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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADO
Full Name:
2-aminoethanethiol dioxygenase
Alias:
AEDO; Chromosome 10 open reading frame 22; Cysteamine dioxygenase; EC 1.13.11.19; FLJ14547
Type:
Oxidoreductase
Mass (Da):
29751
Number AA:
270
UniProt ID:
Q96SZ5
International Prot ID:
IPI00045939
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0047800
GO:0005506
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
R
D
N
M
A
S
L
I
Q
R
I
A
R
Site 2
S24
A
C
L
T
F
R
G
S
G
G
G
R
G
A
S
Site 3
S31
S
G
G
G
R
G
A
S
D
R
D
A
A
S
G
Site 4
S37
A
S
D
R
D
A
A
S
G
P
E
A
P
M
Q
Site 5
S52
P
G
F
P
E
N
L
S
K
L
K
S
L
L
T
Site 6
S56
E
N
L
S
K
L
K
S
L
L
T
Q
L
R
A
Site 7
T59
S
K
L
K
S
L
L
T
Q
L
R
A
E
D
L
Site 8
T74
N
I
A
P
R
K
A
T
L
Q
P
L
P
P
N
Site 9
T86
P
P
N
L
P
P
V
T
Y
M
H
I
Y
E
T
Site 10
Y87
P
N
L
P
P
V
T
Y
M
H
I
Y
E
T
D
Site 11
Y91
P
V
T
Y
M
H
I
Y
E
T
D
G
F
S
L
Site 12
S108
F
L
L
K
S
G
T
S
I
P
L
H
D
H
P
Site 13
S172
V
R
P
G
V
L
R
S
R
A
E
Y
T
E
A
Site 14
Y176
V
L
R
S
R
A
E
Y
T
E
A
S
G
P
C
Site 15
T177
L
R
S
R
A
E
Y
T
E
A
S
G
P
C
I
Site 16
T186
A
S
G
P
C
I
L
T
P
H
R
D
N
L
H
Site 17
Y212
L
D
I
L
A
P
P
Y
D
P
D
D
G
R
D
Site 18
Y222
D
D
G
R
D
C
H
Y
Y
R
V
L
E
P
V
Site 19
Y223
D
G
R
D
C
H
Y
Y
R
V
L
E
P
V
R
Site 20
S235
P
V
R
P
K
E
A
S
S
S
A
C
D
L
P
Site 21
S237
R
P
K
E
A
S
S
S
A
C
D
L
P
R
E
Site 22
T250
R
E
V
W
L
L
E
T
P
Q
A
D
D
F
W
Site 23
Y263
F
W
C
E
G
E
P
Y
P
G
P
K
V
F
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation