PhosphoNET

           
Protein Info 
   
Short Name:  HYLS1
Full Name:  Hydrolethalus syndrome protein 1
Alias:  FLJ32915; Hydrolethalus syndrome 1
Type:  Unknown function
Mass (Da):  34359
Number AA:  299
UniProt ID:  Q96M11
International Prot ID:  not found
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S45DVRREAQSIQYDPYS
Site 2Y48REAQSIQYDPYSKAS
Site 3Y51QSIQYDPYSKASVAP
Site 4S52SIQYDPYSKASVAPG
Site 5S55YDPYSKASVAPGKRP
Site 6Y70ALPVQLQYPHVESNV
Site 7S75LQYPHVESNVPSETV
Site 8S79HVESNVPSETVSEAS
Site 9T81ESNVPSETVSEASQR
Site 10S83NVPSETVSEASQRLR
Site 11S86SETVSEASQRLRKPV
Site 12T110PDGEVLVTDESIISE
Site 13S113EVLVTDESIISESES
Site 14S116VTDESIISESESGTE
Site 15S120SIISESESGTENDQD
Site 16T122ISESESGTENDQDLW
Site 17S146QFQEDKESSFDVSQK
Site 18S147FQEDKESSFDVSQKF
Site 19S151KESSFDVSQKFNLPH
Site 20Y160KFNLPHEYQGISQDQ
Site 21S164PHEYQGISQDQLICS
Site 22S171SQDQLICSLQREGMG
Site 23S179LQREGMGSPAYEQDL
Site 24Y182EGMGSPAYEQDLIVA
Site 25S204LPKLDQLSRNRGKTD
Site 26T210LSRNRGKTDRVARYF
Site 27Y216KTDRVARYFEYKRDW
Site 28Y219RVARYFEYKRDWDSI
Site 29S225EYKRDWDSIRLPGED
Site 30S253LCRAEPQSKPQHIYV
Site 31Y259QSKPQHIYVPNNYLV
Site 32Y264HIYVPNNYLVPTEKK
Site 33S273VPTEKKRSALRWGVR
Site 34S297RKLPFPLSPS_____
Site 35S299LPFPLSPS_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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