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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DACH2
Full Name:
Dachshund homolog 2
Alias:
Type:
Mass (Da):
65323
Number AA:
599
UniProt ID:
Q96NX9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
L
F
R
A
E
P
L
Y
S
T
P
R
E
P
P
Site 2
S30
F
R
A
E
P
L
Y
S
T
P
R
E
P
P
R
Site 3
T31
R
A
E
P
L
Y
S
T
P
R
E
P
P
R
L
Site 4
T39
P
R
E
P
P
R
L
T
P
N
M
I
N
S
F
Site 5
S52
S
F
V
V
N
N
H
S
N
S
A
G
G
G
G
Site 6
S54
V
V
N
N
H
S
N
S
A
G
G
G
G
R
G
Site 7
T63
G
G
G
G
R
G
N
T
N
T
N
E
C
R
M
Site 8
T65
G
G
R
G
N
T
N
T
N
E
C
R
M
V
D
Site 9
T108
H
L
V
G
G
L
H
T
V
Y
T
K
L
K
R
Site 10
Y110
V
G
G
L
H
T
V
Y
T
K
L
K
R
L
D
Site 11
T111
G
G
L
H
T
V
Y
T
K
L
K
R
L
D
I
Site 12
T148
V
N
R
C
K
L
I
T
R
K
D
F
E
T
L
Site 13
T154
I
T
R
K
D
F
E
T
L
F
T
D
C
T
N
Site 14
T157
K
D
F
E
T
L
F
T
D
C
T
N
A
R
R
Site 15
T160
E
T
L
F
T
D
C
T
N
A
R
R
K
R
Q
Site 16
T169
A
R
R
K
R
Q
M
T
R
K
Q
A
V
N
S
Site 17
S176
T
R
K
Q
A
V
N
S
S
R
P
G
R
P
P
Site 18
S177
R
K
Q
A
V
N
S
S
R
P
G
R
P
P
K
Site 19
S186
P
G
R
P
P
K
R
S
L
G
V
L
Q
E
N
Site 20
T236
M
K
L
M
A
M
N
T
L
Q
G
N
G
S
Q
Site 21
S242
N
T
L
Q
G
N
G
S
Q
N
G
T
E
S
E
Site 22
T246
G
N
G
S
Q
N
G
T
E
S
E
P
D
D
L
Site 23
S248
G
S
Q
N
G
T
E
S
E
P
D
D
L
N
S
Site 24
S255
S
E
P
D
D
L
N
S
N
T
G
G
S
E
S
Site 25
S260
L
N
S
N
T
G
G
S
E
S
S
W
D
K
D
Site 26
S262
S
N
T
G
G
S
E
S
S
W
D
K
D
K
M
Site 27
S271
W
D
K
D
K
M
Q
S
P
F
A
A
P
G
P
Site 28
T298
P
G
I
G
G
A
P
T
L
N
P
L
Q
Q
N
Site 29
T309
L
Q
Q
N
H
L
L
T
N
R
L
D
L
P
F
Site 30
S357
A
A
A
A
Q
I
H
S
P
L
S
R
A
G
T
Site 31
T364
S
P
L
S
R
A
G
T
S
V
I
K
E
R
I
Site 32
S374
I
K
E
R
I
P
E
S
P
S
P
A
P
S
L
Site 33
S376
E
R
I
P
E
S
P
S
P
A
P
S
L
E
E
Site 34
S380
E
S
P
S
P
A
P
S
L
E
E
N
H
R
P
Site 35
S389
E
E
N
H
R
P
G
S
Q
T
S
S
H
T
S
Site 36
T391
N
H
R
P
G
S
Q
T
S
S
H
T
S
S
S
Site 37
S392
H
R
P
G
S
Q
T
S
S
H
T
S
S
S
V
Site 38
S393
R
P
G
S
Q
T
S
S
H
T
S
S
S
V
S
Site 39
T395
G
S
Q
T
S
S
H
T
S
S
S
V
S
S
S
Site 40
S396
S
Q
T
S
S
H
T
S
S
S
V
S
S
S
P
Site 41
S397
Q
T
S
S
H
T
S
S
S
V
S
S
S
P
S
Site 42
S398
T
S
S
H
T
S
S
S
V
S
S
S
P
S
Q
Site 43
S400
S
H
T
S
S
S
V
S
S
S
P
S
Q
M
D
Site 44
S401
H
T
S
S
S
V
S
S
S
P
S
Q
M
D
H
Site 45
S402
T
S
S
S
V
S
S
S
P
S
Q
M
D
H
H
Site 46
S404
S
S
V
S
S
S
P
S
Q
M
D
H
H
L
E
Site 47
T433
P
L
D
K
I
Q
L
T
P
G
Q
A
L
P
A
Site 48
T457
D
S
L
S
S
V
E
T
L
L
T
N
I
Q
G
Site 49
Y492
K
E
L
R
L
E
L
Y
R
E
R
E
I
R
E
Site 50
T514
V
E
L
Q
S
R
T
T
M
Q
K
R
L
K
K
Site 51
T525
R
L
K
K
E
K
K
T
K
R
K
L
Q
E
A
Site 52
S537
Q
E
A
L
E
F
E
S
K
R
R
E
Q
V
E
Site 53
T551
E
Q
A
L
K
Q
A
T
T
S
D
S
G
L
R
Site 54
S553
A
L
K
Q
A
T
T
S
D
S
G
L
R
M
L
Site 55
S555
K
Q
A
T
T
S
D
S
G
L
R
M
L
K
D
Site 56
T575
I
E
I
E
N
N
G
T
P
H
D
S
A
A
M
Site 57
S579
N
N
G
T
P
H
D
S
A
A
M
Q
G
G
N
Site 58
Y587
A
A
M
Q
G
G
N
Y
Y
C
L
E
M
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation