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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MIA2
Full Name:
Melanoma inhibitory activity protein 2
Alias:
Type:
Mass (Da):
61684
Number AA:
541
UniProt ID:
Q96PC5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S45
E
A
L
I
N
R
V
S
A
M
R
D
Y
R
G
Site 2
Y50
R
V
S
A
M
R
D
Y
R
G
P
D
C
R
Y
Site 3
Y57
Y
R
G
P
D
C
R
Y
L
N
F
T
K
G
E
Site 4
T61
D
C
R
Y
L
N
F
T
K
G
E
E
I
S
V
Site 5
Y69
K
G
E
E
I
S
V
Y
V
K
L
A
G
E
R
Site 6
Y89
G
K
G
K
E
F
G
Y
F
P
R
D
A
V
Q
Site 7
S103
Q
I
E
E
V
F
I
S
E
E
I
Q
M
S
T
Site 8
S109
I
S
E
E
I
Q
M
S
T
K
E
S
D
F
L
Site 9
T124
C
L
L
G
V
S
Y
T
F
D
N
E
D
S
E
Site 10
S130
Y
T
F
D
N
E
D
S
E
L
N
G
D
Y
G
Site 11
Y136
D
S
E
L
N
G
D
Y
G
E
N
I
Y
P
Y
Site 12
Y141
G
D
Y
G
E
N
I
Y
P
Y
E
E
D
K
D
Site 13
Y143
Y
G
E
N
I
Y
P
Y
E
E
D
K
D
E
K
Site 14
S151
E
E
D
K
D
E
K
S
S
I
Y
E
S
D
F
Site 15
Y154
K
D
E
K
S
S
I
Y
E
S
D
F
Q
I
E
Site 16
S156
E
K
S
S
I
Y
E
S
D
F
Q
I
E
P
G
Site 17
Y165
F
Q
I
E
P
G
F
Y
A
T
Y
E
S
T
L
Site 18
Y168
E
P
G
F
Y
A
T
Y
E
S
T
L
F
E
D
Site 19
S188
E
A
P
E
D
I
G
S
T
S
E
S
K
D
W
Site 20
S190
P
E
D
I
G
S
T
S
E
S
K
D
W
E
E
Site 21
S192
D
I
G
S
T
S
E
S
K
D
W
E
E
V
V
Site 22
S216
P
E
V
H
V
P
P
S
S
A
V
S
G
V
K
Site 23
S217
E
V
H
V
P
P
S
S
A
V
S
G
V
K
E
Site 24
S220
V
P
P
S
S
A
V
S
G
V
K
E
W
F
G
Site 25
S240
A
E
E
K
A
F
E
S
V
I
E
P
V
Q
E
Site 26
S248
V
I
E
P
V
Q
E
S
S
F
R
S
R
K
I
Site 27
S249
I
E
P
V
Q
E
S
S
F
R
S
R
K
I
A
Site 28
S252
V
Q
E
S
S
F
R
S
R
K
I
A
V
E
D
Site 29
S279
Q
T
E
H
Q
Q
E
S
E
S
E
I
D
S
V
Site 30
S281
E
H
Q
Q
E
S
E
S
E
I
D
S
V
P
K
Site 31
S285
E
S
E
S
E
I
D
S
V
P
K
T
Q
S
E
Site 32
T289
E
I
D
S
V
P
K
T
Q
S
E
L
A
S
E
Site 33
S291
D
S
V
P
K
T
Q
S
E
L
A
S
E
S
E
Site 34
S295
K
T
Q
S
E
L
A
S
E
S
E
H
I
P
K
Site 35
S305
E
H
I
P
K
P
Q
S
T
G
W
F
G
G
G
Site 36
Y316
F
G
G
G
F
T
S
Y
L
G
F
G
D
E
D
Site 37
S333
L
E
L
I
A
E
E
S
N
P
P
L
Q
D
F
Site 38
S343
P
L
Q
D
F
P
N
S
I
S
S
D
K
E
A
Site 39
T364
I
L
T
E
K
K
D
T
I
T
N
D
S
L
S
Site 40
T366
T
E
K
K
D
T
I
T
N
D
S
L
S
L
K
Site 41
S369
K
D
T
I
T
N
D
S
L
S
L
K
P
S
W
Site 42
S371
T
I
T
N
D
S
L
S
L
K
P
S
W
F
D
Site 43
S375
D
S
L
S
L
K
P
S
W
F
D
F
G
F
A
Site 44
T415
D
E
H
E
H
P
L
T
S
E
L
D
P
E
K
Site 45
S444
Q
I
D
K
K
P
V
S
E
K
T
D
E
S
D
Site 46
T447
K
K
P
V
S
E
K
T
D
E
S
D
T
I
P
Site 47
S450
V
S
E
K
T
D
E
S
D
T
I
P
Y
L
K
Site 48
T452
E
K
T
D
E
S
D
T
I
P
Y
L
K
K
F
Site 49
Y455
D
E
S
D
T
I
P
Y
L
K
K
F
L
Y
N
Site 50
Y461
P
Y
L
K
K
F
L
Y
N
F
D
N
P
W
N
Site 51
T496
N
V
I
E
N
E
E
T
G
E
F
S
I
D
N
Site 52
Y504
G
E
F
S
I
D
N
Y
P
T
D
N
T
K
V
Site 53
S516
T
K
V
M
I
F
K
S
S
Y
S
L
S
G
W
Site 54
S517
K
V
M
I
F
K
S
S
Y
S
L
S
G
W
Y
Site 55
S519
M
I
F
K
S
S
Y
S
L
S
G
W
Y
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation