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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF578
Full Name:
Zinc finger protein 578
Alias:
Type:
Mass (Da):
42597
Number AA:
365
UniProt ID:
Q96N58
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
G
E
A
F
N
C
S
S
F
V
R
K
H
Q
I
Site 2
Y34
I
H
L
G
E
K
Q
Y
K
F
D
I
C
G
K
Site 3
Y48
K
V
F
N
E
K
R
Y
L
A
R
H
R
R
C
Site 4
T57
A
R
H
R
R
C
H
T
S
E
K
P
Y
K
C
Site 5
Y62
C
H
T
S
E
K
P
Y
K
C
N
E
C
G
K
Site 6
S70
K
C
N
E
C
G
K
S
F
S
Y
K
S
S
L
Site 7
S72
N
E
C
G
K
S
F
S
Y
K
S
S
L
T
C
Site 8
Y73
E
C
G
K
S
F
S
Y
K
S
S
L
T
C
H
Site 9
S75
G
K
S
F
S
Y
K
S
S
L
T
C
H
R
R
Site 10
S76
K
S
F
S
Y
K
S
S
L
T
C
H
R
R
C
Site 11
T85
T
C
H
R
R
C
H
T
G
E
K
P
Y
K
C
Site 12
Y90
C
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 13
S103
G
K
S
F
S
Y
K
S
S
L
T
C
H
H
R
Site 14
S104
K
S
F
S
Y
K
S
S
L
T
C
H
H
R
C
Site 15
T113
T
C
H
H
R
C
H
T
G
E
K
P
Y
K
C
Site 16
S128
N
E
C
G
K
S
F
S
Y
K
S
S
L
R
C
Site 17
Y129
E
C
G
K
S
F
S
Y
K
S
S
L
R
C
H
Site 18
S131
G
K
S
F
S
Y
K
S
S
L
R
C
H
R
R
Site 19
S132
K
S
F
S
Y
K
S
S
L
R
C
H
R
R
L
Site 20
T141
R
C
H
R
R
L
H
T
G
I
K
P
Y
K
C
Site 21
Y146
L
H
T
G
I
K
P
Y
K
C
N
E
C
G
K
Site 22
S159
G
K
M
F
G
Q
N
S
T
L
V
I
H
K
A
Site 23
Y174
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 24
S187
G
K
A
F
N
Q
Q
S
H
L
S
R
H
H
R
Site 25
T197
S
R
H
H
R
L
H
T
G
E
K
P
Y
K
C
Site 26
S215
V
K
A
F
I
H
Q
S
S
L
A
R
H
H
R
Site 27
S216
K
A
F
I
H
Q
S
S
L
A
R
H
H
R
L
Site 28
T225
A
R
H
H
R
L
H
T
G
E
K
S
Y
K
C
Site 29
S240
E
E
C
D
R
V
F
S
Q
K
S
N
L
E
R
Site 30
S243
D
R
V
F
S
Q
K
S
N
L
E
R
H
K
I
Site 31
Y258
I
H
T
G
E
K
P
Y
K
C
N
E
C
H
K
Site 32
T266
K
C
N
E
C
H
K
T
F
S
H
R
S
S
L
Site 33
S268
N
E
C
H
K
T
F
S
H
R
S
S
L
P
C
Site 34
S272
K
T
F
S
H
R
S
S
L
P
C
H
R
R
L
Site 35
S281
P
C
H
R
R
L
H
S
G
E
K
P
Y
K
C
Site 36
Y286
L
H
S
G
E
K
P
Y
K
C
N
E
C
G
K
Site 37
S299
G
K
T
F
N
V
Q
S
H
L
S
R
H
H
R
Site 38
S337
A
N
H
T
R
I
H
S
G
E
K
P
Y
K
C
Site 39
Y342
I
H
S
G
E
K
P
Y
K
C
N
E
C
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation