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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF354B
Full Name:
Zinc finger protein 354B
Alias:
Type:
Mass (Da):
70529
Number AA:
612
UniProt ID:
Q96LW1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
E
W
R
K
L
A
P
S
Q
R
N
L
Y
R
D
Site 2
Y39
A
P
S
Q
R
N
L
Y
R
D
V
M
L
E
N
Site 3
Y47
R
D
V
M
L
E
N
Y
R
N
L
V
S
L
G
Site 4
S52
E
N
Y
R
N
L
V
S
L
G
L
S
F
T
K
Site 5
S79
P
W
E
V
E
K
D
S
S
G
V
S
S
L
G
Site 6
S80
W
E
V
E
K
D
S
S
G
V
S
S
L
G
C
Site 7
S83
E
K
D
S
S
G
V
S
S
L
G
C
K
S
T
Site 8
S84
K
D
S
S
G
V
S
S
L
G
C
K
S
T
P
Site 9
S89
V
S
S
L
G
C
K
S
T
P
K
M
T
K
S
Site 10
T90
S
S
L
G
C
K
S
T
P
K
M
T
K
S
T
Site 11
S96
S
T
P
K
M
T
K
S
T
Q
T
Q
D
S
F
Site 12
S102
K
S
T
Q
T
Q
D
S
F
Q
E
Q
I
R
K
Site 13
T153
V
A
H
T
K
I
L
T
V
D
R
S
H
K
N
Site 14
S157
K
I
L
T
V
D
R
S
H
K
N
V
E
F
G
Site 15
T184
Q
R
F
A
K
E
K
T
P
S
K
C
E
I
Q
Site 16
S186
F
A
K
E
K
T
P
S
K
C
E
I
Q
R
N
Site 17
S194
K
C
E
I
Q
R
N
S
F
K
Q
N
S
N
L
Site 18
T209
L
N
Q
S
K
I
K
T
A
E
K
R
Y
K
C
Site 19
T218
E
K
R
Y
K
C
S
T
C
E
K
A
F
I
H
Site 20
S227
E
K
A
F
I
H
N
S
S
L
R
K
H
Q
K
Site 21
S228
K
A
F
I
H
N
S
S
L
R
K
H
Q
K
N
Site 22
S252
K
E
C
L
K
A
F
S
Q
S
S
A
L
I
Q
Site 23
T263
A
L
I
Q
H
Q
R
T
H
T
G
E
K
P
Y
Site 24
T265
I
Q
H
Q
R
T
H
T
G
E
K
P
Y
I
C
Site 25
Y270
T
H
T
G
E
K
P
Y
I
C
K
E
C
G
K
Site 26
S280
K
E
C
G
K
A
F
S
H
S
A
S
L
C
K
Site 27
S282
C
G
K
A
F
S
H
S
A
S
L
C
K
H
L
Site 28
S284
K
A
F
S
H
S
A
S
L
C
K
H
L
R
T
Site 29
T291
S
L
C
K
H
L
R
T
H
T
V
E
K
C
Y
Site 30
T293
C
K
H
L
R
T
H
T
V
E
K
C
Y
R
C
Site 31
Y298
T
H
T
V
E
K
C
Y
R
C
K
E
C
G
K
Site 32
S306
R
C
K
E
C
G
K
S
F
S
R
R
S
G
L
Site 33
S308
K
E
C
G
K
S
F
S
R
R
S
G
L
F
I
Site 34
S311
G
K
S
F
S
R
R
S
G
L
F
I
H
Q
K
Site 35
Y328
A
Q
E
N
P
H
K
Y
N
P
G
R
K
A
S
Site 36
S335
Y
N
P
G
R
K
A
S
S
Y
S
T
S
L
S
Site 37
S336
N
P
G
R
K
A
S
S
Y
S
T
S
L
S
G
Site 38
Y337
P
G
R
K
A
S
S
Y
S
T
S
L
S
G
S
Site 39
S338
G
R
K
A
S
S
Y
S
T
S
L
S
G
S
Q
Site 40
T339
R
K
A
S
S
Y
S
T
S
L
S
G
S
Q
K
Site 41
S340
K
A
S
S
Y
S
T
S
L
S
G
S
Q
K
I
Site 42
S342
S
S
Y
S
T
S
L
S
G
S
Q
K
I
H
L
Site 43
S344
Y
S
T
S
L
S
G
S
Q
K
I
H
L
R
K
Site 44
Y354
I
H
L
R
K
K
S
Y
L
C
N
E
C
G
N
Site 45
T362
L
C
N
E
C
G
N
T
F
K
S
S
S
S
L
Site 46
S365
E
C
G
N
T
F
K
S
S
S
S
L
R
Y
H
Site 47
S366
C
G
N
T
F
K
S
S
S
S
L
R
Y
H
Q
Site 48
S367
G
N
T
F
K
S
S
S
S
L
R
Y
H
Q
R
Site 49
S368
N
T
F
K
S
S
S
S
L
R
Y
H
Q
R
I
Site 50
Y371
K
S
S
S
S
L
R
Y
H
Q
R
I
H
T
G
Site 51
T377
R
Y
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 52
S385
G
E
K
P
F
K
C
S
E
C
G
R
A
F
S
Site 53
S392
S
E
C
G
R
A
F
S
Q
S
A
S
L
I
Q
Site 54
S394
C
G
R
A
F
S
Q
S
A
S
L
I
Q
H
E
Site 55
S396
R
A
F
S
Q
S
A
S
L
I
Q
H
E
R
I
Site 56
T405
I
Q
H
E
R
I
H
T
G
E
K
P
Y
R
C
Site 57
Y410
I
H
T
G
E
K
P
Y
R
C
N
E
C
G
K
Site 58
S421
E
C
G
K
G
F
T
S
I
S
R
L
N
R
H
Site 59
S423
G
K
G
F
T
S
I
S
R
L
N
R
H
R
I
Site 60
Y438
I
H
T
G
E
K
L
Y
N
C
N
E
C
G
K
Site 61
S451
G
K
A
L
S
S
H
S
T
L
I
I
H
E
R
Site 62
T452
K
A
L
S
S
H
S
T
L
I
I
H
E
R
I
Site 63
T461
I
I
H
E
R
I
H
T
G
E
K
P
C
K
C
Site 64
S478
C
G
K
A
F
R
Q
S
S
A
L
I
Q
H
Q
Site 65
S479
G
K
A
F
R
Q
S
S
A
L
I
Q
H
Q
R
Site 66
T489
I
Q
H
Q
R
M
H
T
G
E
R
P
Y
K
C
Site 67
Y494
M
H
T
G
E
R
P
Y
K
C
N
E
C
D
K
Site 68
S507
D
K
T
F
R
C
N
S
S
L
S
N
H
Q
R
Site 69
S508
K
T
F
R
C
N
S
S
L
S
N
H
Q
R
I
Site 70
T517
S
N
H
Q
R
I
H
T
G
E
K
P
Y
R
C
Site 71
T545
I
Q
H
Q
R
I
H
T
G
E
K
P
F
K
C
Site 72
T558
K
C
N
T
C
G
K
T
F
R
Q
S
S
S
L
Site 73
S562
C
G
K
T
F
R
Q
S
S
S
L
I
A
H
Q
Site 74
S563
G
K
T
F
R
Q
S
S
S
L
I
A
H
Q
R
Site 75
S564
K
T
F
R
Q
S
S
S
L
I
A
H
Q
R
I
Site 76
T573
I
A
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 77
Y578
I
H
T
G
E
K
P
Y
E
C
N
A
C
G
K
Site 78
S588
N
A
C
G
K
L
F
S
Q
R
S
S
L
T
N
Site 79
S591
G
K
L
F
S
Q
R
S
S
L
T
N
H
Y
K
Site 80
S592
K
L
F
S
Q
R
S
S
L
T
N
H
Y
K
I
Site 81
S605
K
I
H
I
E
E
D
S
L
K
A
D
L
H
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation