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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB12
Full Name:
Serpin B12
Alias:
Type:
Mass (Da):
46276
Number AA:
405
UniProt ID:
Q96P63
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
R
H
K
N
I
F
F
S
P
L
S
L
S
A
A
Site 2
S48
M
V
R
L
G
A
R
S
D
S
A
H
Q
I
D
Site 3
S50
R
L
G
A
R
S
D
S
A
H
Q
I
D
E
V
Site 4
S64
V
L
H
F
N
E
F
S
Q
N
E
S
K
E
P
Site 5
S68
N
E
F
S
Q
N
E
S
K
E
P
D
P
C
L
Site 6
S77
E
P
D
P
C
L
K
S
N
K
Q
K
A
G
S
Site 7
S84
S
N
K
Q
K
A
G
S
L
N
N
E
S
G
L
Site 8
S101
C
Y
F
G
Q
L
L
S
K
L
D
R
I
K
T
Site 9
T108
S
K
L
D
R
I
K
T
D
Y
T
L
S
I
A
Site 10
Y110
L
D
R
I
K
T
D
Y
T
L
S
I
A
N
R
Site 11
T111
D
R
I
K
T
D
Y
T
L
S
I
A
N
R
L
Site 12
S113
I
K
T
D
Y
T
L
S
I
A
N
R
L
Y
G
Site 13
Y119
L
S
I
A
N
R
L
Y
G
E
Q
E
F
P
I
Site 14
S175
G
K
I
K
E
L
F
S
K
D
A
I
N
A
E
Site 15
Y200
F
K
A
K
W
E
T
Y
F
D
H
E
N
T
V
Site 16
Y247
A
Q
I
L
E
M
R
Y
T
K
G
K
L
S
M
Site 17
T248
Q
I
L
E
M
R
Y
T
K
G
K
L
S
M
F
Site 18
S260
S
M
F
V
L
L
P
S
H
S
K
D
N
L
K
Site 19
S262
F
V
L
L
P
S
H
S
K
D
N
L
K
G
L
Site 20
T277
E
E
L
E
R
K
I
T
Y
E
K
M
V
A
W
Site 21
S286
E
K
M
V
A
W
S
S
S
E
N
M
S
E
E
Site 22
S287
K
M
V
A
W
S
S
S
E
N
M
S
E
E
S
Site 23
S291
W
S
S
S
E
N
M
S
E
E
S
V
V
L
S
Site 24
S294
S
E
N
M
S
E
E
S
V
V
L
S
F
P
R
Site 25
S298
S
E
E
S
V
V
L
S
F
P
R
F
T
L
E
Site 26
T303
V
L
S
F
P
R
F
T
L
E
D
S
Y
D
L
Site 27
S307
P
R
F
T
L
E
D
S
Y
D
L
N
S
I
L
Site 28
Y308
R
F
T
L
E
D
S
Y
D
L
N
S
I
L
Q
Site 29
T326
I
T
D
I
F
D
E
T
R
A
D
L
T
G
I
Site 30
T331
D
E
T
R
A
D
L
T
G
I
S
P
S
P
N
Site 31
S334
R
A
D
L
T
G
I
S
P
S
P
N
L
Y
L
Site 32
S336
D
L
T
G
I
S
P
S
P
N
L
Y
L
S
K
Site 33
Y340
I
S
P
S
P
N
L
Y
L
S
K
I
I
H
K
Site 34
S342
P
S
P
N
L
Y
L
S
K
I
I
H
K
T
F
Site 35
T348
L
S
K
I
I
H
K
T
F
V
E
V
D
E
N
Site 36
S368
A
A
T
G
A
V
V
S
E
R
S
L
R
S
W
Site 37
S371
G
A
V
V
S
E
R
S
L
R
S
W
V
E
F
Site 38
S374
V
S
E
R
S
L
R
S
W
V
E
F
N
A
N
Site 39
Y399
K
T
Q
T
I
L
F
Y
G
R
V
C
S
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation