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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGBL1
Full Name:
Cytosolic carboxypeptidase 4
Alias:
ATP/GTP-binding protein-like 1
Type:
Mass (Da):
120281
Number AA:
1066
UniProt ID:
Q96MI9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
L
L
Q
T
L
V
D
T
A
R
T
A
P
P
D
Site 2
T106
E
L
L
F
K
V
I
T
P
Y
T
R
K
R
T
Site 3
Y108
L
F
K
V
I
T
P
Y
T
R
K
R
T
Q
A
Site 4
T113
T
P
Y
T
R
K
R
T
Q
A
I
R
A
A
T
Site 5
S131
A
A
L
L
K
S
K
S
N
G
R
R
A
V
N
Site 6
Y141
R
R
A
V
N
R
G
Y
V
T
S
L
L
G
L
Site 7
S144
V
N
R
G
Y
V
T
S
L
L
G
L
H
Q
D
Site 8
Y161
S
H
D
T
A
N
A
Y
V
Q
I
R
R
G
L
Site 9
S180
R
H
I
A
A
L
R
S
G
R
E
A
F
L
A
Site 10
S206
Q
N
C
L
D
D
K
S
M
E
P
V
I
S
V
Site 11
T246
P
V
P
G
C
I
T
T
E
P
P
H
D
L
P
Site 12
S269
D
D
E
V
D
K
D
S
D
T
E
D
G
K
V
Site 13
T271
E
V
D
K
D
S
D
T
E
D
G
K
V
E
D
Site 14
T283
V
E
D
D
D
L
E
T
D
V
N
K
L
S
S
Site 15
S289
E
T
D
V
N
K
L
S
S
K
P
G
L
D
R
Site 16
Y304
P
E
E
E
L
M
Q
Y
E
V
M
C
L
E
L
Site 17
S314
M
C
L
E
L
S
Y
S
F
E
E
L
Q
S
K
Site 18
S328
K
L
G
D
D
L
N
S
E
K
T
Q
Y
A
N
Site 19
Y333
L
N
S
E
K
T
Q
Y
A
N
H
H
H
I
P
Site 20
S345
H
I
P
A
A
A
S
S
K
Q
H
C
Y
S
K
Site 21
Y350
A
S
S
K
Q
H
C
Y
S
K
D
Q
S
S
C
Site 22
S351
S
S
K
Q
H
C
Y
S
K
D
Q
S
S
C
G
Site 23
S355
H
C
Y
S
K
D
Q
S
S
C
G
Q
E
R
E
Site 24
S356
C
Y
S
K
D
Q
S
S
C
G
Q
E
R
E
Y
Site 25
Y363
S
C
G
Q
E
R
E
Y
A
V
Q
T
S
L
L
Site 26
T379
R
V
K
T
G
R
S
T
V
H
L
G
S
K
K
Site 27
S384
R
S
T
V
H
L
G
S
K
K
N
P
G
V
N
Site 28
Y393
K
N
P
G
V
N
L
Y
Q
N
V
Q
S
N
S
Site 29
S400
Y
Q
N
V
Q
S
N
S
L
R
R
D
S
S
E
Site 30
S405
S
N
S
L
R
R
D
S
S
E
S
E
I
P
D
Site 31
S406
N
S
L
R
R
D
S
S
E
S
E
I
P
D
I
Site 32
S408
L
R
R
D
S
S
E
S
E
I
P
D
I
Q
A
Site 33
S416
E
I
P
D
I
Q
A
S
P
K
A
D
A
W
D
Site 34
S435
F
C
P
R
M
S
A
S
F
S
N
S
T
R
T
Site 35
S437
P
R
M
S
A
S
F
S
N
S
T
R
T
R
E
Site 36
S439
M
S
A
S
F
S
N
S
T
R
T
R
E
V
V
Site 37
Y466
R
V
P
F
H
D
P
Y
L
Y
M
A
K
A
R
Site 38
Y468
P
F
H
D
P
Y
L
Y
M
A
K
A
R
R
T
Site 39
T475
Y
M
A
K
A
R
R
T
S
S
V
V
D
F
K
Site 40
S476
M
A
K
A
R
R
T
S
S
V
V
D
F
K
M
Site 41
S477
A
K
A
R
R
T
S
S
V
V
D
F
K
M
M
Site 42
T497
W
G
H
C
P
P
P
T
T
Q
P
M
L
E
R
Site 43
T498
G
H
C
P
P
P
T
T
Q
P
M
L
E
R
K
Site 44
S552
S
N
C
L
R
F
F
S
K
F
E
S
G
N
L
Site 45
S556
R
F
F
S
K
F
E
S
G
N
L
R
K
A
I
Site 46
Y616
K
P
N
S
Q
F
N
Y
G
M
Q
P
T
L
Y
Site 47
T634
E
A
L
L
G
K
P
T
W
I
R
T
G
H
E
Site 48
Y644
R
T
G
H
E
I
C
Y
Y
K
N
H
Y
R
Q
Site 49
Y645
T
G
H
E
I
C
Y
Y
K
N
H
Y
R
Q
S
Site 50
S652
Y
K
N
H
Y
R
Q
S
T
A
V
A
G
G
A
Site 51
T653
K
N
H
Y
R
Q
S
T
A
V
A
G
G
A
S
Site 52
Y681
P
H
S
E
D
V
C
Y
L
A
Y
H
Y
P
Y
Site 53
Y684
E
D
V
C
Y
L
A
Y
H
Y
P
Y
T
Y
T
Site 54
Y690
A
Y
H
Y
P
Y
T
Y
T
A
L
M
T
H
L
Site 55
S703
H
L
D
I
L
E
K
S
V
N
L
K
E
V
Y
Site 56
Y710
S
V
N
L
K
E
V
Y
F
R
Q
D
V
L
C
Site 57
T719
R
Q
D
V
L
C
Q
T
L
G
G
N
P
C
P
Site 58
S736
T
I
T
A
M
P
E
S
N
S
D
E
H
L
E
Site 59
S738
T
A
M
P
E
S
N
S
D
E
H
L
E
Q
F
Site 60
Y750
E
Q
F
R
H
R
P
Y
Q
V
I
T
A
R
V
Site 61
T754
H
R
P
Y
Q
V
I
T
A
R
V
H
P
G
E
Site 62
S765
H
P
G
E
S
N
A
S
W
V
M
K
G
T
L
Site 63
S810
I
N
G
N
H
R
C
S
L
S
G
E
D
L
N
Site 64
S812
G
N
H
R
C
S
L
S
G
E
D
L
N
R
Q
Site 65
S822
D
L
N
R
Q
W
L
S
P
S
A
H
L
Q
P
Site 66
S824
N
R
Q
W
L
S
P
S
A
H
L
Q
P
T
I
Site 67
Y832
A
H
L
Q
P
T
I
Y
H
A
K
G
L
L
Y
Site 68
Y839
Y
H
A
K
G
L
L
Y
H
L
S
S
I
G
R
Site 69
S842
K
G
L
L
Y
H
L
S
S
I
G
R
S
P
V
Site 70
Y866
Q
K
K
N
V
F
L
Y
G
C
S
I
K
E
T
Site 71
S918
C
S
F
L
V
E
K
S
R
A
S
T
A
R
V
Site 72
T922
V
E
K
S
R
A
S
T
A
R
V
V
V
W
R
Site 73
S934
V
W
R
E
M
G
V
S
R
S
Y
T
M
E
S
Site 74
S936
R
E
M
G
V
S
R
S
Y
T
M
E
S
S
Y
Site 75
Y937
E
M
G
V
S
R
S
Y
T
M
E
S
S
Y
C
Site 76
T938
M
G
V
S
R
S
Y
T
M
E
S
S
Y
C
G
Site 77
Y943
S
Y
T
M
E
S
S
Y
C
G
C
N
Q
G
P
Site 78
Y951
C
G
C
N
Q
G
P
Y
Q
C
T
Q
R
L
L
Site 79
T954
N
Q
G
P
Y
Q
C
T
Q
R
L
L
E
R
T
Site 80
T961
T
Q
R
L
L
E
R
T
K
N
E
R
A
H
P
Site 81
S1004
E
L
K
S
A
S
C
S
H
Q
L
L
A
Q
A
Site 82
S1031
Q
H
L
Q
R
L
K
S
S
N
F
L
P
K
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation