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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDFY2
Full Name:
WD repeat and FYVE domain-containing protein 2
Alias:
WD40- and FYVE domain-containing protein 2;Zinc finger FYVE domain-containing protein 22
Type:
Mass (Da):
45136
Number AA:
400
UniProt ID:
Q96P53
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
E
I
Q
P
K
P
L
T
R
K
P
I
L
L
Q
Site 2
S23
L
L
Q
R
M
E
G
S
Q
E
V
V
N
M
A
Site 3
S41
P
K
E
E
G
V
I
S
V
S
E
D
R
T
V
Site 4
S43
E
E
G
V
I
S
V
S
E
D
R
T
V
R
V
Site 5
T47
I
S
V
S
E
D
R
T
V
R
V
W
L
K
R
Site 6
S56
R
V
W
L
K
R
D
S
G
Q
Y
W
P
S
V
Site 7
Y59
L
K
R
D
S
G
Q
Y
W
P
S
V
Y
H
A
Site 8
S75
P
S
P
C
S
C
M
S
F
N
P
E
T
R
R
Site 9
T80
C
M
S
F
N
P
E
T
R
R
L
S
I
G
L
Site 10
S84
N
P
E
T
R
R
L
S
I
G
L
D
N
G
T
Site 11
S93
G
L
D
N
G
T
I
S
E
F
I
L
S
E
D
Site 12
S98
T
I
S
E
F
I
L
S
E
D
Y
N
K
M
T
Site 13
Y101
E
F
I
L
S
E
D
Y
N
K
M
T
P
V
K
Site 14
T105
S
E
D
Y
N
K
M
T
P
V
K
N
Y
Q
A
Site 15
S131
L
E
L
E
W
V
L
S
T
G
Q
D
K
Q
F
Site 16
S143
K
Q
F
A
W
H
C
S
E
S
G
Q
R
L
G
Site 17
Y152
S
G
Q
R
L
G
G
Y
R
T
S
A
V
A
S
Site 18
T154
Q
R
L
G
G
Y
R
T
S
A
V
A
S
G
L
Site 19
S155
R
L
G
G
Y
R
T
S
A
V
A
S
G
L
Q
Site 20
S159
Y
R
T
S
A
V
A
S
G
L
Q
F
D
V
E
Site 21
T167
G
L
Q
F
D
V
E
T
R
H
V
F
I
G
D
Site 22
T180
G
D
H
S
G
Q
V
T
I
L
K
L
E
Q
E
Site 23
T194
E
N
C
T
L
V
T
T
F
R
G
H
T
G
G
Site 24
S216
P
V
Q
R
V
L
F
S
G
S
S
D
H
S
V
Site 25
S218
Q
R
V
L
F
S
G
S
S
D
H
S
V
I
M
Site 26
S222
F
S
G
S
S
D
H
S
V
I
M
W
D
I
G
Site 27
T234
D
I
G
G
R
K
G
T
A
I
E
L
Q
G
H
Site 28
S249
N
D
R
V
Q
A
L
S
Y
A
Q
H
T
R
Q
Site 29
S259
Q
H
T
R
Q
L
I
S
C
G
G
D
G
G
I
Site 30
T278
M
D
V
E
R
Q
E
T
P
E
W
L
D
S
D
Site 31
S284
E
T
P
E
W
L
D
S
D
S
C
Q
K
C
D
Site 32
S326
K
A
V
C
G
K
C
S
S
K
R
S
S
I
P
Site 33
S327
A
V
C
G
K
C
S
S
K
R
S
S
I
P
L
Site 34
S330
G
K
C
S
S
K
R
S
S
I
P
L
M
G
F
Site 35
S331
K
C
S
S
K
R
S
S
I
P
L
M
G
F
E
Site 36
T359
T
D
E
E
R
A
P
T
A
T
F
H
D
S
K
Site 37
T361
E
E
R
A
P
T
A
T
F
H
D
S
K
H
N
Site 38
T383
A
T
R
G
W
L
L
T
S
G
T
D
K
V
I
Site 39
S384
T
R
G
W
L
L
T
S
G
T
D
K
V
I
K
Site 40
T386
G
W
L
L
T
S
G
T
D
K
V
I
K
L
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation