KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WDR65
Full Name:
WD repeat-containing protein 65
Alias:
Type:
Mass (Da):
78164
Number AA:
698
UniProt ID:
Q96MR6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S54
W
Q
K
F
I
P
G
S
E
K
S
Q
G
M
L
Site 2
S57
F
I
P
G
S
E
K
S
Q
G
M
L
A
L
S
Site 3
S64
S
Q
G
M
L
A
L
S
I
S
P
N
R
R
Y
Site 4
Y71
S
I
S
P
N
R
R
Y
L
A
I
S
E
T
V
Site 5
S75
N
R
R
Y
L
A
I
S
E
T
V
Q
E
K
P
Site 6
T77
R
Y
L
A
I
S
E
T
V
Q
E
K
P
A
I
Site 7
S112
F
Q
V
Q
K
F
I
S
M
A
F
S
P
D
S
Site 8
S119
S
M
A
F
S
P
D
S
K
Y
L
L
A
Q
T
Site 9
Y121
A
F
S
P
D
S
K
Y
L
L
A
Q
T
S
P
Site 10
T126
S
K
Y
L
L
A
Q
T
S
P
P
E
S
N
L
Site 11
S127
K
Y
L
L
A
Q
T
S
P
P
E
S
N
L
V
Site 12
Y135
P
P
E
S
N
L
V
Y
W
L
W
E
K
Q
K
Site 13
T151
M
A
I
V
R
I
D
T
Q
N
N
P
V
Y
Q
Site 14
Y157
D
T
Q
N
N
P
V
Y
Q
V
S
F
S
P
Q
Site 15
S160
N
N
P
V
Y
Q
V
S
F
S
P
Q
D
N
T
Site 16
S162
P
V
Y
Q
V
S
F
S
P
Q
D
N
T
Q
V
Site 17
T167
S
F
S
P
Q
D
N
T
Q
V
C
V
T
G
N
Site 18
T186
L
L
R
F
A
E
G
T
L
K
Q
T
S
F
Q
Site 19
S191
E
G
T
L
K
Q
T
S
F
Q
R
G
E
P
Q
Site 20
Y200
Q
R
G
E
P
Q
N
Y
L
A
H
T
W
V
A
Site 21
S225
G
K
L
F
L
F
E
S
G
D
Q
R
W
E
T
Site 22
T232
S
G
D
Q
R
W
E
T
S
I
M
V
K
E
P
Site 23
T240
S
I
M
V
K
E
P
T
N
G
S
K
S
L
D
Site 24
S245
E
P
T
N
G
S
K
S
L
D
V
I
Q
E
S
Site 25
S252
S
L
D
V
I
Q
E
S
E
S
L
I
E
F
P
Site 26
S262
L
I
E
F
P
P
V
S
S
P
L
P
S
Y
E
Site 27
S263
I
E
F
P
P
V
S
S
P
L
P
S
Y
E
Q
Site 28
S267
P
V
S
S
P
L
P
S
Y
E
Q
M
V
A
A
Site 29
Y268
V
S
S
P
L
P
S
Y
E
Q
M
V
A
A
S
Site 30
S276
E
Q
M
V
A
A
S
S
H
S
Q
M
S
M
P
Site 31
S278
M
V
A
A
S
S
H
S
Q
M
S
M
P
Q
V
Site 32
Y316
K
M
E
E
K
D
F
Y
R
E
S
R
E
I
R
Site 33
S319
E
K
D
F
Y
R
E
S
R
E
I
R
I
P
V
Site 34
S330
R
I
P
V
D
P
Q
S
N
D
P
S
Q
S
D
Site 35
S334
D
P
Q
S
N
D
P
S
Q
S
D
K
Q
D
V
Site 36
T352
C
F
S
P
S
E
E
T
L
V
A
S
T
S
K
Site 37
S356
S
E
E
T
L
V
A
S
T
S
K
N
Q
L
Y
Site 38
S358
E
T
L
V
A
S
T
S
K
N
Q
L
Y
S
I
Site 39
Y363
S
T
S
K
N
Q
L
Y
S
I
T
M
S
L
T
Site 40
S364
T
S
K
N
Q
L
Y
S
I
T
M
S
L
T
E
Site 41
S368
Q
L
Y
S
I
T
M
S
L
T
E
I
S
K
G
Site 42
T370
Y
S
I
T
M
S
L
T
E
I
S
K
G
E
P
Site 43
Y382
G
E
P
A
H
F
E
Y
L
M
Y
P
L
H
S
Site 44
Y418
R
S
I
R
L
W
N
Y
E
T
N
T
L
E
L
Site 45
T422
L
W
N
Y
E
T
N
T
L
E
L
F
K
E
Y
Site 46
Y429
T
L
E
L
F
K
E
Y
Q
E
E
A
Y
S
I
Site 47
S435
E
Y
Q
E
E
A
Y
S
I
S
L
H
P
S
G
Site 48
S437
Q
E
E
A
Y
S
I
S
L
H
P
S
G
H
F
Site 49
S465
L
L
I
D
D
I
R
S
F
K
E
Y
S
V
R
Site 50
Y469
D
I
R
S
F
K
E
Y
S
V
R
G
C
G
E
Site 51
S470
I
R
S
F
K
E
Y
S
V
R
G
C
G
E
C
Site 52
S478
V
R
G
C
G
E
C
S
F
S
N
G
G
H
L
Site 53
Y497
N
G
N
V
I
H
V
Y
T
T
T
S
L
E
N
Site 54
S507
T
S
L
E
N
I
S
S
L
K
G
H
T
G
K
Site 55
S525
I
V
W
N
A
D
D
S
K
L
I
S
G
G
T
Site 56
S529
A
D
D
S
K
L
I
S
G
G
T
D
G
A
V
Site 57
Y537
G
G
T
D
G
A
V
Y
E
W
N
L
S
T
G
Site 58
S542
A
V
Y
E
W
N
L
S
T
G
K
R
E
T
E
Site 59
T548
L
S
T
G
K
R
E
T
E
C
V
L
K
S
C
Site 60
T561
S
C
S
Y
N
C
V
T
V
S
P
D
A
K
I
Site 61
Y623
G
T
I
R
A
M
K
Y
P
L
P
L
Q
K
E
Site 62
Y634
L
Q
K
E
F
N
E
Y
Q
A
H
A
G
P
I
Site 63
S645
A
G
P
I
T
K
V
S
R
A
L
S
P
G
T
Site 64
S649
T
K
V
S
R
A
L
S
P
G
T
Q
S
H
T
Site 65
T652
S
R
A
L
S
P
G
T
Q
S
H
T
C
L
L
Site 66
S654
A
L
S
P
G
T
Q
S
H
T
C
L
L
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation