PhosphoNET

           
Protein Info 
   
Short Name:  CIAS1
Full Name:  NACHT, LRR and PYD domains-containing protein 3
Alias:  AGTAVPRL; AII; AII/AVP; AII/AVP receptor-like; Angiotensin/vasopressin receptor AII/AVP-like; AVP; C1orf7; CLR1.1; Cold autoinflammatory syndrome 1; Cryopyrin; FCAS; FCU; Muckle-Wells syndrome; MWS; NACHT, LRR and PYD containing protein 3; NALP3; NLR family, pyrin domain containing 3; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; PYPAF1; PYRIN-containing APAF1-like protein 1
Type:  Inhibitor protein
Mass (Da):  117913
Number AA:  1034
UniProt ID:  Q96P20
International Prot ID:  IPI00374129
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0042834  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0009595  GO:0006917  GO:0006954 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S161ARLGESVSLNKRYTR
Site 2T193LAIGKTKTCESPVSP
Site 3S710QCVLPSSSHAACSHG
Site 4S740SVLSTSQSLTELDLS
Site 5S968TLLTSSQSLRKLSLG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation