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Updated November 2019
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Protein Info
Short Name:
TUBGCP6
Full Name:
Gamma-tubulin complex component 6
Alias:
DJ402G11.6; GCP6; GCP-6; KIAA1669; Tubulin, gamma complex associated protein 6
Type:
Cytoskeletal protein
Mass (Da):
200498
Number AA:
1819
UniProt ID:
Q96RT7
International Prot ID:
IPI00045491
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005829
GO:0008274
Uniprot
OncoNet
Molecular Function:
GO:0008017
PhosphoSite+
KinaseNET
Biological Process:
GO:0007020
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
K
T
H
L
G
Q
R
S
V
N
R
K
R
A
K
Site 2
S36
N
R
K
R
A
K
R
S
L
K
K
V
A
Y
N
Site 3
Y42
R
S
L
K
K
V
A
Y
N
A
L
F
T
N
L
Site 4
T54
T
N
L
F
Q
D
E
T
Q
Q
L
Q
P
D
M
Site 5
S62
Q
Q
L
Q
P
D
M
S
K
L
P
A
R
N
K
Site 6
Y132
V
L
P
R
K
R
D
Y
F
L
N
N
K
H
V
Site 7
S146
V
G
R
N
V
P
Y
S
G
Y
D
C
D
D
L
Site 8
Y148
R
N
V
P
Y
S
G
Y
D
C
D
D
L
S
V
Site 9
S162
V
F
E
M
D
V
Q
S
L
I
S
R
E
E
C
Site 10
T210
G
D
R
F
E
R
D
T
R
V
S
L
F
G
A
Site 11
Y224
A
L
V
H
S
R
T
Y
D
M
D
V
R
L
G
Site 12
S242
V
P
D
N
A
D
L
S
G
L
A
I
K
V
P
Site 13
S251
L
A
I
K
V
P
P
S
V
D
Q
W
E
D
E
Site 14
S262
W
E
D
E
G
F
Q
S
A
S
N
L
T
P
D
Site 15
T267
F
Q
S
A
S
N
L
T
P
D
S
Q
S
E
P
Site 16
S270
A
S
N
L
T
P
D
S
Q
S
E
P
S
V
T
Site 17
S272
N
L
T
P
D
S
Q
S
E
P
S
V
T
P
D
Site 18
S275
P
D
S
Q
S
E
P
S
V
T
P
D
V
D
L
Site 19
T277
S
Q
S
E
P
S
V
T
P
D
V
D
L
W
E
Site 20
T288
D
L
W
E
A
A
L
T
Y
E
A
S
K
R
R
Site 21
S292
A
A
L
T
Y
E
A
S
K
R
R
C
W
E
R
Site 22
Y311
P
G
H
R
E
E
P
Y
L
T
E
A
G
R
D
Site 23
T313
H
R
E
E
P
Y
L
T
E
A
G
R
D
A
F
Site 24
S386
V
K
R
G
V
H
V
S
G
A
S
P
E
S
I
Site 25
S392
V
S
G
A
S
P
E
S
I
S
S
L
L
S
E
Site 26
S395
A
S
P
E
S
I
S
S
L
L
S
E
V
A
E
Site 27
S398
E
S
I
S
S
L
L
S
E
V
A
E
Y
G
T
Site 28
Y407
V
A
E
Y
G
T
C
Y
T
R
L
S
H
F
S
Site 29
S411
G
T
C
Y
T
R
L
S
H
F
S
L
Q
P
V
Site 30
S414
Y
T
R
L
S
H
F
S
L
Q
P
V
L
D
S
Site 31
Y439
F
T
S
G
L
R
R
Y
L
Q
Y
Y
R
A
C
Site 32
Y442
G
L
R
R
Y
L
Q
Y
Y
R
A
C
V
L
S
Site 33
Y443
L
R
R
Y
L
Q
Y
Y
R
A
C
V
L
S
T
Site 34
Y518
H
N
C
S
N
E
H
Y
P
V
L
L
S
L
L
Site 35
Y532
L
K
T
S
C
E
P
Y
T
R
F
I
H
D
W
Site 36
Y541
R
F
I
H
D
W
V
Y
S
G
V
F
R
D
A
Site 37
Y560
M
I
Q
V
N
H
E
Y
L
S
F
R
D
K
L
Site 38
Y568
L
S
F
R
D
K
L
Y
W
T
H
G
Y
V
L
Site 39
Y573
K
L
Y
W
T
H
G
Y
V
L
I
S
K
E
V
Site 40
Y596
K
H
I
A
H
D
I
Y
V
C
G
K
T
I
N
Site 41
S629
P
R
I
S
V
I
F
S
L
E
E
L
K
E
I
Site 42
Y643
I
E
K
D
C
A
V
Y
V
G
R
M
E
R
V
Site 43
S654
M
E
R
V
A
R
H
S
S
V
S
K
E
E
K
Site 44
S655
E
R
V
A
R
H
S
S
V
S
K
E
E
K
E
Site 45
S657
V
A
R
H
S
S
V
S
K
E
E
K
E
L
R
Site 46
S681
A
H
A
R
E
A
A
S
R
V
L
S
A
L
S
Site 47
S685
E
A
A
S
R
V
L
S
A
L
S
D
R
Q
M
Site 48
S688
S
R
V
L
S
A
L
S
D
R
Q
M
S
E
R
Site 49
S693
A
L
S
D
R
Q
M
S
E
R
M
A
L
D
A
Site 50
S733
E
E
L
D
D
D
F
S
Y
A
R
E
L
R
D
Site 51
Y734
E
L
D
D
D
F
S
Y
A
R
E
L
R
D
R
Site 52
S747
D
R
E
R
R
L
K
S
L
E
E
E
L
E
R
Site 53
Y764
R
Q
A
L
V
D
H
Y
S
K
L
S
A
E
A
Site 54
S765
Q
A
L
V
D
H
Y
S
K
L
S
A
E
A
A
Site 55
S789
I
Q
R
H
R
L
E
S
A
R
L
R
F
L
L
Site 56
S824
E
P
P
D
V
L
L
S
V
H
P
Q
V
T
S
Site 57
S831
S
V
H
P
Q
V
T
S
P
G
P
E
H
P
E
Site 58
S845
E
G
G
Q
G
C
D
S
G
S
A
E
Q
H
S
Site 59
S847
G
Q
G
C
D
S
G
S
A
E
Q
H
S
P
A
Site 60
S852
S
G
S
A
E
Q
H
S
P
A
W
D
G
W
N
Site 61
T865
W
N
R
P
G
L
L
T
P
Q
P
L
K
P
L
Site 62
S891
A
E
G
A
R
P
F
S
D
S
L
S
I
G
D
Site 63
S932
I
N
L
D
L
P
P
S
A
P
G
E
A
P
A
Site 64
S942
G
E
A
P
A
A
A
S
T
Q
P
S
R
P
Q
Site 65
S946
A
A
A
S
T
Q
P
S
R
P
Q
E
Y
D
F
Site 66
S954
R
P
Q
E
Y
D
F
S
T
V
L
R
P
A
V
Site 67
T955
P
Q
E
Y
D
F
S
T
V
L
R
P
A
V
A
Site 68
T963
V
L
R
P
A
V
A
T
S
P
A
P
G
P
L
Site 69
S964
L
R
P
A
V
A
T
S
P
A
P
G
P
L
Q
Site 70
S976
P
L
Q
A
A
E
C
S
L
G
S
S
G
L
Q
Site 71
S980
A
E
C
S
L
G
S
S
G
L
Q
L
W
E
D
Site 72
S997
G
K
M
D
A
C
G
S
A
S
R
E
T
L
L
Site 73
T1002
C
G
S
A
S
R
E
T
L
L
P
S
H
P
P
Site 74
S1006
S
R
E
T
L
L
P
S
H
P
P
R
R
A
A
Site 75
S1019
A
A
L
E
E
G
S
S
Q
P
T
E
R
L
F
Site 76
T1022
E
E
G
S
S
Q
P
T
E
R
L
F
G
Q
V
Site 77
S1030
E
R
L
F
G
Q
V
S
G
G
G
L
P
T
G
Site 78
Y1039
G
G
L
P
T
G
D
Y
A
S
E
I
A
P
T
Site 79
S1041
L
P
T
G
D
Y
A
S
E
I
A
P
T
R
P
Site 80
T1046
Y
A
S
E
I
A
P
T
R
P
R
W
N
T
H
Site 81
T1052
P
T
R
P
R
W
N
T
H
G
H
V
S
D
A
Site 82
S1057
W
N
T
H
G
H
V
S
D
A
S
I
R
V
G
Site 83
S1060
H
G
H
V
S
D
A
S
I
R
V
G
E
N
V
Site 84
T1079
P
T
Q
P
R
W
N
T
H
G
H
V
S
N
A
Site 85
S1084
W
N
T
H
G
H
V
S
N
A
S
I
S
L
G
Site 86
S1087
H
G
H
V
S
N
A
S
I
S
L
G
E
S
V
Site 87
S1089
H
V
S
N
A
S
I
S
L
G
E
S
V
S
D
Site 88
S1095
I
S
L
G
E
S
V
S
D
V
A
P
T
R
P
Site 89
S1114
H
G
H
V
S
N
A
S
I
R
V
G
E
N
V
Site 90
T1133
P
T
R
P
R
W
N
T
H
G
H
V
S
N
A
Site 91
S1165
W
N
T
H
G
H
V
S
D
A
S
I
S
L
G
Site 92
S1168
H
G
H
V
S
D
A
S
I
S
L
G
E
S
V
Site 93
S1170
H
V
S
D
A
S
I
S
L
G
E
S
V
S
D
Site 94
S1176
I
S
L
G
E
S
V
S
D
M
A
P
A
R
P
Site 95
T1187
P
A
R
P
R
W
N
T
H
G
H
V
S
D
A
Site 96
S1203
I
S
L
G
E
S
V
S
D
M
A
P
T
R
P
Site 97
T1214
P
T
R
P
R
W
N
T
H
G
H
V
S
D
T
Site 98
T1221
T
H
G
H
V
S
D
T
S
I
R
V
G
E
N
Site 99
S1222
H
G
H
V
S
D
T
S
I
R
V
G
E
N
V
Site 100
S1237
S
D
V
A
P
I
R
S
R
C
N
T
H
G
H
Site 101
T1241
P
I
R
S
R
C
N
T
H
G
H
V
S
D
A
Site 102
S1246
C
N
T
H
G
H
V
S
D
A
S
I
S
L
G
Site 103
S1249
H
G
H
V
S
D
A
S
I
S
L
G
E
P
V
Site 104
S1251
H
V
S
D
A
S
I
S
L
G
E
P
V
S
D
Site 105
S1257
I
S
L
G
E
P
V
S
D
V
V
S
T
R
P
Site 106
S1261
E
P
V
S
D
V
V
S
T
R
P
R
W
N
T
Site 107
T1268
S
T
R
P
R
W
N
T
H
V
P
I
P
P
P
Site 108
S1283
H
M
V
L
G
A
L
S
P
E
A
E
P
N
T
Site 109
T1290
S
P
E
A
E
P
N
T
P
R
P
Q
Q
S
P
Site 110
S1296
N
T
P
R
P
Q
Q
S
P
P
G
H
T
S
Q
Site 111
S1302
Q
S
P
P
G
H
T
S
Q
S
A
L
S
L
G
Site 112
S1304
P
P
G
H
T
S
Q
S
A
L
S
L
G
A
Q
Site 113
S1307
H
T
S
Q
S
A
L
S
L
G
A
Q
S
T
V
Site 114
S1328
L
P
V
E
V
G
P
S
L
S
S
P
S
S
G
Site 115
S1330
V
E
V
G
P
S
L
S
S
P
S
S
G
C
G
Site 116
S1331
E
V
G
P
S
L
S
S
P
S
S
G
C
G
E
Site 117
S1334
P
S
L
S
S
P
S
S
G
C
G
E
G
S
I
Site 118
S1340
S
S
G
C
G
E
G
S
I
S
V
G
E
N
V
Site 119
S1342
G
C
G
E
G
S
I
S
V
G
E
N
V
S
D
Site 120
S1348
I
S
V
G
E
N
V
S
D
V
A
P
T
Q
P
Site 121
T1360
T
Q
P
W
W
P
N
T
P
G
D
S
V
S
E
Site 122
S1364
W
P
N
T
P
G
D
S
V
S
E
E
L
G
P
Site 123
S1366
N
T
P
G
D
S
V
S
E
E
L
G
P
G
R
Site 124
S1374
E
E
L
G
P
G
R
S
G
D
T
E
D
L
S
Site 125
T1377
G
P
G
R
S
G
D
T
E
D
L
S
P
N
W
Site 126
S1381
S
G
D
T
E
D
L
S
P
N
W
P
L
N
S
Site 127
S1388
S
P
N
W
P
L
N
S
Q
E
D
T
A
A
Q
Site 128
T1392
P
L
N
S
Q
E
D
T
A
A
Q
S
S
P
G
Site 129
S1397
E
D
T
A
A
Q
S
S
P
G
R
G
E
E
A
Site 130
S1407
R
G
E
E
A
E
A
S
A
A
E
A
Q
G
G
Site 131
Y1418
A
Q
G
G
E
Q
A
Y
L
A
G
L
A
G
Q
Site 132
Y1431
G
Q
Y
H
L
E
R
Y
P
D
S
Y
E
S
M
Site 133
S1434
H
L
E
R
Y
P
D
S
Y
E
S
M
S
E
P
Site 134
Y1435
L
E
R
Y
P
D
S
Y
E
S
M
S
E
P
P
Site 135
S1437
R
Y
P
D
S
Y
E
S
M
S
E
P
P
I
A
Site 136
S1439
P
D
S
Y
E
S
M
S
E
P
P
I
A
H
L
Site 137
Y1517
E
L
H
L
E
A
H
Y
E
A
L
R
H
F
L
Site 138
S1534
E
D
G
E
F
A
Q
S
L
S
D
L
L
F
E
Site 139
T1548
E
K
L
G
A
G
Q
T
P
G
E
L
L
N
P
Site 140
S1569
L
S
K
A
L
Q
C
S
L
H
G
D
T
P
H
Site 141
T1574
Q
C
S
L
H
G
D
T
P
H
A
S
N
L
S
Site 142
S1581
T
P
H
A
S
N
L
S
L
A
L
K
Y
L
P
Site 143
S1600
P
N
A
P
D
V
L
S
C
L
E
L
R
Y
K
Site 144
Y1606
L
S
C
L
E
L
R
Y
K
V
D
W
P
L
N
Site 145
S1655
L
K
R
T
A
L
L
S
H
M
A
G
S
V
Q
Site 146
T1702
E
F
R
A
R
L
A
T
V
G
D
L
E
E
I
Site 147
Y1716
I
Q
R
A
H
A
E
Y
L
H
K
A
V
F
R
Site 148
S1753
K
F
R
S
Q
L
I
S
Q
A
W
G
P
P
G
Site 149
Y1777
F
A
L
M
Q
Q
S
Y
N
T
F
K
Y
Y
S
Site 150
Y1782
Q
S
Y
N
T
F
K
Y
Y
S
H
F
L
F
K
Site 151
Y1799
T
K
L
V
N
R
G
Y
Q
P
H
L
E
D
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation