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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
P15RS
Full Name:
Regulation of nuclear pre-mRNA domain-containing protein 1A
Alias:
p15INK4B-related protein
Type:
Mass (Da):
35702
Number AA:
312
UniProt ID:
Q96P16
International Prot ID:
IPI00102425
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
A
F
S
E
A
A
L
Site 2
S5
_
_
_
M
S
A
F
S
E
A
A
L
E
K
K
Site 3
S14
A
A
L
E
K
K
L
S
E
L
S
N
S
Q
Q
Site 4
S17
E
K
K
L
S
E
L
S
N
S
Q
Q
S
V
Q
Site 5
S19
K
L
S
E
L
S
N
S
Q
Q
S
V
Q
T
L
Site 6
S22
E
L
S
N
S
Q
Q
S
V
Q
T
L
S
L
W
Site 7
S27
Q
Q
S
V
Q
T
L
S
L
W
L
I
H
H
R
Site 8
S37
L
I
H
H
R
K
H
S
R
P
I
V
T
V
W
Site 9
T42
K
H
S
R
P
I
V
T
V
W
E
R
E
L
R
Site 10
T58
A
K
P
N
R
K
L
T
F
L
Y
L
A
N
D
Site 11
Y61
N
R
K
L
T
F
L
Y
L
A
N
D
V
I
Q
Site 12
S70
A
N
D
V
I
Q
N
S
K
R
K
G
P
E
F
Site 13
S93
V
E
A
F
K
H
V
S
S
E
T
D
E
S
C
Site 14
S94
E
A
F
K
H
V
S
S
E
T
D
E
S
C
K
Site 15
T96
F
K
H
V
S
S
E
T
D
E
S
C
K
K
H
Site 16
S99
V
S
S
E
T
D
E
S
C
K
K
H
L
G
R
Site 17
S109
K
H
L
G
R
V
L
S
I
W
E
E
R
S
V
Site 18
S115
L
S
I
W
E
E
R
S
V
Y
E
N
D
V
L
Site 19
Y117
I
W
E
E
R
S
V
Y
E
N
D
V
L
E
Q
Site 20
Y130
E
Q
L
K
Q
A
L
Y
G
D
K
K
P
R
K
Site 21
T139
D
K
K
P
R
K
R
T
Y
E
Q
I
K
V
D
Site 22
Y140
K
K
P
R
K
R
T
Y
E
Q
I
K
V
D
E
Site 23
S152
V
D
E
N
E
N
C
S
S
L
G
S
P
S
E
Site 24
S153
D
E
N
E
N
C
S
S
L
G
S
P
S
E
P
Site 25
S156
E
N
C
S
S
L
G
S
P
S
E
P
P
Q
T
Site 26
S158
C
S
S
L
G
S
P
S
E
P
P
Q
T
L
D
Site 27
T163
S
P
S
E
P
P
Q
T
L
D
L
V
R
A
L
Site 28
S178
Q
D
L
E
N
A
A
S
G
D
A
A
V
H
Q
Site 29
S189
A
V
H
Q
R
I
A
S
L
P
V
E
V
Q
E
Site 30
S198
P
V
E
V
Q
E
V
S
L
L
D
K
I
T
D
Site 31
T204
V
S
L
L
D
K
I
T
D
K
E
S
G
E
R
Site 32
S208
D
K
I
T
D
K
E
S
G
E
R
L
S
K
M
Site 33
S213
K
E
S
G
E
R
L
S
K
M
V
E
D
A
C
Site 34
Y265
K
E
H
K
L
E
E
Y
K
R
K
L
A
R
V
Site 35
S273
K
R
K
L
A
R
V
S
L
V
R
K
E
L
R
Site 36
S281
L
V
R
K
E
L
R
S
R
I
Q
S
L
P
D
Site 37
S285
E
L
R
S
R
I
Q
S
L
P
D
L
S
R
L
Site 38
S290
I
Q
S
L
P
D
L
S
R
L
P
N
V
T
G
Site 39
T296
L
S
R
L
P
N
V
T
G
S
H
M
H
L
P
Site 40
Y309
L
P
F
A
G
D
I
Y
S
E
D
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation