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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCDH15
Full Name:
Protocadherin-15
Alias:
DFNB23; PCD15; protocadherin 15; protocadherin-15; USH1F
Type:
Adhesion
Mass (Da):
216070
Number AA:
UniProt ID:
Q96QU1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0005615
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0050957
GO:0007156
GO:0045494
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y579
E
M
I
V
G
R
T
Y
A
L
T
V
Q
A
A
Site 2
Y931
P
V
F
S
K
R
I
Y
K
G
M
V
A
P
D
Site 3
T1410
K
V
R
Q
A
E
C
T
K
T
A
R
I
Q
A
Site 4
T1412
R
Q
A
E
C
T
K
T
A
R
I
Q
A
A
L
Site 5
Y1448
P
P
P
G
A
H
L
Y
E
E
L
G
D
S
S
Site 6
Y1461
S
S
I
L
F
L
L
Y
H
F
Q
Q
S
R
G
Site 7
S1473
S
R
G
N
N
S
V
S
E
D
R
K
H
Q
Q
Site 8
S1486
Q
Q
V
V
M
P
F
S
S
N
T
I
E
A
H
Site 9
S1495
N
T
I
E
A
H
K
S
A
H
V
D
G
S
L
Site 10
S1501
K
S
A
H
V
D
G
S
L
K
S
N
K
L
K
Site 11
S1504
H
V
D
G
S
L
K
S
N
K
L
K
S
A
R
Site 12
S1509
L
K
S
N
K
L
K
S
A
R
K
F
T
F
L
Site 13
T1514
L
K
S
A
R
K
F
T
F
L
S
D
E
D
D
Site 14
S1517
A
R
K
F
T
F
L
S
D
E
D
D
L
S
A
Site 15
S1523
L
S
D
E
D
D
L
S
A
H
N
P
L
Y
K
Site 16
Y1529
L
S
A
H
N
P
L
Y
K
E
N
I
S
Q
V
Site 17
S1534
P
L
Y
K
E
N
I
S
Q
V
S
T
N
S
D
Site 18
T1538
E
N
I
S
Q
V
S
T
N
S
D
I
S
Q
R
Site 19
S1540
I
S
Q
V
S
T
N
S
D
I
S
Q
R
T
D
Site 20
S1543
V
S
T
N
S
D
I
S
Q
R
T
D
F
V
D
Site 21
S1553
T
D
F
V
D
P
F
S
P
K
I
Q
A
K
S
Site 22
S1560
S
P
K
I
Q
A
K
S
K
S
L
R
G
P
R
Site 23
S1562
K
I
Q
A
K
S
K
S
L
R
G
P
R
E
K
Site 24
S1575
E
K
I
Q
R
L
W
S
Q
S
V
S
L
P
R
Site 25
S1577
I
Q
R
L
W
S
Q
S
V
S
L
P
R
R
L
Site 26
S1579
R
L
W
S
Q
S
V
S
L
P
R
R
L
M
R
Site 27
T1612
Q
K
A
E
N
E
N
T
G
I
C
T
N
K
R
Site 28
S1621
I
C
T
N
K
R
G
S
S
N
P
L
L
T
T
Site 29
S1622
C
T
N
K
R
G
S
S
N
P
L
L
T
T
E
Site 30
T1634
T
T
E
E
A
N
L
T
E
K
E
E
I
R
Q
Site 31
T1650
E
T
L
M
I
E
G
T
E
Q
L
K
S
L
S
Site 32
S1655
E
G
T
E
Q
L
K
S
L
S
S
D
S
S
F
Site 33
S1657
T
E
Q
L
K
S
L
S
S
D
S
S
F
C
F
Site 34
S1658
E
Q
L
K
S
L
S
S
D
S
S
F
C
F
P
Site 35
S1660
L
K
S
L
S
S
D
S
S
F
C
F
P
R
P
Site 36
S1661
K
S
L
S
S
D
S
S
F
C
F
P
R
P
H
Site 37
S1672
P
R
P
H
F
S
F
S
T
L
P
T
V
S
R
Site 38
T1673
R
P
H
F
S
F
S
T
L
P
T
V
S
R
T
Site 39
S1678
F
S
T
L
P
T
V
S
R
T
V
E
L
K
S
Site 40
T1680
T
L
P
T
V
S
R
T
V
E
L
K
S
E
P
Site 41
S1685
S
R
T
V
E
L
K
S
E
P
N
V
I
S
S
Site 42
S1691
K
S
E
P
N
V
I
S
S
P
A
E
C
S
L
Site 43
S1692
S
E
P
N
V
I
S
S
P
A
E
C
S
L
E
Site 44
S1697
I
S
S
P
A
E
C
S
L
E
L
S
P
S
R
Site 45
S1703
C
S
L
E
L
S
P
S
R
P
C
V
L
H
S
Site 46
S1710
S
R
P
C
V
L
H
S
S
L
S
R
R
E
T
Site 47
S1711
R
P
C
V
L
H
S
S
L
S
R
R
E
T
P
Site 48
S1713
C
V
L
H
S
S
L
S
R
R
E
T
P
I
C
Site 49
T1717
S
S
L
S
R
R
E
T
P
I
C
M
L
P
I
Site 50
S1741
F
A
H
P
P
N
I
S
P
S
A
C
P
L
P
Site 51
S1743
H
P
P
N
I
S
P
S
A
C
P
L
P
P
P
Site 52
S1754
L
P
P
P
P
P
I
S
P
P
S
P
P
P
A
Site 53
S1757
P
P
P
I
S
P
P
S
P
P
P
A
P
A
P
Site 54
S1775
P
P
D
I
S
P
F
S
L
F
C
P
P
P
S
Site 55
S1785
C
P
P
P
S
P
P
S
I
P
L
P
L
P
P
Site 56
S1799
P
P
T
F
F
P
L
S
V
S
T
S
G
P
P
Site 57
S1801
T
F
F
P
L
S
V
S
T
S
G
P
P
T
P
Site 58
S1803
F
P
L
S
V
S
T
S
G
P
P
T
P
P
L
Site 59
T1807
V
S
T
S
G
P
P
T
P
P
L
L
P
P
F
Site 60
T1816
P
L
L
P
P
F
P
T
P
L
P
P
P
P
P
Site 61
S1824
P
L
P
P
P
P
P
S
I
P
C
P
P
P
P
Site 62
S1832
I
P
C
P
P
P
P
S
A
S
F
L
S
T
E
Site 63
S1860
M
P
A
E
K
I
K
S
S
M
T
Q
L
S
T
Site 64
S1866
K
S
S
M
T
Q
L
S
T
T
T
V
C
K
T
Site 65
T1869
M
T
Q
L
S
T
T
T
V
C
K
T
D
P
Q
Site 66
T1873
S
T
T
T
V
C
K
T
D
P
Q
R
E
P
K
Site 67
S1895
N
L
A
E
L
E
K
S
V
A
N
M
Y
S
Q
Site 68
S1901
K
S
V
A
N
M
Y
S
Q
I
E
K
N
Y
L
Site 69
Y1907
Y
S
Q
I
E
K
N
Y
L
R
T
N
V
S
E
Site 70
T1917
T
N
V
S
E
L
Q
T
M
C
P
S
E
V
T
Site 71
S1936
T
S
E
Q
N
K
G
S
L
N
N
I
V
E
G
Site 72
S1948
V
E
G
T
E
K
Q
S
H
S
Q
S
T
S
L
Site 73
S1950
G
T
E
K
Q
S
H
S
Q
S
T
S
L
_
_
Site 74
S1952
E
K
Q
S
H
S
Q
S
T
S
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation