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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZSWIM3
Full Name:
Zinc finger SWIM domain-containing protein 3
Alias:
C20orf164; DJ337O18.7; Zinc finger, SWIM-type containing 3
Type:
Mass (Da):
79450
Number AA:
UniProt ID:
Q96MP5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
E
L
G
S
C
F
K
T
Y
E
D
F
K
E
C
Site 2
Y10
L
G
S
C
F
K
T
Y
E
D
F
K
E
C
F
Site 3
S18
E
D
F
K
E
C
F
S
A
Y
K
R
E
N
R
Site 4
Y20
F
K
E
C
F
S
A
Y
K
R
E
N
R
C
S
Site 5
S27
Y
K
R
E
N
R
C
S
F
I
L
R
D
C
V
Site 6
S46
H
N
L
N
H
G
T
S
I
R
E
D
I
L
Y
Site 7
T63
V
K
F
V
C
I
R
T
Q
S
N
R
K
R
T
Site 8
S65
F
V
C
I
R
T
Q
S
N
R
K
R
T
R
E
Site 9
T70
T
Q
S
N
R
K
R
T
R
E
A
D
M
C
P
Site 10
Y79
E
A
D
M
C
P
A
Y
L
L
L
R
Y
N
E
Site 11
Y84
P
A
Y
L
L
L
R
Y
N
E
R
L
D
R
L
Site 12
S94
R
L
D
R
L
F
I
S
E
L
N
T
Q
H
I
Site 13
T98
L
F
I
S
E
L
N
T
Q
H
I
H
G
D
S
Site 14
S105
T
Q
H
I
H
G
D
S
K
V
A
S
P
G
G
Site 15
S109
H
G
D
S
K
V
A
S
P
G
G
D
T
T
G
Site 16
T114
V
A
S
P
G
G
D
T
T
G
K
S
Q
K
T
Site 17
S118
G
G
D
T
T
G
K
S
Q
K
T
M
C
L
Q
Site 18
T133
R
L
Q
P
V
Q
P
T
T
K
K
D
L
D
T
Site 19
T134
L
Q
P
V
Q
P
T
T
K
K
D
L
D
T
A
Site 20
T140
T
T
K
K
D
L
D
T
A
E
K
S
L
V
E
Site 21
S144
D
L
D
T
A
E
K
S
L
V
E
P
S
F
C
Site 22
S149
E
K
S
L
V
E
P
S
F
C
L
D
K
V
Q
Site 23
S158
C
L
D
K
V
Q
V
S
S
K
P
E
Q
E
G
Site 24
S159
L
D
K
V
Q
V
S
S
K
P
E
Q
E
G
I
Site 25
T167
K
P
E
Q
E
G
I
T
P
S
D
L
A
K
I
Site 26
S169
E
Q
E
G
I
T
P
S
D
L
A
K
I
A
K
Site 27
S188
F
L
K
V
D
E
G
S
M
A
S
F
S
V
G
Site 28
S191
V
D
E
G
S
M
A
S
F
S
V
G
D
S
Q
Site 29
S193
E
G
S
M
A
S
F
S
V
G
D
S
Q
H
L
Site 30
S197
A
S
F
S
V
G
D
S
Q
H
L
D
R
L
S
Site 31
S204
S
Q
H
L
D
R
L
S
F
Q
S
S
K
M
T
Site 32
S207
L
D
R
L
S
F
Q
S
S
K
M
T
D
L
F
Site 33
S208
D
R
L
S
F
Q
S
S
K
M
T
D
L
F
I
Site 34
T211
S
F
Q
S
S
K
M
T
D
L
F
I
R
F
P
Site 35
Y235
N
T
Q
G
H
I
L
Y
A
F
L
V
E
N
K
Site 36
S246
V
E
N
K
E
R
E
S
R
V
V
H
F
A
V
Site 37
S274
S
I
F
T
E
F
N
S
D
W
P
K
V
K
V
Site 38
Y290
F
V
D
P
S
F
H
Y
R
A
I
L
Q
E
I
Site 39
Y308
A
R
I
L
L
S
I
Y
H
T
T
R
L
L
E
Site 40
T311
L
L
S
I
Y
H
T
T
R
L
L
E
K
K
L
Site 41
S321
L
E
K
K
L
H
R
S
S
A
N
P
S
F
K
Site 42
S322
E
K
K
L
H
R
S
S
A
N
P
S
F
K
R
Site 43
S326
H
R
S
S
A
N
P
S
F
K
R
L
M
K
E
Site 44
T342
L
R
E
A
V
F
V
T
S
E
A
S
L
K
N
Site 45
S346
V
F
V
T
S
E
A
S
L
K
N
L
C
Q
M
Site 46
S354
L
K
N
L
C
Q
M
S
Q
A
V
L
D
E
D
Site 47
Y378
F
T
C
E
L
L
W
Y
M
H
V
R
K
G
L
Site 48
T390
K
G
L
L
A
C
N
T
Y
M
D
S
L
D
I
Site 49
Y391
G
L
L
A
C
N
T
Y
M
D
S
L
D
I
V
Site 50
S394
A
C
N
T
Y
M
D
S
L
D
I
V
T
S
K
Site 51
S400
D
S
L
D
I
V
T
S
K
V
S
S
L
F
R
Site 52
S404
I
V
T
S
K
V
S
S
L
F
R
E
Q
Q
S
Site 53
S411
S
L
F
R
E
Q
Q
S
L
L
D
C
I
L
C
Site 54
Y422
C
I
L
C
F
V
D
Y
I
D
F
F
N
T
K
Site 55
T428
D
Y
I
D
F
F
N
T
K
G
L
K
N
L
P
Site 56
T436
K
G
L
K
N
L
P
T
P
P
P
K
L
K
R
Site 57
S448
L
K
R
A
R
P
A
S
M
P
L
K
S
K
K
Site 58
S466
I
C
G
E
S
L
T
S
L
P
A
E
E
T
K
Site 59
T472
T
S
L
P
A
E
E
T
K
P
D
A
Q
Q
V
Site 60
S485
Q
V
Q
V
Q
Q
Q
S
Q
V
P
P
S
Q
V
Site 61
S490
Q
Q
S
Q
V
P
P
S
Q
V
G
M
L
D
T
Site 62
T497
S
Q
V
G
M
L
D
T
L
H
Q
S
G
S
E
Site 63
S501
M
L
D
T
L
H
Q
S
G
S
E
L
A
Y
K
Site 64
S503
D
T
L
H
Q
S
G
S
E
L
A
Y
K
L
C
Site 65
Y507
Q
S
G
S
E
L
A
Y
K
L
C
H
N
E
W
Site 66
S520
E
W
E
V
V
Q
N
S
T
H
L
V
D
M
A
Site 67
S530
L
V
D
M
A
G
S
S
V
D
V
Q
L
L
E
Site 68
S539
D
V
Q
L
L
E
D
S
H
Q
V
S
K
D
G
Site 69
S543
L
E
D
S
H
Q
V
S
K
D
G
C
S
C
S
Site 70
S548
Q
V
S
K
D
G
C
S
C
S
C
S
F
Q
Q
Site 71
S550
S
K
D
G
C
S
C
S
C
S
F
Q
Q
W
Y
Site 72
S552
D
G
C
S
C
S
C
S
F
Q
Q
W
Y
H
L
Site 73
Y557
S
C
S
F
Q
Q
W
Y
H
L
P
C
R
H
I
Site 74
T570
H
I
L
A
L
L
H
T
S
Q
Q
P
V
G
E
Site 75
Y588
C
R
R
W
Q
K
K
Y
Q
Y
L
L
G
P
N
Site 76
Y590
R
W
Q
K
K
Y
Q
Y
L
L
G
P
N
G
E
Site 77
T607
D
R
G
M
V
P
N
T
G
Q
P
E
K
Q
G
Site 78
S623
N
D
M
I
Q
D
L
S
R
E
L
A
N
L
L
Site 79
T633
L
A
N
L
L
M
Q
T
E
G
P
E
L
E
E
Site 80
Y642
G
P
E
L
E
E
R
Y
S
T
L
R
K
I
V
Site 81
S643
P
E
L
E
E
R
Y
S
T
L
R
K
I
V
D
Site 82
T644
E
L
E
E
R
Y
S
T
L
R
K
I
V
D
I
Site 83
S656
V
D
I
W
A
G
P
S
Q
P
S
E
L
F
Q
Site 84
S659
W
A
G
P
S
Q
P
S
E
L
F
Q
Q
P
G
Site 85
T691
G
E
G
F
P
P
A
T
A
V
M
H
Y
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation