KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF681
Full Name:
Zinc finger protein 681
Alias:
Type:
Mass (Da):
66621
Number AA:
576
UniProt ID:
Q96N22
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
S
H
F
A
Q
H
F
S
P
E
Q
N
I
K
D
Site 2
S25
P
E
Q
N
I
K
D
S
F
Q
K
V
T
P
R
Site 3
T30
K
D
S
F
Q
K
V
T
P
R
R
Y
G
K
C
Site 4
Y34
Q
K
V
T
P
R
R
Y
G
K
C
E
H
E
N
Site 5
S45
E
H
E
N
L
Q
L
S
K
S
V
D
E
C
K
Site 6
S47
E
N
L
Q
L
S
K
S
V
D
E
C
K
V
Q
Site 7
T68
L
N
Q
C
L
P
T
T
Q
S
K
I
F
Q
C
Site 8
T96
N
G
H
K
V
R
H
T
R
K
K
P
F
K
Y
Site 9
Y103
T
R
K
K
P
F
K
Y
K
E
F
G
K
S
F
Site 10
S141
C
G
K
A
F
N
G
S
S
I
F
T
K
H
K
Site 11
S142
G
K
A
F
N
G
S
S
I
F
T
K
H
K
R
Site 12
T145
F
N
G
S
S
I
F
T
K
H
K
R
I
H
I
Site 13
Y157
I
H
I
G
E
K
S
Y
I
C
E
E
C
G
K
Site 14
Y179
L
T
T
H
K
I
I
Y
T
R
D
K
L
Y
K
Site 15
Y185
I
Y
T
R
D
K
L
Y
K
R
E
E
C
S
K
Site 16
S191
L
Y
K
R
E
E
C
S
K
A
F
N
L
S
S
Site 17
S197
C
S
K
A
F
N
L
S
S
H
I
T
T
H
T
Site 18
S198
S
K
A
F
N
L
S
S
H
I
T
T
H
T
I
Site 19
T202
N
L
S
S
H
I
T
T
H
T
I
I
H
T
G
Site 20
T204
S
S
H
I
T
T
H
T
I
I
H
T
G
E
N
Site 21
T229
F
N
Q
S
S
T
L
T
T
H
K
I
I
H
T
Site 22
Y243
T
R
E
K
L
N
E
Y
K
E
C
G
K
A
F
Site 23
S253
C
G
K
A
F
N
Q
S
S
H
L
T
R
H
K
Site 24
S254
G
K
A
F
N
Q
S
S
H
L
T
R
H
K
I
Site 25
T257
F
N
Q
S
S
H
L
T
R
H
K
I
I
H
T
Site 26
S309
C
G
K
A
F
R
Q
S
S
H
L
T
T
H
K
Site 27
S310
G
K
A
F
R
Q
S
S
H
L
T
T
H
K
I
Site 28
T313
F
R
Q
S
S
H
L
T
T
H
K
I
I
H
T
Site 29
T314
R
Q
S
S
H
L
T
T
H
K
I
I
H
T
G
Site 30
S337
C
G
K
A
F
N
K
S
S
H
L
T
R
H
K
Site 31
S338
G
K
A
F
N
K
S
S
H
L
T
R
H
K
S
Site 32
T341
F
N
K
S
S
H
L
T
R
H
K
S
I
H
T
Site 33
S345
S
H
L
T
R
H
K
S
I
H
T
G
E
K
P
Site 34
Y353
I
H
T
G
E
K
P
Y
Q
C
E
K
C
G
K
Site 35
S366
G
K
A
S
N
Q
S
S
N
L
T
E
H
K
N
Site 36
T369
S
N
Q
S
S
N
L
T
E
H
K
N
I
H
T
Site 37
Y381
I
H
T
E
E
K
P
Y
K
C
E
E
C
G
K
Site 38
S394
G
K
A
F
N
Q
F
S
N
L
T
T
H
K
R
Site 39
T398
N
Q
F
S
N
L
T
T
H
K
R
I
H
T
G
Site 40
T404
T
T
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 41
S421
C
G
K
A
F
N
Q
S
S
I
L
T
T
H
K
Site 42
S422
G
K
A
F
N
Q
S
S
I
L
T
T
H
K
R
Site 43
T425
F
N
Q
S
S
I
L
T
T
H
K
R
I
H
T
Site 44
T426
N
Q
S
S
I
L
T
T
H
K
R
I
H
T
G
Site 45
T432
T
T
H
K
R
I
H
T
G
E
K
S
Y
K
C
Site 46
S449
C
G
K
A
F
Y
R
S
S
K
L
T
E
H
K
Site 47
S450
G
K
A
F
Y
R
S
S
K
L
T
E
H
K
K
Site 48
T453
F
Y
R
S
S
K
L
T
E
H
K
K
I
H
T
Site 49
Y465
I
H
T
G
E
K
P
Y
T
C
E
E
C
G
K
Site 50
T466
H
T
G
E
K
P
Y
T
C
E
E
C
G
K
A
Site 51
S478
G
K
A
F
N
H
S
S
H
L
A
T
H
K
V
Site 52
T482
N
H
S
S
H
L
A
T
H
K
V
I
H
T
G
Site 53
Y493
I
H
T
G
E
K
P
Y
Q
C
E
E
C
G
K
Site 54
S506
G
K
A
F
N
Q
S
S
H
L
T
R
H
K
R
Site 55
T509
F
N
Q
S
S
H
L
T
R
H
K
R
I
H
T
Site 56
T516
T
R
H
K
R
I
H
T
G
E
K
P
Y
Q
C
Site 57
S533
C
G
K
A
F
N
Q
S
S
N
L
T
G
H
K
Site 58
S534
G
K
A
F
N
Q
S
S
N
L
T
G
H
K
K
Site 59
T537
F
N
Q
S
S
N
L
T
G
H
K
K
I
H
T
Site 60
S556
Y
K
P
K
R
C
N
S
D
F
E
N
T
S
K
Site 61
S562
N
S
D
F
E
N
T
S
K
F
S
K
H
K
R
Site 62
Y571
F
S
K
H
K
R
N
Y
A
G
E
K
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation