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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NIBP
Full Name:
Trafficking protein particle complex subunit 9
Alias:
IBP; IKBKBBP; IKK2 binding protein; KIAA1882; NIK- and IKBKB-binding protein; NIK and IKK(beta) binding protein; T1; Trafficking protein particle complex 9; TRAPP 120 kDa subunit; TRS120; Tularik gene 1; Tularik gene 1 protein
Type:
Activator protein
Mass (Da):
128530
Number AA:
1148
UniProt ID:
Q96Q05
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005783
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y35
E
E
N
F
F
R
I
Y
K
R
I
C
S
V
S
Site 2
S40
R
I
Y
K
R
I
C
S
V
S
Q
I
S
V
R
Site 3
S42
Y
K
R
I
C
S
V
S
Q
I
S
V
R
D
S
Site 4
S45
I
C
S
V
S
Q
I
S
V
R
D
S
Q
R
V
Site 5
S49
S
Q
I
S
V
R
D
S
Q
R
V
L
Y
I
R
Site 6
Y54
R
D
S
Q
R
V
L
Y
I
R
Y
R
H
H
Y
Site 7
Y57
Q
R
V
L
Y
I
R
Y
R
H
H
Y
P
P
E
Site 8
T73
N
E
W
G
D
F
Q
T
H
R
K
V
V
G
L
Site 9
T95
S
A
K
D
W
P
Q
T
F
E
K
F
H
V
Q
Site 10
T109
Q
K
E
I
Y
G
S
T
L
Y
D
S
R
L
F
Site 11
T130
E
I
V
E
Q
P
R
T
D
V
A
F
Y
P
N
Site 12
Y135
P
R
T
D
V
A
F
Y
P
N
Y
E
D
C
Q
Site 13
Y138
D
V
A
F
Y
P
N
Y
E
D
C
Q
T
V
E
Site 14
T143
P
N
Y
E
D
C
Q
T
V
E
K
R
I
E
D
Site 15
T168
S
K
R
L
D
R
A
T
D
K
S
G
D
K
I
Site 16
S171
L
D
R
A
T
D
K
S
G
D
K
I
P
L
L
Site 17
T192
K
D
F
V
G
L
D
T
D
S
R
H
Y
K
K
Site 18
Y197
L
D
T
D
S
R
H
Y
K
K
R
C
Q
G
R
Site 19
Y258
S
A
S
V
I
Y
H
Y
P
G
G
T
G
G
K
Site 20
S266
P
G
G
T
G
G
K
S
G
A
R
R
F
Q
G
Site 21
S274
G
A
R
R
F
Q
G
S
T
L
P
A
E
A
A
Site 22
T275
A
R
R
F
Q
G
S
T
L
P
A
E
A
A
N
Site 23
T299
L
I
D
P
G
A
L
T
T
N
G
I
N
P
D
Site 24
T307
T
N
G
I
N
P
D
T
S
T
E
I
G
R
A
Site 25
S308
N
G
I
N
P
D
T
S
T
E
I
G
R
A
K
Site 26
T309
G
I
N
P
D
T
S
T
E
I
G
R
A
K
N
Site 27
S319
G
R
A
K
N
C
L
S
P
E
D
I
I
D
K
Site 28
Y327
P
E
D
I
I
D
K
Y
K
E
A
I
S
Y
Y
Site 29
S332
D
K
Y
K
E
A
I
S
Y
Y
S
K
Y
K
N
Site 30
Y333
K
Y
K
E
A
I
S
Y
Y
S
K
Y
K
N
A
Site 31
Y334
Y
K
E
A
I
S
Y
Y
S
K
Y
K
N
A
G
Site 32
Y337
A
I
S
Y
Y
S
K
Y
K
N
A
G
V
I
E
Site 33
S365
Q
K
R
S
M
E
A
S
E
F
L
Q
N
A
V
Site 34
Y373
E
F
L
Q
N
A
V
Y
I
N
L
R
Q
L
S
Site 35
S380
Y
I
N
L
R
Q
L
S
E
E
E
K
I
Q
R
Site 36
Y388
E
E
E
K
I
Q
R
Y
S
I
L
S
E
L
Y
Site 37
S389
E
E
K
I
Q
R
Y
S
I
L
S
E
L
Y
E
Site 38
Y429
E
P
G
W
R
A
C
Y
K
L
L
L
E
T
L
Site 39
S440
L
E
T
L
P
G
Y
S
L
S
L
D
P
K
D
Site 40
S442
T
L
P
G
Y
S
L
S
L
D
P
K
D
F
S
Site 41
S449
S
L
D
P
K
D
F
S
R
G
T
H
R
G
W
Site 42
T452
P
K
D
F
S
R
G
T
H
R
G
W
A
A
V
Site 43
Y469
R
L
L
H
E
L
V
Y
A
S
R
R
M
G
N
Site 44
S471
L
H
E
L
V
Y
A
S
R
R
M
G
N
P
A
Site 45
S496
Q
T
M
L
D
F
L
S
D
Q
E
K
K
D
V
Site 46
S506
E
K
K
D
V
A
Q
S
L
E
N
Y
T
S
K
Site 47
Y510
V
A
Q
S
L
E
N
Y
T
S
K
C
P
G
T
Site 48
S512
Q
S
L
E
N
Y
T
S
K
C
P
G
T
M
E
Site 49
T517
Y
T
S
K
C
P
G
T
M
E
P
I
A
L
P
Site 50
S551
K
L
L
N
L
P
A
S
L
R
P
H
K
M
K
Site 51
S559
L
R
P
H
K
M
K
S
L
L
G
Q
N
V
S
Site 52
S566
S
L
L
G
Q
N
V
S
T
K
S
P
F
I
Y
Site 53
T567
L
L
G
Q
N
V
S
T
K
S
P
F
I
Y
S
Site 54
S569
G
Q
N
V
S
T
K
S
P
F
I
Y
S
P
I
Site 55
Y573
S
T
K
S
P
F
I
Y
S
P
I
I
A
H
N
Site 56
S574
T
K
S
P
F
I
Y
S
P
I
I
A
H
N
R
Site 57
T656
G
V
P
Q
T
T
G
T
I
T
V
N
G
Y
H
Site 58
T658
P
Q
T
T
G
T
I
T
V
N
G
Y
H
T
T
Site 59
T683
D
N
L
P
G
I
K
T
S
G
S
T
V
E
V
Site 60
S700
A
L
P
R
L
Q
I
S
T
S
L
P
R
S
A
Site 61
T701
L
P
R
L
Q
I
S
T
S
L
P
R
S
A
H
Site 62
S702
P
R
L
Q
I
S
T
S
L
P
R
S
A
H
S
Site 63
S706
I
S
T
S
L
P
R
S
A
H
S
L
Q
P
S
Site 64
S709
S
L
P
R
S
A
H
S
L
Q
P
S
S
G
D
Site 65
S713
S
A
H
S
L
Q
P
S
S
G
D
E
I
S
T
Site 66
S714
A
H
S
L
Q
P
S
S
G
D
E
I
S
T
N
Site 67
S719
P
S
S
G
D
E
I
S
T
N
V
S
V
Q
L
Site 68
T720
S
S
G
D
E
I
S
T
N
V
S
V
Q
L
Y
Site 69
S723
D
E
I
S
T
N
V
S
V
Q
L
Y
N
G
E
Site 70
Y727
T
N
V
S
V
Q
L
Y
N
G
E
S
Q
Q
L
Site 71
S731
V
Q
L
Y
N
G
E
S
Q
Q
L
I
I
K
L
Site 72
S753
L
E
K
L
E
V
T
S
K
V
L
T
T
K
E
Site 73
T757
E
V
T
S
K
V
L
T
T
K
E
K
L
Y
G
Site 74
T758
V
T
S
K
V
L
T
T
K
E
K
L
Y
G
D
Site 75
Y763
L
T
T
K
E
K
L
Y
G
D
F
L
S
W
K
Site 76
S768
K
L
Y
G
D
F
L
S
W
K
L
E
E
T
L
Site 77
T774
L
S
W
K
L
E
E
T
L
A
Q
F
P
L
Q
Site 78
S809
E
N
L
L
Q
D
L
S
D
D
G
I
S
V
S
Site 79
S814
D
L
S
D
D
G
I
S
V
S
G
F
P
L
S
Site 80
S816
S
D
D
G
I
S
V
S
G
F
P
L
S
S
P
Site 81
S842
K
P
V
N
P
P
E
S
N
K
A
G
D
Y
S
Site 82
Y848
E
S
N
K
A
G
D
Y
S
H
V
K
T
L
E
Site 83
S849
S
N
K
A
G
D
Y
S
H
V
K
T
L
E
A
Site 84
T853
G
D
Y
S
H
V
K
T
L
E
A
V
L
N
F
Site 85
Y862
E
A
V
L
N
F
K
Y
S
G
G
P
G
H
T
Site 86
S863
A
V
L
N
F
K
Y
S
G
G
P
G
H
T
E
Site 87
Y872
G
P
G
H
T
E
G
Y
Y
R
N
L
S
L
G
Site 88
Y873
P
G
H
T
E
G
Y
Y
R
N
L
S
L
G
L
Site 89
S877
E
G
Y
Y
R
N
L
S
L
G
L
H
V
E
V
Site 90
T899
R
V
S
T
L
P
A
T
S
T
R
Q
C
H
L
Site 91
T919
N
S
T
E
H
E
L
T
V
S
T
R
S
S
E
Site 92
S921
T
E
H
E
L
T
V
S
T
R
S
S
E
A
L
Site 93
S949
V
D
K
F
N
F
E
S
F
P
E
S
P
G
E
Site 94
S953
N
F
E
S
F
P
E
S
P
G
E
K
G
Q
F
Site 95
S990
G
I
C
W
R
I
P
S
L
K
R
S
G
E
A
Site 96
S994
R
I
P
S
L
K
R
S
G
E
A
S
V
E
G
Site 97
S998
L
K
R
S
G
E
A
S
V
E
G
L
L
N
Q
Site 98
T1048
V
R
L
E
V
R
L
T
N
R
S
P
R
S
V
Site 99
S1051
N
F
E
S
F
P
E
S
P
G
E
K
G
Q
F
Site 100
S1054
L
T
N
R
S
P
R
S
V
G
P
F
A
L
T
Site 101
T1080
H
N
Y
D
L
H
D
T
V
S
F
V
G
S
S
Site 102
S1082
Y
D
L
H
D
T
V
S
F
V
G
S
S
T
F
Site 103
S1124
H
I
R
F
H
E
D
S
T
S
K
E
L
P
P
Site 104
S1126
R
F
H
E
D
S
T
S
K
E
L
P
P
S
W
Site 105
S1132
T
S
K
E
L
P
P
S
W
F
C
L
P
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation