K
E
Q
S
P
Q
T
Site 39
S476
W
S
S
Y
K
E
Q
S
P
Q
T
L
L
E
L
Site 40
S494
R
A
A
A
K
L
L
S
H
P
F
L
S
T
H
Site 41
S505
L
S
T
H
L
G
S
S
M
A
R
T
G
E
S
Site 42
T509
L
G
S
S
M
A
R
T
G
E
S
S
S
E
G
Site 43
S513
M
A
R
T
G
E
S
S
S
E
G
K
A
P
L
Site 44
S514
A
R
T
G
E
S
S
S
E
G
K
A
P
L
I
Site 45
T525
A
P
L
I
G
G
R
T
S
P
Y
S
S
N
G
Site 46
S526
P
L
I
G
G
R
T
S
P
Y
S
S
N
G
T
Site 47
Y528
I
G
G
R
T
S
P
Y
S
S
N
G
T
S
V
Site 48
S529
G
G
R
T
S
P
Y
S
S
N
G
T
S
V
Y
Site 49
S530
G
R
T
S
P
Y
S
S
N
G
T
S
V
Y
Y
Site 50
T533
S
P
Y
S
S
N
G
T
S
V
Y
Y
T
V
T
Site 51
S534
P
Y
S
S
N
G
T
S
V
Y
Y
T
V
T
S
Site 52
Y536
S
S
N
G
T
S
V
Y
Y
T
V
T
S
G
D
Site 53
Y537
S
N
G
T
S
V
Y
Y
T
V
T
S
G
D
P
Site 54
T538
N
G
T
S
V
Y
Y
T
V
T
S
G
D
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation