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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF583
Full Name:
Zinc finger protein 583
Alias:
Zinc finger protein L3-5
Type:
Mass (Da):
66033
Number AA:
569
UniProt ID:
Q96ND8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y31
N
P
A
Q
R
N
L
Y
R
K
V
M
L
E
N
Site 2
Y39
R
K
V
M
L
E
N
Y
R
S
L
V
S
L
G
Site 3
S44
E
N
Y
R
S
L
V
S
L
G
V
S
V
S
K
Site 4
Y81
G
P
C
P
D
W
E
Y
V
F
K
N
S
E
F
Site 5
S90
F
K
N
S
E
F
S
S
K
Q
E
T
Y
E
E
Site 6
T94
E
F
S
S
K
Q
E
T
Y
E
E
S
S
K
V
Site 7
Y95
F
S
S
K
Q
E
T
Y
E
E
S
S
K
V
V
Site 8
T103
E
E
S
S
K
V
V
T
V
G
A
R
H
L
S
Site 9
S110
T
V
G
A
R
H
L
S
Y
S
L
D
Y
P
S
Site 10
Y111
V
G
A
R
H
L
S
Y
S
L
D
Y
P
S
L
Site 11
S112
G
A
R
H
L
S
Y
S
L
D
Y
P
S
L
R
Site 12
Y115
H
L
S
Y
S
L
D
Y
P
S
L
R
E
D
C
Site 13
S117
S
Y
S
L
D
Y
P
S
L
R
E
D
C
Q
S
Site 14
Y128
D
C
Q
S
E
D
W
Y
K
N
Q
L
G
S
Q
Site 15
S134
W
Y
K
N
Q
L
G
S
Q
E
V
H
L
S
Q
Site 16
S140
G
S
Q
E
V
H
L
S
Q
L
I
I
T
H
K
Site 17
Y158
P
E
V
Q
N
K
E
Y
N
K
S
W
Q
T
F
Site 18
S176
T
I
F
D
I
Q
Q
S
F
P
T
K
E
K
A
Site 19
S192
K
H
E
P
Q
K
K
S
Y
R
K
K
S
V
E
Site 20
S197
K
K
S
Y
R
K
K
S
V
E
M
K
H
R
K
Site 21
Y206
E
M
K
H
R
K
V
Y
V
E
K
K
L
L
K
Site 22
S226
K
V
F
N
Q
S
S
S
L
T
L
H
Q
R
I
Site 23
T228
F
N
Q
S
S
S
L
T
L
H
Q
R
I
H
T
Site 24
T235
T
L
H
Q
R
I
H
T
G
E
K
P
Y
A
C
Site 25
Y240
I
H
T
G
E
K
P
Y
A
C
V
E
C
G
K
Site 26
S250
V
E
C
G
K
T
F
S
Q
S
A
N
L
A
Q
Site 27
T263
A
Q
H
K
R
I
H
T
G
E
K
P
Y
E
C
Site 28
Y268
I
H
T
G
E
K
P
Y
E
C
K
E
C
R
K
Site 29
S278
K
E
C
R
K
A
F
S
Q
N
A
H
L
A
Q
Site 30
T291
A
Q
H
Q
R
V
H
T
G
E
K
P
Y
Q
C
Site 31
Y296
V
H
T
G
E
K
P
Y
Q
C
K
E
C
K
K
Site 32
S306
K
E
C
K
K
A
F
S
Q
I
A
H
L
T
Q
Site 33
T319
T
Q
H
Q
R
V
H
T
G
E
R
P
F
E
C
Site 34
S337
G
K
A
F
S
N
G
S
F
L
A
Q
H
Q
R
Site 35
T347
A
Q
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 36
Y352
I
H
T
G
E
K
P
Y
V
C
N
V
C
G
K
Site 37
Y366
K
A
F
S
H
R
G
Y
L
I
V
H
Q
R
I
Site 38
T375
I
V
H
Q
R
I
H
T
G
E
R
P
Y
E
C
Site 39
Y380
I
H
T
G
E
R
P
Y
E
C
K
E
C
R
K
Site 40
S390
K
E
C
R
K
A
F
S
Q
Y
A
H
L
A
Q
Site 41
T403
A
Q
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 42
Y408
V
H
T
G
E
K
P
Y
E
C
K
V
C
R
K
Site 43
S418
K
V
C
R
K
A
F
S
Q
I
A
Y
L
D
Q
Site 44
Y422
K
A
F
S
Q
I
A
Y
L
D
Q
H
Q
R
V
Site 45
T431
D
Q
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 46
Y436
V
H
T
G
E
K
P
Y
E
C
I
E
C
G
K
Site 47
S446
I
E
C
G
K
A
F
S
N
S
S
S
L
A
Q
Site 48
S448
C
G
K
A
F
S
N
S
S
S
L
A
Q
H
Q
Site 49
S450
K
A
F
S
N
S
S
S
L
A
Q
H
Q
R
S
Site 50
S457
S
L
A
Q
H
Q
R
S
H
T
G
E
K
P
Y
Site 51
T459
A
Q
H
Q
R
S
H
T
G
E
K
P
Y
M
C
Site 52
Y464
S
H
T
G
E
K
P
Y
M
C
K
E
C
R
K
Site 53
T472
M
C
K
E
C
R
K
T
F
S
Q
N
A
G
L
Site 54
S474
K
E
C
R
K
T
F
S
Q
N
A
G
L
A
Q
Site 55
T487
A
Q
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 56
Y492
I
H
T
G
E
K
P
Y
E
C
N
V
C
G
K
Site 57
S504
C
G
K
A
F
S
Y
S
G
S
L
T
L
H
Q
Site 58
S506
K
A
F
S
Y
S
G
S
L
T
L
H
Q
R
I
Site 59
T508
F
S
Y
S
G
S
L
T
L
H
Q
R
I
H
T
Site 60
T515
T
L
H
Q
R
I
H
T
G
E
R
P
Y
E
C
Site 61
Y520
I
H
T
G
E
R
P
Y
E
C
K
D
C
R
K
Site 62
S528
E
C
K
D
C
R
K
S
F
R
Q
R
A
H
L
Site 63
T543
A
H
H
E
R
I
H
T
M
E
S
F
L
T
L
Site 64
S546
E
R
I
H
T
M
E
S
F
L
T
L
S
S
P
Site 65
T549
H
T
M
E
S
F
L
T
L
S
S
P
S
P
S
Site 66
S551
M
E
S
F
L
T
L
S
S
P
S
P
S
T
S
Site 67
S552
E
S
F
L
T
L
S
S
P
S
P
S
T
S
N
Site 68
S554
F
L
T
L
S
S
P
S
P
S
T
S
N
Q
L
Site 69
S556
T
L
S
S
P
S
P
S
T
S
N
Q
L
P
R
Site 70
T557
L
S
S
P
S
P
S
T
S
N
Q
L
P
R
P
Site 71
S558
S
S
P
S
P
S
T
S
N
Q
L
P
R
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation