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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCNX
Full Name:
Pecanex-like protein 1
Alias:
KIAA0805; KIAA0995; PCNXL1; PCX1; Pecanex
Type:
Unknown function
Mass (Da):
258680
Number AA:
UniProt ID:
Q96RV3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
A
A
L
S
G
G
W
Y
Y
D
P
H
Q
A
T
Site 2
Y23
A
L
S
G
G
W
Y
Y
D
P
H
Q
A
T
F
Site 3
T94
A
G
E
V
V
D
R
T
A
N
E
F
T
D
Q
Site 4
T99
D
R
T
A
N
E
F
T
D
Q
R
T
K
A
E
Site 5
T103
N
E
F
T
D
Q
R
T
K
A
E
Q
G
N
C
Site 6
S111
K
A
E
Q
G
N
C
S
T
R
R
K
D
S
N
Site 7
T112
A
E
Q
G
N
C
S
T
R
R
K
D
S
N
G
Site 8
S117
C
S
T
R
R
K
D
S
N
G
P
S
D
P
G
Site 9
S121
R
K
D
S
N
G
P
S
D
P
G
G
G
I
E
Site 10
S130
P
G
G
G
I
E
M
S
E
F
I
R
E
A
T
Site 11
T137
S
E
F
I
R
E
A
T
P
P
V
G
C
S
S
Site 12
S143
A
T
P
P
V
G
C
S
S
R
N
S
Y
A
G
Site 13
S144
T
P
P
V
G
C
S
S
R
N
S
Y
A
G
L
Site 14
S147
V
G
C
S
S
R
N
S
Y
A
G
L
D
P
S
Site 15
Y148
G
C
S
S
R
N
S
Y
A
G
L
D
P
S
N
Site 16
S154
S
Y
A
G
L
D
P
S
N
Q
I
G
S
G
S
Site 17
S159
D
P
S
N
Q
I
G
S
G
S
S
R
L
G
T
Site 18
S161
S
N
Q
I
G
S
G
S
S
R
L
G
T
A
A
Site 19
T166
S
G
S
S
R
L
G
T
A
A
T
I
K
G
D
Site 20
T176
T
I
K
G
D
T
D
T
A
K
T
S
D
D
I
Site 21
T179
G
D
T
D
T
A
K
T
S
D
D
I
S
L
S
Site 22
S180
D
T
D
T
A
K
T
S
D
D
I
S
L
S
L
Site 23
S184
A
K
T
S
D
D
I
S
L
S
L
G
Q
S
S
Site 24
S186
T
S
D
D
I
S
L
S
L
G
Q
S
S
S
L
Site 25
S190
I
S
L
S
L
G
Q
S
S
S
L
C
K
E
G
Site 26
S192
L
S
L
G
Q
S
S
S
L
C
K
E
G
S
E
Site 27
S198
S
S
L
C
K
E
G
S
E
E
Q
D
L
A
A
Site 28
S217
F
R
L
V
S
N
D
S
F
I
S
I
Q
P
S
Site 29
S220
V
S
N
D
S
F
I
S
I
Q
P
S
L
S
S
Site 30
S224
S
F
I
S
I
Q
P
S
L
S
S
C
G
Q
D
Site 31
S226
I
S
I
Q
P
S
L
S
S
C
G
Q
D
L
P
Site 32
S237
Q
D
L
P
R
D
F
S
D
K
V
N
L
P
S
Site 33
S256
H
H
V
D
Q
S
L
S
S
A
C
D
T
E
V
Site 34
S257
H
V
D
Q
S
L
S
S
A
C
D
T
E
V
A
Site 35
S271
A
S
L
V
P
L
H
S
H
S
Y
R
K
D
H
Site 36
S273
L
V
P
L
H
S
H
S
Y
R
K
D
H
R
P
Site 37
T286
R
P
R
G
V
P
R
T
S
S
S
A
V
A
F
Site 38
S287
P
R
G
V
P
R
T
S
S
S
A
V
A
F
P
Site 39
S288
R
G
V
P
R
T
S
S
S
A
V
A
F
P
D
Site 40
S289
G
V
P
R
T
S
S
S
A
V
A
F
P
D
T
Site 41
Y304
S
L
N
D
F
P
L
Y
Q
Q
R
R
G
L
D
Site 42
S314
R
R
G
L
D
P
V
S
E
L
E
S
S
K
P
Site 43
S318
D
P
V
S
E
L
E
S
S
K
P
L
S
G
S
Site 44
S319
P
V
S
E
L
E
S
S
K
P
L
S
G
S
K
Site 45
S323
L
E
S
S
K
P
L
S
G
S
K
E
S
L
V
Site 46
S325
S
S
K
P
L
S
G
S
K
E
S
L
V
E
N
Site 47
S328
P
L
S
G
S
K
E
S
L
V
E
N
S
G
L
Site 48
T349
A
G
D
L
K
I
N
T
S
Q
P
P
T
K
S
Site 49
S350
G
D
L
K
I
N
T
S
Q
P
P
T
K
S
G
Site 50
T354
I
N
T
S
Q
P
P
T
K
S
G
K
S
K
P
Site 51
S356
T
S
Q
P
P
T
K
S
G
K
S
K
P
L
K
Site 52
S359
P
P
T
K
S
G
K
S
K
P
L
K
A
E
K
Site 53
S367
K
P
L
K
A
E
K
S
M
D
S
L
R
S
L
Site 54
S370
K
A
E
K
S
M
D
S
L
R
S
L
S
T
R
Site 55
S373
K
S
M
D
S
L
R
S
L
S
T
R
S
S
G
Site 56
S375
M
D
S
L
R
S
L
S
T
R
S
S
G
S
T
Site 57
T376
D
S
L
R
S
L
S
T
R
S
S
G
S
T
E
Site 58
S378
L
R
S
L
S
T
R
S
S
G
S
T
E
S
Y
Site 59
S379
R
S
L
S
T
R
S
S
G
S
T
E
S
Y
C
Site 60
S381
L
S
T
R
S
S
G
S
T
E
S
Y
C
S
G
Site 61
T382
S
T
R
S
S
G
S
T
E
S
Y
C
S
G
T
Site 62
S384
R
S
S
G
S
T
E
S
Y
C
S
G
T
D
R
Site 63
Y385
S
S
G
S
T
E
S
Y
C
S
G
T
D
R
D
Site 64
S387
G
S
T
E
S
Y
C
S
G
T
D
R
D
T
N
Site 65
T389
T
E
S
Y
C
S
G
T
D
R
D
T
N
S
T
Site 66
T393
C
S
G
T
D
R
D
T
N
S
T
V
S
S
Y
Site 67
S395
G
T
D
R
D
T
N
S
T
V
S
S
Y
K
S
Site 68
T396
T
D
R
D
T
N
S
T
V
S
S
Y
K
S
E
Site 69
S398
R
D
T
N
S
T
V
S
S
Y
K
S
E
Q
T
Site 70
S399
D
T
N
S
T
V
S
S
Y
K
S
E
Q
T
S
Site 71
S402
S
T
V
S
S
Y
K
S
E
Q
T
S
S
T
H
Site 72
S406
S
Y
K
S
E
Q
T
S
S
T
H
I
E
S
I
Site 73
S407
Y
K
S
E
Q
T
S
S
T
H
I
E
S
I
L
Site 74
T408
K
S
E
Q
T
S
S
T
H
I
E
S
I
L
S
Site 75
S415
T
H
I
E
S
I
L
S
E
H
E
E
S
P
K
Site 76
S420
I
L
S
E
H
E
E
S
P
K
A
G
T
K
S
Site 77
S427
S
P
K
A
G
T
K
S
G
R
K
K
E
C
C
Site 78
S442
A
G
P
E
E
K
N
S
C
A
S
D
K
R
T
Site 79
S445
E
E
K
N
S
C
A
S
D
K
R
T
S
S
E
Site 80
T449
S
C
A
S
D
K
R
T
S
S
E
K
I
A
M
Site 81
S450
C
A
S
D
K
R
T
S
S
E
K
I
A
M
E
Site 82
S451
A
S
D
K
R
T
S
S
E
K
I
A
M
E
A
Site 83
S459
E
K
I
A
M
E
A
S
T
N
S
G
V
H
E
Site 84
T471
V
H
E
A
K
D
P
T
P
S
D
E
M
H
N
Site 85
S473
E
A
K
D
P
T
P
S
D
E
M
H
N
Q
R
Site 86
S483
M
H
N
Q
R
G
L
S
T
S
A
S
E
E
A
Site 87
S485
N
Q
R
G
L
S
T
S
A
S
E
E
A
N
K
Site 88
S487
R
G
L
S
T
S
A
S
E
E
A
N
K
N
P
Site 89
S501
P
H
A
N
E
F
T
S
Q
G
D
R
P
P
G
Site 90
T510
G
D
R
P
P
G
N
T
A
E
N
K
E
E
K
Site 91
S518
A
E
N
K
E
E
K
S
D
K
S
A
V
S
V
Site 92
S521
K
E
E
K
S
D
K
S
A
V
S
V
D
S
K
Site 93
S524
K
S
D
K
S
A
V
S
V
D
S
K
V
R
K
Site 94
S527
K
S
A
V
S
V
D
S
K
V
R
K
D
V
G
Site 95
S546
E
G
D
V
R
P
K
S
S
S
V
I
H
R
T
Site 96
S548
D
V
R
P
K
S
S
S
V
I
H
R
T
A
S
Site 97
T553
S
S
S
V
I
H
R
T
A
S
A
H
K
S
G
Site 98
S555
S
V
I
H
R
T
A
S
A
H
K
S
G
R
R
Site 99
S559
R
T
A
S
A
H
K
S
G
R
R
R
T
G
K
Site 100
T564
H
K
S
G
R
R
R
T
G
K
K
R
A
S
S
Site 101
S570
R
T
G
K
K
R
A
S
S
F
D
S
S
R
H
Site 102
S571
T
G
K
K
R
A
S
S
F
D
S
S
R
H
R
Site 103
S574
K
R
A
S
S
F
D
S
S
R
H
R
D
Y
V
Site 104
S575
R
A
S
S
F
D
S
S
R
H
R
D
Y
V
C
Site 105
Y580
D
S
S
R
H
R
D
Y
V
C
F
R
G
V
S
Site 106
S587
Y
V
C
F
R
G
V
S
G
T
K
P
H
S
A
Site 107
S593
V
S
G
T
K
P
H
S
A
I
F
C
H
D
E
Site 108
S602
I
F
C
H
D
E
D
S
S
D
Q
S
D
L
S
Site 109
S603
F
C
H
D
E
D
S
S
D
Q
S
D
L
S
R
Site 110
S606
D
E
D
S
S
D
Q
S
D
L
S
R
A
S
S
Site 111
S609
S
S
D
Q
S
D
L
S
R
A
S
S
V
Q
S
Site 112
S612
Q
S
D
L
S
R
A
S
S
V
Q
S
A
H
Q
Site 113
S613
S
D
L
S
R
A
S
S
V
Q
S
A
H
Q
F
Site 114
S616
S
R
A
S
S
V
Q
S
A
H
Q
F
S
S
D
Site 115
S621
V
Q
S
A
H
Q
F
S
S
D
S
S
S
S
T
Site 116
S622
Q
S
A
H
Q
F
S
S
D
S
S
S
S
T
T
Site 117
S624
A
H
Q
F
S
S
D
S
S
S
S
T
T
S
H
Site 118
S625
H
Q
F
S
S
D
S
S
S
S
T
T
S
H
S
Site 119
S626
Q
F
S
S
D
S
S
S
S
T
T
S
H
S
C
Site 120
S627
F
S
S
D
S
S
S
S
T
T
S
H
S
C
Q
Site 121
T628
S
S
D
S
S
S
S
T
T
S
H
S
C
Q
S
Site 122
T629
S
D
S
S
S
S
T
T
S
H
S
C
Q
S
P
Site 123
S630
D
S
S
S
S
T
T
S
H
S
C
Q
S
P
E
Site 124
S632
S
S
S
T
T
S
H
S
C
Q
S
P
E
G
R
Site 125
S635
T
T
S
H
S
C
Q
S
P
E
G
R
Y
S
A
Site 126
S641
Q
S
P
E
G
R
Y
S
A
L
K
T
K
H
T
Site 127
T645
G
R
Y
S
A
L
K
T
K
H
T
H
K
E
R
Site 128
T648
S
A
L
K
T
K
H
T
H
K
E
R
G
T
D
Site 129
T654
H
T
H
K
E
R
G
T
D
S
E
H
T
H
K
Site 130
S656
H
K
E
R
G
T
D
S
E
H
T
H
K
A
H
Site 131
T675
G
T
S
K
K
R
A
T
R
R
T
S
S
T
N
Site 132
T678
K
K
R
A
T
R
R
T
S
S
T
N
S
A
K
Site 133
S679
K
R
A
T
R
R
T
S
S
T
N
S
A
K
T
Site 134
S680
R
A
T
R
R
T
S
S
T
N
S
A
K
T
R
Site 135
T681
A
T
R
R
T
S
S
T
N
S
A
K
T
R
A
Site 136
S683
R
R
T
S
S
T
N
S
A
K
T
R
A
R
V
Site 137
T686
S
S
T
N
S
A
K
T
R
A
R
V
L
S
L
Site 138
S692
K
T
R
A
R
V
L
S
L
D
S
G
T
V
A
Site 139
S704
T
V
A
C
L
N
D
S
N
R
L
M
A
P
E
Site 140
S712
N
R
L
M
A
P
E
S
I
K
P
L
T
T
S
Site 141
T717
P
E
S
I
K
P
L
T
T
S
K
S
D
L
E
Site 142
S719
S
I
K
P
L
T
T
S
K
S
D
L
E
A
K
Site 143
S721
K
P
L
T
T
S
K
S
D
L
E
A
K
E
G
Site 144
S735
G
E
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V
Q
I
V
D
P
S
Q
I
L
E
G
I
N
Site 297
S2262
I
L
E
G
I
N
L
S
K
R
K
E
L
Q
W
Site 298
S2282
R
L
K
A
G
R
N
S
W
K
D
W
S
P
Q
Site 299
S2287
R
N
S
W
K
D
W
S
P
Q
E
G
M
E
G
Site 300
S2304
I
H
R
W
V
P
C
S
R
D
P
G
T
R
S
Site 301
T2309
P
C
S
R
D
P
G
T
R
S
H
I
D
K
A
Site 302
S2311
S
R
D
P
G
T
R
S
H
I
D
K
A
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation