PhosphoNET

           
Protein Info 
   
Short Name:  DOCK7
Full Name:  Dedicator of cytokinesis protein 7
Alias:  dedicator of cytokinesis 7; DOC7; KIAA1771; ZIR2
Type:  Guanine nucleotide exchange factor, misc.
Mass (Da):  242561
Number AA:  2140
UniProt ID:  Q96N67
International Prot ID:  IPI00183572
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0030424  GO:0045178  GO:0030426 Uniprot OncoNet
Molecular Function:  GO:0005525  GO:0048365  GO:0005085 PhosphoSite+ KinaseNET
Biological Process:  GO:0032863  GO:0007409  GO:0045200 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T14FAQKISRTVAAEVRK
Site 2S24AEVRKQISGQYSGSP
Site 3Y27RKQISGQYSGSPQLL
Site 4S28KQISGQYSGSPQLLK
Site 5S30ISGQYSGSPQLLKNL
Site 6T48GNISHHTTVPLTEAV
Site 7T52HHTTVPLTEAVDPVD
Site 8Y63DPVDLEDYLITHPLA
Site 9S92DDIEVVYSPRDCRTL
Site 10T98YSPRDCRTLVSAVPE
Site 11S101RDCRTLVSAVPEESE
Site 12Y120VRDCIRSYTEDWAIV
Site 13T136RKYHKLGTGFNPNTL
Site 14T142GTGFNPNTLDKQKER
Site 15S160LPKQVFESDEAPDGN
Site 16Y169EAPDGNSYQDDQDDL
Site 17S180QDDLKRRSMSIDDTP
Site 18S182DLKRRSMSIDDTPRG
Site 19T186RSMSIDDTPRGSWAC
Site 20S190IDDTPRGSWACSIFD
Site 21S194PRGSWACSIFDLKNS
Site 22T214LPNLLDRTPNEEIDR
Site 23S229QNDDQRKSNRHKELF
Site 24S241ELFALHPSPDEEEPI
Site 25S252EEPIERLSVPDIPKE
Site 26Y288IFASLALYDVKEKKK
Site 27Y301KKISENFYFDLNSEQ
Site 28S332LARSAIFSITYPSQD
Site 29Y362IGECAEPYMIFKEAD
Site 30T371IFKEADATKNKEKLE
Site 31S382EKLEKLKSQADQFCQ
Site 32S414NIVSSAGSLERDSTE
Site 33S419AGSLERDSTEVEIST
Site 34T420GSLERDSTEVEISTG
Site 35S425DSTEVEISTGERKGS
Site 36S432STGERKGSWSERRNS
Site 37S434GERKGSWSERRNSSI
Site 38S439SWSERRNSSIVGRRS
Site 39S440WSERRNSSIVGRRSL
Site 40S446SSIVGRRSLERTTSG
Site 41T450GRRSLERTTSGDDAC
Site 42T451RRSLERTTSGDDACN
Site 43S452RSLERTTSGDDACNL
Site 44T460GDDACNLTSFRPATL
Site 45S461DDACNLTSFRPATLT
Site 46T466LTSFRPATLTVTNFF
Site 47T468SFRPATLTVTNFFKQ
Site 48S481KQEGDRLSDEDLYKF
Site 49Y486RLSDEDLYKFLADMR
Site 50S496LADMRRPSSVLRRLR
Site 51S497ADMRRPSSVLRRLRP
Site 52T506LRRLRPITAQLKIDI
Site 53S514AQLKIDISPAPENPH
Site 54Y522PAPENPHYCLTPELL
Site 55T525ENPHYCLTPELLQVK
Site 56Y534ELLQVKLYPDSRVRP
Site 57S537QVKLYPDSRVRPTRE
Site 58T542PDSRVRPTREILEFP
Site 59Y554EFPARDVYVPNTTYR
Site 60T558RDVYVPNTTYRNLLY
Site 61Y565TTYRNLLYIYPQSLN
Site 62Y567YRNLLYIYPQSLNFA
Site 63S570LLYIYPQSLNFANRQ
Site 64S579NFANRQGSARNITVK
Site 65T584QGSARNITVKVQFMY
Site 66S606MPVIFGKSSCSEFSK
Site 67S607PVIFGKSSCSEFSKE
Site 68S609IFGKSSCSEFSKEAY
Site 69Y616SEFSKEAYTAVVYHN
Site 70Y621EAYTAVVYHNRSPDF
Site 71S625AVVYHNRSPDFHEEI
Site 72T639IKVKLPATLTDHHHL
Site 73Y651HHLLFTFYHVSCQQK
Site 74T661SCQQKQNTPLETPVG
Site 75T665KQNTPLETPVGYTWI
Site 76T682LQNGRLKTGQFCLPV
Site 77S690GQFCLPVSLEKPPQA
Site 78S699EKPPQAYSVLSPEVP
Site 79S702PQAYSVLSPEVPLPG
Site 80T732VAVSSIHTQDPYLDK
Site 81Y736SIHTQDPYLDKFFAL
Site 82S772NLENELKSSISALNS
Site 83S773LENELKSSISALNSS
Site 84S775NELKSSISALNSSQL
Site 85S780SISALNSSQLEPVVR
Site 86S843HDQHGRNSLLASYIH
Site 87S847GRNSLLASYIHYVFR
Site 88T858YVFRLPNTYPNSSSP
Site 89Y859VFRLPNTYPNSSSPG
Site 90S862LPNTYPNSSSPGPGG
Site 91S863PNTYPNSSSPGPGGL
Site 92S864NTYPNSSSPGPGGLG
Site 93S873GPGGLGGSVHYATMA
Site 94Y876GLGGSVHYATMARSA
Site 95T878GGSVHYATMARSAVR
Site 96S882HYATMARSAVRPASL
Site 97S888RSAVRPASLNLNRSR
Site 98S894ASLNLNRSRSLSNSN
Site 99S896LNLNRSRSLSNSNPD
Site 100S898LNRSRSLSNSNPDIS
Site 101S900RSRSLSNSNPDISGT
Site 102S905SNSNPDISGTPTSPD
Site 103T907SNPDISGTPTSPDDE
Site 104T909PDISGTPTSPDDEVR
Site 105S910DISGTPTSPDDEVRS
Site 106S917SPDDEVRSIIGSKGL
Site 107S921EVRSIIGSKGLDRSN
Site 108S927GSKGLDRSNSWVNTG
Site 109S929KGLDRSNSWVNTGGP
Site 110T933RSNSWVNTGGPKAAP
Site 111S943PKAAPWGSNPSPSAE
Site 112S946APWGSNPSPSAESTQ
Site 113S948WGSNPSPSAESTQAM
Site 114T952PSPSAESTQAMDRSC
Site 115S958STQAMDRSCNRMSSH
Site 116S963DRSCNRMSSHTETSS
Site 117S964RSCNRMSSHTETSSF
Site 118T966CNRMSSHTETSSFLQ
Site 119T968RMSSHTETSSFLQTL
Site 120S970SSHTETSSFLQTLTG
Site 121T974ETSSFLQTLTGRLPT
Site 122T976SSFLQTLTGRLPTKK
Site 123T981TLTGRLPTKKLFHEE
Site 124S999QWVVCSGSVRESALQ
Site 125S1003CSGSVRESALQQAWF
Site 126Y1024KSMVHHLYFNDKLEA
Site 127S1035KLEAPRKSRFPERFM
Site 128S1058TIASDIVSRFQKDTE
Site 129T1064VSRFQKDTEMVERLN
Site 130Y1098FSLIKSCYKQVSSKL
Site 131S1103SCYKQVSSKLYSLPN
Site 132Y1106KQVSSKLYSLPNPSV
Site 133S1107QVSSKLYSLPNPSVL
Site 134T1133CSHEHYVTLNLPCSL
Site 135T1142NLPCSLLTPPASPSP
Site 136S1146SLLTPPASPSPSVSS
Site 137S1148LTPPASPSPSVSSAT
Site 138S1150PPASPSPSVSSATSQ
Site 139S1152ASPSPSVSSATSQSS
Site 140S1153SPSPSVSSATSQSSG
Site 141T1155SPSVSSATSQSSGFS
Site 142S1156PSVSSATSQSSGFST
Site 143S1158VSSATSQSSGFSTNV
Site 144S1159SSATSQSSGFSTNVQ
Site 145S1162TSQSSGFSTNVQDQK
Site 146T1163SQSSGFSTNVQDQKI
Site 147S1221NMVHNLLSSHDSDPR
Site 148S1222MVHNLLSSHDSDPRY
Site 149S1225NLLSSHDSDPRYSDP
Site 150Y1229SHDSDPRYSDPQIKA
Site 151S1230HDSDPRYSDPQIKAR
Site 152Y1242KARVAMLYLPLIGII
Site 153Y1257METVPQLYDFTETHN
Site 154T1260VPQLYDFTETHNQRG
Site 155T1274GRPICIATDDYESES
Site 156Y1277ICIATDDYESESGSM
Site 157S1279IATDDYESESGSMIS
Site 158S1281TDDYESESGSMISQT
Site 159S1283DYESESGSMISQTVA
Site 160T1296VAMAIAGTSVPQLTR
Site 161S1297AMAIAGTSVPQLTRP
Site 162S1306PQLTRPGSFLLTSTS
Site 163T1310RPGSFLLTSTSGRQH
Site 164S1311PGSFLLTSTSGRQHT
Site 165S1313SFLLTSTSGRQHTTF
Site 166T1318STSGRQHTTFSAESS
Site 167T1319TSGRQHTTFSAESSR
Site 168S1321GRQHTTFSAESSRSL
Site 169S1324HTTFSAESSRSLLIC
Site 170T1342VLKNADETVLQKWFT
Site 171S1352QKWFTDLSVLQLNRL
Site 172Y1372LCVSCFEYKGKKVFE
Site 173S1383KVFERMNSLTFKKSK
Site 174T1385FERMNSLTFKKSKDM
Site 175S1389NSLTFKKSKDMRAKL
Site 176S1414RQEMVRRSRGQLGTY
Site 177T1420RSRGQLGTYTIASPP
Site 178Y1421SRGQLGTYTIASPPE
Site 179T1422RGQLGTYTIASPPER
Site 180S1425LGTYTIASPPERSPS
Site 181S1430IASPPERSPSGSAFG
Site 182S1432SPPERSPSGSAFGSQ
Site 183S1434PERSPSGSAFGSQEN
Site 184S1438PSGSAFGSQENLRWR
Site 185T1455MTHWRQNTEKLDKSR
Site 186S1461NTEKLDKSRAEIEHE
Site 187S1495EIVVQTVSVTESKES
Site 188S1499QTVSVTESKESILGG
Site 189T1530YLQHCFATQRALVSK
Site 190S1562LRLLRHCSSSIGTIR
Site 191S1563RLLRHCSSSIGTIRS
Site 192S1564LLRHCSSSIGTIRSH
Site 193T1567HCSSSIGTIRSHASA
Site 194S1570SSIGTIRSHASASLY
Site 195S1575IRSHASASLYLLMRQ
Site 196Y1577SHASASLYLLMRQNF
Site 197S1603QVTMSLSSLVGTSQN
Site 198T1607SLSSLVGTSQNFNEE
Site 199S1619NEEFLRRSLKTILTY
Site 200T1622FLRRSLKTILTYAEE
Site 201T1625RSLKTILTYAEEDLE
Site 202T1636EDLELRETTFPDQVQ
Site 203T1637DLELRETTFPDQVQD
Site 204T1656LHMILSDTVKMKEHQ
Site 205Y1674EMLIDLMYRIAKGYQ
Site 206Y1680MYRIAKGYQTSPDLR
Site 207S1683IAKGYQTSPDLRLTW
Site 208T1689TSPDLRLTWLQNMAG
Site 209S1699QNMAGKHSERSNHAE
Site 210Y1730SMLEDRKYLPVGCVT
Site 211S1749SSNVLEESAVSDDVV
Site 212S1752VLEESAVSDDVVSPD
Site 213S1757AVSDDVVSPDEEGIC
Site 214S1765PDEEGICSGKYFTES
Site 215Y1768EGICSGKYFTESGLV
Site 216S1826GKLQEAFSKIVHQST
Site 217Y1842WERMFGTYFRVGFYG
Site 218Y1848TYFRVGFYGTKFGDL
Site 219Y1862LDEQEFVYKEPAITK
Site 220T1868VYKEPAITKLAEISH
Site 221S1874ITKLAEISHRLEGFY
Site 222Y1881SHRLEGFYGERFGED
Site 223Y1915KAYIQITYVEPYFDT
Site 224Y1919QITYVEPYFDTYEMK
Site 225Y1923VEPYFDTYEMKDRIT
Site 226Y1931EMKDRITYFDKNYNL
Site 227Y1936ITYFDKNYNLRRFMY
Site 228Y1943YNLRRFMYCTPFTLD
Site 229T1945LRRFMYCTPFTLDGR
Site 230T1965HEQFKRKTILTTSHA
Site 231T1968FKRKTILTTSHAFPY
Site 232S1970RKTILTTSHAFPYIK
Site 233Y1975TTSHAFPYIKTRVNV
Site 234T2032LQGSVGTTVNQGPLE
Site 235S2046EVAQVFLSEIPSDPK
Site 236S2050VFLSEIPSDPKLFRH
Site 237T2069RLCFKDFTKRCEDAL
Site 238S2081DALRKNKSLIGPDQK
Site 239Y2090IGPDQKEYQRELERN
Site 240Y2098QRELERNYHRLKEAL
Site 241Y2117NRKIPQLYKAVLPVT
Site 242T2124YKAVLPVTCHRDSFS
Site 243S2129PVTCHRDSFSRMSLR
Site 244S2131TCHRDSFSRMSLRKM
Site 245S2134RDSFSRMSLRKMDL_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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