KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CENTB5
Full Name:
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3
Alias:
CENB5; Centaurin, beta 5; Centaurin-beta 5; Cnt-b5
Type:
Uncharacterized protein
Mass (Da):
92495
Number AA:
834
UniProt ID:
Q96P50
International Prot ID:
IPI00465167
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008060
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0032312
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
F
E
E
C
V
K
D
S
P
R
F
R
A
T
I
Site 2
T18
D
S
P
R
F
R
A
T
I
D
E
V
E
T
D
Site 3
S52
E
A
G
K
A
Y
V
S
T
S
R
L
F
V
S
Site 4
S59
S
T
S
R
L
F
V
S
G
V
R
D
L
S
Q
Site 5
S65
V
S
G
V
R
D
L
S
Q
Q
C
Q
G
D
T
Site 6
T72
S
Q
Q
C
Q
G
D
T
V
I
S
E
C
L
Q
Site 7
S84
C
L
Q
R
F
A
D
S
L
Q
E
V
V
N
Y
Site 8
S102
L
F
D
Q
A
Q
R
S
V
R
Q
Q
L
Q
S
Site 9
S109
S
V
R
Q
Q
L
Q
S
F
V
K
E
D
V
R
Site 10
T121
D
V
R
K
F
K
E
T
K
K
Q
F
D
K
V
Site 11
S135
V
R
E
D
L
E
L
S
L
V
R
N
A
Q
A
Site 12
T158
E
E
A
T
G
A
L
T
L
T
R
K
C
F
R
Site 13
S192
E
I
L
D
S
M
L
S
F
M
H
A
Q
S
S
Site 14
S199
S
F
M
H
A
Q
S
S
F
F
Q
Q
G
Y
S
Site 15
S206
S
F
F
Q
Q
G
Y
S
L
L
H
Q
L
D
P
Site 16
Y214
L
L
H
Q
L
D
P
Y
M
K
K
L
A
A
E
Site 17
S229
L
D
Q
L
V
I
D
S
A
V
E
K
R
E
M
Site 18
S253
R
T
L
L
Q
D
F
S
Y
D
E
S
K
V
E
Site 19
Y254
T
L
L
Q
D
F
S
Y
D
E
S
K
V
E
F
Site 20
S257
Q
D
F
S
Y
D
E
S
K
V
E
F
D
V
D
Site 21
S267
E
F
D
V
D
A
P
S
G
V
V
M
E
G
Y
Site 22
Y274
S
G
V
V
M
E
G
Y
L
F
K
R
A
S
N
Site 23
Y300
I
Q
N
S
Q
L
V
Y
Q
K
K
L
K
D
A
Site 24
T309
K
K
L
K
D
A
L
T
V
V
V
D
D
L
R
Site 25
S319
V
D
D
L
R
L
C
S
V
K
P
C
E
D
I
Site 26
S340
E
V
L
S
P
T
K
S
C
M
L
Q
A
D
S
Site 27
S364
A
V
Q
A
S
I
A
S
A
Y
R
E
S
P
D
Site 28
S369
I
A
S
A
Y
R
E
S
P
D
S
C
Y
S
E
Site 29
S372
A
Y
R
E
S
P
D
S
C
Y
S
E
R
L
D
Site 30
Y374
R
E
S
P
D
S
C
Y
S
E
R
L
D
R
T
Site 31
T381
Y
S
E
R
L
D
R
T
A
S
P
S
T
S
S
Site 32
S383
E
R
L
D
R
T
A
S
P
S
T
S
S
I
D
Site 33
S385
L
D
R
T
A
S
P
S
T
S
S
I
D
S
A
Site 34
T386
D
R
T
A
S
P
S
T
S
S
I
D
S
A
T
Site 35
S387
R
T
A
S
P
S
T
S
S
I
D
S
A
T
D
Site 36
S388
T
A
S
P
S
T
S
S
I
D
S
A
T
D
T
Site 37
S391
P
S
T
S
S
I
D
S
A
T
D
T
R
E
R
Site 38
T393
T
S
S
I
D
S
A
T
D
T
R
E
R
G
V
Site 39
T395
S
I
D
S
A
T
D
T
R
E
R
G
V
K
G
Site 40
S411
S
V
L
Q
R
V
Q
S
V
A
G
N
S
Q
C
Site 41
S416
V
Q
S
V
A
G
N
S
Q
C
G
D
C
G
Q
Site 42
S447
E
C
S
G
I
H
R
S
L
G
V
H
C
S
K
Site 43
S453
R
S
L
G
V
H
C
S
K
V
R
S
L
T
L
Site 44
S457
V
H
C
S
K
V
R
S
L
T
L
D
S
W
E
Site 45
T459
C
S
K
V
R
S
L
T
L
D
S
W
E
P
E
Site 46
S462
V
R
S
L
T
L
D
S
W
E
P
E
L
L
K
Site 47
Y483
N
S
A
V
N
Q
I
Y
E
A
Q
C
E
G
A
Site 48
S492
A
Q
C
E
G
A
G
S
R
K
P
T
A
S
S
Site 49
T496
G
A
G
S
R
K
P
T
A
S
S
S
R
Q
D
Site 50
S498
G
S
R
K
P
T
A
S
S
S
R
Q
D
K
E
Site 51
S499
S
R
K
P
T
A
S
S
S
R
Q
D
K
E
A
Site 52
S500
R
K
P
T
A
S
S
S
R
Q
D
K
E
A
W
Site 53
Y512
E
A
W
I
K
D
K
Y
V
E
K
K
F
L
R
Site 54
S543
Q
K
C
L
R
P
H
S
S
P
R
A
P
T
A
Site 55
S544
K
C
L
R
P
H
S
S
P
R
A
P
T
A
R
Site 56
T549
H
S
S
P
R
A
P
T
A
R
R
K
V
R
L
Site 57
T571
A
A
L
S
S
V
G
T
L
D
R
K
F
R
R
Site 58
S580
D
R
K
F
R
R
D
S
L
F
C
P
D
E
L
Site 59
S589
F
C
P
D
E
L
D
S
L
F
S
Y
F
D
A
Site 60
S592
D
E
L
D
S
L
F
S
Y
F
D
A
G
A
A
Site 61
S605
A
A
G
A
G
P
R
S
L
S
S
D
S
G
L
Site 62
S607
G
A
G
P
R
S
L
S
S
D
S
G
L
G
G
Site 63
S608
A
G
P
R
S
L
S
S
D
S
G
L
G
G
S
Site 64
S610
P
R
S
L
S
S
D
S
G
L
G
G
S
S
D
Site 65
S615
S
D
S
G
L
G
G
S
S
D
G
S
S
D
V
Site 66
S616
D
S
G
L
G
G
S
S
D
G
S
S
D
V
L
Site 67
S620
G
G
S
S
D
G
S
S
D
V
L
A
F
G
S
Site 68
S633
G
S
G
S
V
V
D
S
V
T
E
E
E
G
A
Site 69
T635
G
S
V
V
D
S
V
T
E
E
E
G
A
E
S
Site 70
S642
T
E
E
E
G
A
E
S
E
E
S
S
G
E
A
Site 71
S645
E
G
A
E
S
E
E
S
S
G
E
A
D
G
D
Site 72
S646
G
A
E
S
E
E
S
S
G
E
A
D
G
D
T
Site 73
T653
S
G
E
A
D
G
D
T
E
A
E
A
W
G
L
Site 74
T705
D
A
E
D
E
G
K
T
P
L
V
Q
A
V
L
Site 75
S734
A
D
V
N
Q
R
D
S
R
G
R
A
P
L
H
Site 76
T744
R
A
P
L
H
H
A
T
L
L
G
R
T
G
Q
Site 77
S813
P
P
G
A
L
A
G
S
P
T
E
L
Q
F
R
Site 78
T815
G
A
L
A
G
S
P
T
E
L
Q
F
R
R
C
Site 79
S828
R
C
I
Q
E
F
I
S
L
H
L
E
E
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation