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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNHD1
Full Name:
Dynein heavy chain domain-containing protein 1
Alias:
Dynein heavy chain domain 1-like protein;Protein CCDC35
Type:
Mass (Da):
112942
Number AA:
1021
UniProt ID:
Q96M86
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
H
E
I
L
C
R
E
Y
P
E
L
E
T
R
W
Site 2
S159
V
T
K
Q
A
L
D
S
M
K
P
R
E
I
N
Site 3
S173
N
H
G
E
D
L
A
S
H
L
L
Q
L
R
A
Site 4
T183
L
Q
L
R
A
H
L
T
R
Q
L
L
G
S
T
Site 5
S232
L
W
P
G
L
A
A
S
P
S
T
V
H
S
K
Site 6
S234
P
G
L
A
A
S
P
S
T
V
H
S
K
P
V
Site 7
T235
G
L
A
A
S
P
S
T
V
H
S
K
P
V
S
Site 8
S238
A
S
P
S
T
V
H
S
K
P
V
S
D
V
A
Site 9
S242
T
V
H
S
K
P
V
S
D
V
A
R
P
A
W
Site 10
S279
A
S
L
A
G
H
S
S
A
W
Q
A
Y
L
S
Site 11
Y284
H
S
S
A
W
Q
A
Y
L
S
L
S
S
T
V
Site 12
T340
G
R
P
L
D
E
N
T
Y
A
P
T
M
P
F
Site 13
Y341
R
P
L
D
E
N
T
Y
A
P
T
M
P
F
K
Site 14
S350
P
T
M
P
F
K
H
S
Q
A
T
Q
P
M
L
Site 15
S367
L
P
P
P
G
H
P
S
A
T
L
H
P
L
T
Site 16
S454
K
V
V
A
D
L
E
S
E
Q
L
L
D
Q
P
Site 17
S463
Q
L
L
D
Q
P
E
S
R
N
V
S
T
V
H
Site 18
S467
Q
P
E
S
R
N
V
S
T
V
H
R
D
F
R
Site 19
Y522
E
L
A
Q
Q
V
L
Y
M
Q
P
P
T
Q
A
Site 20
Y545
L
L
L
H
R
Q
L
Y
G
T
R
L
Q
A
H
Site 21
T547
L
H
R
Q
L
Y
G
T
R
L
Q
A
H
R
G
Site 22
S557
Q
A
H
R
G
R
W
S
Q
V
T
L
T
Q
V
Site 23
T560
R
G
R
W
S
Q
V
T
L
T
Q
V
L
Q
T
Site 24
T562
R
W
S
Q
V
T
L
T
Q
V
L
Q
T
Q
D
Site 25
S574
T
Q
D
Q
L
W
A
S
L
S
N
P
R
A
A
Site 26
S576
D
Q
L
W
A
S
L
S
N
P
R
A
A
M
Q
Site 27
T598
Y
G
G
P
L
G
D
T
E
D
R
E
A
L
I
Site 28
S606
E
D
R
E
A
L
I
S
L
T
Q
A
C
L
S
Site 29
S616
Q
A
C
L
S
P
S
S
G
S
W
V
Q
P
H
Site 30
T624
G
S
W
V
Q
P
H
T
P
Q
S
L
L
A
T
Site 31
S656
A
Q
M
H
L
L
P
S
P
P
E
P
R
L
C
Site 32
S666
E
P
R
L
C
G
L
S
E
G
P
Q
A
W
L
Site 33
S683
R
Q
S
R
A
L
L
S
A
L
Q
R
S
S
P
Site 34
S689
L
S
A
L
Q
R
S
S
P
V
W
V
P
E
S
Site 35
S696
S
P
V
W
V
P
E
S
R
R
G
A
Q
L
A
Site 36
S720
Q
V
N
R
R
L
E
S
L
Q
D
L
L
T
H
Site 37
T726
E
S
L
Q
D
L
L
T
H
V
I
R
Q
D
E
Site 38
S734
H
V
I
R
Q
D
E
S
D
A
P
W
S
V
L
Site 39
S739
D
E
S
D
A
P
W
S
V
L
G
P
N
A
R
Site 40
S761
E
T
E
A
L
E
L
S
Q
L
V
G
T
L
Q
Site 41
S786
K
G
A
P
P
C
P
S
R
R
C
A
A
V
A
Site 42
S824
W
H
W
L
R
Q
L
S
R
R
G
Q
L
L
V
Site 43
S841
L
G
V
G
A
D
A
S
S
D
V
P
E
R
V
Site 44
S842
G
V
G
A
D
A
S
S
D
V
P
E
R
V
F
Site 45
S852
P
E
R
V
F
H
L
S
A
F
R
H
P
R
R
Site 46
S877
L
D
Q
N
V
P
S
S
N
F
P
G
S
R
G
Site 47
S882
P
S
S
N
F
P
G
S
R
G
S
V
S
S
Q
Site 48
S885
N
F
P
G
S
R
G
S
V
S
S
Q
L
Q
Y
Site 49
S887
P
G
S
R
G
S
V
S
S
Q
L
Q
Y
K
R
Site 50
S888
G
S
R
G
S
V
S
S
Q
L
Q
Y
K
R
L
Site 51
Y892
S
V
S
S
Q
L
Q
Y
K
R
L
E
M
N
S
Site 52
S899
Y
K
R
L
E
M
N
S
N
P
L
H
F
R
V
Site 53
T913
V
E
N
G
P
N
P
T
V
P
E
R
G
L
L
Site 54
S941
I
A
G
A
L
Q
D
S
P
S
S
Q
P
S
P
Site 55
S943
G
A
L
Q
D
S
P
S
S
Q
P
S
P
L
P
Site 56
S944
A
L
Q
D
S
P
S
S
Q
P
S
P
L
P
P
Site 57
S947
D
S
P
S
S
Q
P
S
P
L
P
P
V
S
I
Site 58
S953
P
S
P
L
P
P
V
S
I
S
T
Q
A
P
G
Site 59
S955
S
F
R
S
S
K
S
S
F
L
N
R
S
Q
V
Site 60
T956
L
P
P
V
S
I
S
T
Q
A
P
G
T
S
D
Site 61
S960
K
S
S
F
L
N
R
S
Q
V
D
S
D
D
V
Site 62
S962
S
T
Q
A
P
G
T
S
D
L
P
A
P
A
D
Site 63
S975
S
F
R
S
S
K
S
S
F
L
N
R
S
Q
V
Site 64
S980
K
S
S
F
L
N
R
S
Q
V
D
S
D
D
V
Site 65
S984
L
N
R
S
Q
V
D
S
D
D
V
P
D
K
C
Site 66
T1004
L
P
L
P
T
K
L
T
P
N
T
C
V
Q
R
Site 67
T1007
P
T
K
L
T
P
N
T
C
V
Q
R
R
V
H
Site 68
S1017
Q
R
R
V
H
V
C
S
P
P
L
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation