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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UIMC1
Full Name:
BRCA1-A complex subunit RAP80
Alias:
Nuclear zinc finger protein RAP80; RAP80; Receptor associated protein 80; Receptor-associated protein 80; Retinoid X receptor-interacting protein 110; RXINP; Ubiquitin interaction motif containing 1; Ubiquitin interaction motif-containing protein 1
Type:
Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Mass (Da):
79727
Number AA:
719
UniProt ID:
Q96RL1
International Prot ID:
IPI00396071
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070531
Uniprot
OncoNet
Molecular Function:
GO:0070530
GO:0042393
PhosphoSite+
KinaseNET
Biological Process:
GO:0031572
GO:0006302
GO:0070537
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
K
K
K
V
K
E
V
S
E
S
R
N
L
E
K
Site 2
T24
L
E
K
K
D
V
E
T
T
S
S
V
S
V
K
Site 3
S26
K
K
D
V
E
T
T
S
S
V
S
V
K
R
K
Site 4
S27
K
D
V
E
T
T
S
S
V
S
V
K
R
K
R
Site 5
S44
E
D
A
F
I
V
I
S
D
S
D
G
E
E
P
Site 6
S46
A
F
I
V
I
S
D
S
D
G
E
E
P
K
E
Site 7
T60
E
E
N
G
L
Q
K
T
K
T
K
Q
S
N
R
Site 8
T62
N
G
L
Q
K
T
K
T
K
Q
S
N
R
A
K
Site 9
S65
Q
K
T
K
T
K
Q
S
N
R
A
K
C
L
A
Site 10
S101
Q
E
A
R
E
V
N
S
Q
E
E
E
E
E
E
Site 11
S117
L
R
K
A
I
A
E
S
L
N
S
C
R
P
S
Site 12
S120
A
I
A
E
S
L
N
S
C
R
P
S
D
A
S
Site 13
S124
S
L
N
S
C
R
P
S
D
A
S
A
T
R
S
Site 14
S127
S
C
R
P
S
D
A
S
A
T
R
S
R
P
L
Site 15
T129
R
P
S
D
A
S
A
T
R
S
R
P
L
A
T
Site 16
S131
S
D
A
S
A
T
R
S
R
P
L
A
T
G
P
Site 17
T136
T
R
S
R
P
L
A
T
G
P
S
S
Q
S
H
Site 18
S139
R
P
L
A
T
G
P
S
S
Q
S
H
Q
E
K
Site 19
S140
P
L
A
T
G
P
S
S
Q
S
H
Q
E
K
T
Site 20
T147
S
Q
S
H
Q
E
K
T
T
D
S
G
L
T
E
Site 21
S168
P
P
S
L
F
K
G
S
H
I
S
Q
G
N
E
Site 22
T186
R
E
E
P
W
D
H
T
E
K
T
E
E
E
P
Site 23
T189
P
W
D
H
T
E
K
T
E
E
E
P
V
S
G
Site 24
S195
K
T
E
E
E
P
V
S
G
S
S
G
S
W
D
Site 25
S198
E
E
P
V
S
G
S
S
G
S
W
D
Q
S
S
Site 26
S200
P
V
S
G
S
S
G
S
W
D
Q
S
S
Q
P
Site 27
S204
S
S
G
S
W
D
Q
S
S
Q
P
V
F
E
N
Site 28
S205
S
G
S
W
D
Q
S
S
Q
P
V
F
E
N
V
Site 29
T221
V
K
S
F
D
R
C
T
G
H
S
A
E
H
T
Site 30
T228
T
G
H
S
A
E
H
T
Q
C
G
K
P
Q
E
Site 31
S236
Q
C
G
K
P
Q
E
S
T
G
R
G
S
A
F
Site 32
T237
C
G
K
P
Q
E
S
T
G
R
G
S
A
F
L
Site 33
S241
Q
E
S
T
G
R
G
S
A
F
L
K
A
V
Q
Site 34
S250
F
L
K
A
V
Q
G
S
G
D
T
S
R
H
C
Site 35
T253
A
V
Q
G
S
G
D
T
S
R
H
C
L
P
T
Site 36
S254
V
Q
G
S
G
D
T
S
R
H
C
L
P
T
L
Site 37
T260
T
S
R
H
C
L
P
T
L
A
D
A
K
G
L
Site 38
Y292
D
G
V
D
P
N
Q
Y
T
K
V
I
L
C
Q
Site 39
S306
Q
L
E
V
Y
Q
K
S
L
K
M
A
Q
R
Q
Site 40
S330
P
V
L
P
R
P
P
S
L
I
Q
N
E
C
G
Site 41
S343
C
G
Q
G
E
Q
A
S
E
K
N
E
C
I
S
Site 42
S350
S
E
K
N
E
C
I
S
E
D
M
G
D
E
D
Site 43
S364
D
K
E
E
R
Q
E
S
R
A
S
D
W
H
S
Site 44
S367
E
R
Q
E
S
R
A
S
D
W
H
S
K
T
K
Site 45
S371
S
R
A
S
D
W
H
S
K
T
K
D
F
Q
E
Site 46
T373
A
S
D
W
H
S
K
T
K
D
F
Q
E
S
S
Site 47
S379
K
T
K
D
F
Q
E
S
S
I
K
S
L
K
E
Site 48
S380
T
K
D
F
Q
E
S
S
I
K
S
L
K
E
K
Site 49
S383
F
Q
E
S
S
I
K
S
L
K
E
K
L
L
L
Site 50
T395
L
L
L
E
E
E
P
T
T
S
H
G
Q
S
S
Site 51
T396
L
L
E
E
E
P
T
T
S
H
G
Q
S
S
Q
Site 52
S397
L
E
E
E
P
T
T
S
H
G
Q
S
S
Q
G
Site 53
S401
P
T
T
S
H
G
Q
S
S
Q
G
I
V
E
E
Site 54
S402
T
T
S
H
G
Q
S
S
Q
G
I
V
E
E
T
Site 55
S410
Q
G
I
V
E
E
T
S
E
E
G
N
S
V
P
Site 56
S415
E
T
S
E
E
G
N
S
V
P
A
S
Q
S
V
Site 57
S419
E
G
N
S
V
P
A
S
Q
S
V
A
A
L
T
Site 58
S421
N
S
V
P
A
S
Q
S
V
A
A
L
T
S
K
Site 59
T443
E
S
S
A
E
E
I
T
V
C
P
E
T
Q
L
Site 60
T448
E
I
T
V
C
P
E
T
Q
L
S
S
S
E
T
Site 61
S451
V
C
P
E
T
Q
L
S
S
S
E
T
F
D
L
Site 62
S453
P
E
T
Q
L
S
S
S
E
T
F
D
L
E
R
Site 63
T455
T
Q
L
S
S
S
E
T
F
D
L
E
R
E
V
Site 64
S463
F
D
L
E
R
E
V
S
P
G
S
R
D
I
L
Site 65
S466
E
R
E
V
S
P
G
S
R
D
I
L
D
G
V
Site 66
S495
A
E
K
E
V
A
I
S
T
F
S
S
S
N
Q
Site 67
T496
E
K
E
V
A
I
S
T
F
S
S
S
N
Q
V
Site 68
Y523
K
I
E
R
H
A
M
Y
C
N
G
L
M
E
E
Site 69
T532
N
G
L
M
E
E
D
T
V
L
T
R
R
Q
K
Site 70
T543
R
R
Q
K
E
A
K
T
K
S
D
S
G
T
A
Site 71
S545
Q
K
E
A
K
T
K
S
D
S
G
T
A
A
Q
Site 72
T549
K
T
K
S
D
S
G
T
A
A
Q
T
S
L
D
Site 73
S554
S
G
T
A
A
Q
T
S
L
D
I
D
K
N
E
Site 74
Y564
I
D
K
N
E
K
C
Y
L
C
K
S
L
V
P
Site 75
Y575
S
L
V
P
F
R
E
Y
Q
C
H
V
D
S
C
Site 76
S597
Q
G
D
G
P
E
G
S
G
R
A
C
S
T
V
Site 77
S602
E
G
S
G
R
A
C
S
T
V
E
G
K
W
Q
Site 78
T603
G
S
G
R
A
C
S
T
V
E
G
K
W
Q
Q
Site 79
S621
N
P
K
E
K
G
H
S
E
G
R
L
L
S
F
Site 80
S627
H
S
E
G
R
L
L
S
F
L
E
Q
S
E
H
Site 81
S632
L
L
S
F
L
E
Q
S
E
H
K
T
S
D
A
Site 82
T636
L
E
Q
S
E
H
K
T
S
D
A
D
I
K
S
Site 83
S637
E
Q
S
E
H
K
T
S
D
A
D
I
K
S
S
Site 84
S643
T
S
D
A
D
I
K
S
S
E
T
G
A
F
R
Site 85
S644
S
D
A
D
I
K
S
S
E
T
G
A
F
R
V
Site 86
S653
T
G
A
F
R
V
P
S
P
G
M
E
E
A
G
Site 87
S662
G
M
E
E
A
G
C
S
R
E
M
Q
S
S
F
Site 88
S668
C
S
R
E
M
Q
S
S
F
T
R
R
D
L
N
Site 89
S677
T
R
R
D
L
N
E
S
P
V
K
S
F
V
S
Site 90
S681
L
N
E
S
P
V
K
S
F
V
S
I
S
E
A
Site 91
T700
V
D
F
K
K
Q
V
T
V
Q
P
G
S
R
T
Site 92
S705
Q
V
T
V
Q
P
G
S
R
T
R
T
K
A
G
Site 93
T709
Q
P
G
S
R
T
R
T
K
A
G
R
G
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation