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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR52
Full Name:
WD repeat-containing protein 52
Alias:
FLJ11142; WD repeat domain 52; wdr52
Type:
Unknown function
Mass (Da):
111729
Number AA:
982
UniProt ID:
Q96MT7
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
K
E
P
D
D
Q
D
T
D
G
E
K
S
V
T
Site 2
S14
Q
D
T
D
G
E
K
S
V
T
S
K
S
D
G
Site 3
T16
T
D
G
E
K
S
V
T
S
K
S
D
G
K
K
Site 4
S17
D
G
E
K
S
V
T
S
K
S
D
G
K
K
S
Site 5
S19
E
K
S
V
T
S
K
S
D
G
K
K
S
L
R
Site 6
S24
S
K
S
D
G
K
K
S
L
R
S
S
K
S
E
Site 7
S27
D
G
K
K
S
L
R
S
S
K
S
E
S
R
S
Site 8
S28
G
K
K
S
L
R
S
S
K
S
E
S
R
S
P
Site 9
S30
K
S
L
R
S
S
K
S
E
S
R
S
P
V
Q
Site 10
S32
L
R
S
S
K
S
E
S
R
S
P
V
Q
E
D
Site 11
S34
S
S
K
S
E
S
R
S
P
V
Q
E
D
N
T
Site 12
T41
S
P
V
Q
E
D
N
T
F
L
E
D
D
T
D
Site 13
T47
N
T
F
L
E
D
D
T
D
E
T
F
T
K
G
Site 14
T50
L
E
D
D
T
D
E
T
F
T
K
G
E
G
S
Site 15
S57
T
F
T
K
G
E
G
S
Y
L
E
E
D
S
D
Site 16
S63
G
S
Y
L
E
E
D
S
D
E
E
R
L
E
G
Site 17
S71
D
E
E
R
L
E
G
S
L
S
S
F
Q
Y
G
Site 18
S73
E
R
L
E
G
S
L
S
S
F
Q
Y
G
D
L
Site 19
S74
R
L
E
G
S
L
S
S
F
Q
Y
G
D
L
Q
Site 20
Y77
G
S
L
S
S
F
Q
Y
G
D
L
Q
S
T
T
Site 21
S82
F
Q
Y
G
D
L
Q
S
T
T
V
P
Q
Q
T
Site 22
T83
Q
Y
G
D
L
Q
S
T
T
V
P
Q
Q
T
P
Site 23
T84
Y
G
D
L
Q
S
T
T
V
P
Q
Q
T
P
A
Site 24
T89
S
T
T
V
P
Q
Q
T
P
A
P
A
V
E
E
Site 25
S106
E
E
V
K
K
K
I
S
E
S
F
F
Y
D
Y
Site 26
Y111
K
I
S
E
S
F
F
Y
D
Y
M
E
L
A
S
Site 27
Y113
S
E
S
F
F
Y
D
Y
M
E
L
A
S
M
P
Site 28
S138
D
L
L
T
L
V
H
S
F
G
Y
D
C
R
K
Site 29
Y141
T
L
V
H
S
F
G
Y
D
C
R
K
R
A
N
Site 30
Y177
L
K
T
K
E
Q
I
Y
L
R
S
S
S
G
E
Site 31
S180
K
E
Q
I
Y
L
R
S
S
S
G
E
G
I
G
Site 32
S181
E
Q
I
Y
L
R
S
S
S
G
E
G
I
G
V
Site 33
Y197
G
V
H
P
H
K
T
Y
F
T
V
A
E
K
G
Site 34
T199
H
P
H
K
T
Y
F
T
V
A
E
K
G
S
F
Site 35
Y212
S
F
P
D
I
I
I
Y
E
Y
P
S
L
R
P
Site 36
Y214
P
D
I
I
I
Y
E
Y
P
S
L
R
P
Y
R
Site 37
Y220
E
Y
P
S
L
R
P
Y
R
V
L
R
D
G
T
Site 38
T227
Y
R
V
L
R
D
G
T
E
K
G
Y
A
Y
V
Site 39
Y231
R
D
G
T
E
K
G
Y
A
Y
V
D
F
N
Y
Site 40
Y233
G
T
E
K
G
Y
A
Y
V
D
F
N
Y
S
G
Site 41
Y238
Y
A
Y
V
D
F
N
Y
S
G
N
L
L
A
S
Site 42
S245
Y
S
G
N
L
L
A
S
V
G
S
N
P
D
Y
Site 43
S248
N
L
L
A
S
V
G
S
N
P
D
Y
T
L
T
Site 44
Y252
S
V
G
S
N
P
D
Y
T
L
T
I
W
N
W
Site 45
T268
E
E
Q
P
I
L
R
T
K
A
F
S
Q
E
V
Site 46
T279
S
Q
E
V
F
K
V
T
F
N
P
D
K
E
E
Site 47
T289
P
D
K
E
E
Q
L
T
T
S
G
S
G
H
I
Site 48
T290
D
K
E
E
Q
L
T
T
S
G
S
G
H
I
K
Site 49
S291
K
E
E
Q
L
T
T
S
G
S
G
H
I
K
F
Site 50
S293
E
Q
L
T
T
S
G
S
G
H
I
K
F
W
E
Site 51
S313
T
G
L
K
L
Q
G
S
L
G
R
F
G
K
T
Site 52
T322
G
R
F
G
K
T
I
T
T
D
I
E
G
Y
M
Site 53
S338
L
P
D
G
K
V
L
S
G
S
E
W
G
N
M
Site 54
S340
D
G
K
V
L
S
G
S
E
W
G
N
M
L
L
Site 55
T361
K
V
E
L
C
R
G
T
S
K
S
C
H
N
G
Site 56
S362
V
E
L
C
R
G
T
S
K
S
C
H
N
G
P
Site 57
S364
L
C
R
G
T
S
K
S
C
H
N
G
P
I
N
Site 58
Y388
I
T
V
G
S
D
G
Y
V
R
I
W
D
F
E
Site 59
T399
W
D
F
E
T
I
D
T
A
D
V
I
D
E
T
Site 60
S454
A
I
W
K
L
D
L
S
F
S
N
I
T
Q
D
Site 61
S456
W
K
L
D
L
S
F
S
N
I
T
Q
D
P
E
Site 62
T459
D
L
S
F
S
N
I
T
Q
D
P
E
C
L
F
Site 63
S467
Q
D
P
E
C
L
F
S
F
H
S
G
A
I
E
Site 64
Y497
L
D
C
S
V
R
I
Y
D
F
A
S
K
T
P
Site 65
S501
V
R
I
Y
D
F
A
S
K
T
P
L
A
Q
M
Site 66
T503
I
Y
D
F
A
S
K
T
P
L
A
Q
M
K
F
Site 67
T592
R
D
G
E
I
L
A
T
G
S
K
D
Q
T
V
Site 68
T598
A
T
G
S
K
D
Q
T
V
F
F
F
E
V
E
Site 69
Y608
F
F
E
V
E
R
D
Y
K
P
I
G
Y
I
N
Site 70
Y613
R
D
Y
K
P
I
G
Y
I
N
T
P
G
P
V
Site 71
S626
P
V
C
Q
L
M
W
S
P
M
S
H
P
E
S
Site 72
S629
Q
L
M
W
S
P
M
S
H
P
E
S
T
L
L
Site 73
S749
I
F
I
P
S
T
P
S
P
I
L
C
G
F
Y
Site 74
Y756
S
P
I
L
C
G
F
Y
S
E
P
G
K
F
W
Site 75
S757
P
I
L
C
G
F
Y
S
E
P
G
K
F
W
V
Site 76
S765
E
P
G
K
F
W
V
S
L
G
G
Y
D
S
G
Site 77
S771
V
S
L
G
G
Y
D
S
G
F
L
Y
H
C
E
Site 78
Y775
G
Y
D
S
G
F
L
Y
H
C
E
F
P
P
C
Site 79
S785
E
F
P
P
C
D
E
S
S
D
F
K
E
Q
K
Site 80
S786
F
P
P
C
D
E
S
S
D
F
K
E
Q
K
D
Site 81
Y800
D
E
P
I
D
V
R
Y
L
A
D
T
E
D
N
Site 82
T804
D
V
R
Y
L
A
D
T
E
D
N
P
I
Q
T
Site 83
Y833
K
N
G
A
I
R
V
Y
V
L
N
Q
N
D
P
Site 84
S841
V
L
N
Q
N
D
P
S
L
T
S
L
V
D
Y
Site 85
Y858
F
N
M
H
D
N
N
Y
G
C
I
K
S
I
A
Site 86
S903
D
M
K
A
K
V
P
S
P
R
F
G
I
E
T
Site 87
T910
S
P
R
F
G
I
E
T
E
P
I
P
E
D
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation